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1000+ Urology Basic Science MCQ for DRDO [Solved]

Thursday 9th of March 2023

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1. Which statement is NOT related to Klinefelter syndrome?
A. sterility is the rule
B. has a considerable short life span
C. treatment requires testicular microdissection and sperm extraction
D. 47 XXY karyotype
Answer : B
2. Which of the following does NOT increase in prostate cancer?
A. human kallikrein 2
B. pro-PSA
C. free PSA
D. complexed PSA
Answer : C
3. Which of the following is false regarding Addison`s disease?
A. autoimmune disease in 70% of the cases
B. diagnosed by the rapid ACTH stimulation test
C. characterized by low serum sodium and high potassium
D. may coexist with hyperthyroidism and diabetes mellitus
Answer : D
4. Which period of intrauterine life does the process of organ formation (organogenesis) take place?
A. 9 12 weeks
B. 12 15 weeks
C. 15 18 weeks
D. 18 21 weeks
Answer : A
5. Which of the renal artery occlusive conditions, commonly, do NOT affect renal function?
A. intimal fibroplasia
B. medial fibroplasia
C. medial hyperplasia
D. serosal hyperplasia
Answer : B
6. What does apoptosis mean?
A. programmed cell death
B. new vascular formation
C. uninhibited neural stimulation
D. premature muscular contraction
Answer : A
7. Serum testosterone should be measured:
A. at mid-day
B. at the hour of sleep
C. in the morning
D. late afternoon
Answer : C
8. Which anomaly might accompany horseshoe kidneys?
A. ureteropelvic junction obstruction
B. ureterocele
C. ureteral reflux
D. ureteral atresia
Answer : A
9. What causes ureteral dilation during pregnancy is:
A. mechanical compression by the gravid uterus
B. physiological increase urine flow during pregnancy
C. elevated levels of progesterone
D. reflex inhibition of ureteral contractions
Answer : A
10. During fluoroscopy, what is the main source of radiation hazards that urologists could be exposed to?
A. scattered radiation from the unleaded wall
B. scattered radiation from the patient
C. scattered radiation from the floor and ceiling
D. radiation from the primary beam
Answer : B
11. When should a 70 yrs. man with 40 ml prostate volume, and total PSA of 2.0 ng/ml, go for a prostate biopsy?
A. if PSA reading had exceeded 2.7 ng/ml over 12 months
B. if free PSA reading was less than 0.4 ng/ml
C. if total PSA reading was greater than 8 ng/ml
D. any of the above
Answer : D
12. Which of the prostate medications could result in retrograde ejaculation?
A. tamsulosin
B. doxazosin
C. dutasteride
D. alfuzosin
Answer : A
13. Which artery(ies) supply(ies) the prostate?
A. middle rectal
B. inferior vesical
C. a & b
D. none of the above
Answer : C
14. What is the function of PSA in semen?
A. increases semen volume
B. has antimicrobial activity
C. liquefies the seminal coagulum
D. decreases semen pH
Answer : C
15. Which statement is false concerning the gubernaculua?
A. degenerate after birth
B. called the caudal genital ligaments
C. help guide the testes down through the inguinal canals
D. represent undifferentiated mesenchyme
Answer : A
16. Which lab results indicate poor prognosis of male infertility?
A. azoospermia; normal FSH; increase LH
B. azoospermia; decrease FSH; normal LH
C. oligospermia; increase FSH; normal LH
D. oligospermia; normal FSH; decrease LH
Answer : C
17. What is the most frequent anomaly associated with multicystic renal dysplasia?
A. ureteral atresia
B. vesicoureteral reflux
C. ureteropelvic junction obstruction
D. ureteral duplication
Answer : A
18. What is the most common cause of hematuria in men over 60 yrs.?
A. kidney stones
B. glomerulonephritis
C. BPH
D. bladder cancer
Answer : C
19. What is the earliest clinical sign of puberty in boys?
A. hoarseness of voice
B. enlargement of testes
C. appearance of axillary hair
D. change in body odor
Answer : B
20. What is the most significant innervation of the vas deferens?
A. sympathetic nervous system
B. parasympathetic nervous system
C. somatic nervous system
D. none of the above
Answer : A
21. What could render red urine workup, false positive for hematuria?
A. dehydration
B. myoglobinuria
C. high doses of vitamin C
D. all of the above
Answer : D
22. Which part of the prostate prevents the seminal fluid from entering the bladder during ejaculation?
A. central zone
B. peripheral zone
C. preprostatic tissue
D. anterior fibromuscular stroma
Answer : C
23. Which of the following is NOT a side effect of hydrochlorothiazide?
A. hypercholesterolemia
B. hyperuricemia
C. hypoglycemia
D. hypercalcemia
Answer : C
24. Where is the centre of reflex erection located at?
A. the brain cortex
B. the sacral cord
C. the lumbar cord
D. the hypothalamus
Answer : B
25. To which region does pain, from the left mid ureter, refer to?
A. the loin region
B. the inguinal region
C. the umbilical region
D. the penis or clitoris
Answer : B
26. What does make UTI more common in mid-aged females than in males?
A. short female urethra
B. pregnancy
C. vaginal colonization with enterobacteria
D. all the above
Answer : D
27. Beside renal excretion of sodium, what does atrial natriuretic hormone cause?
A. constriction of renal afferent arterioles
B. renin inhibition
C. aldosterone stimulation
D. rise in systemic blood pressure
Answer : B
28. What is the creatinine clearance in ml/min for a 70 kg man aging 50 yrs. with 1.1 mg/dL serum creatinine?
A. 79.54
B. 44.19
C. 84.15
D. 94.25
Answer : A
29. What are the first and second most common zones from where prostate cancers arise?
A. central then transitional
B. peripheral then transitional
C. peripheral then central
D. transitional then central
Answer : B
30. What is the prime effect of antidiuretic hormone on kidneys?
A. increase collecting duct permeability
B. increase medullary blood flow
C. decrease cortical blood flow
D. decrease potassium secretion
Answer : A
31. What causes Cushing`s disease is:
A. bilateral adrenal hyperplasia
B. pituitary over secretion of ACTH
C. exogenous administration of glucocorticoids
D. immune-mediated disease
Answer : B
32. Between which 2 fascial planes does the prostatic neurovascular bundle travel?
A. prostatic fascia and levator fascia
B. prostate capsule and prostatic fascia
C. Denonvilliers fascia and prostate capsule
D. Denonvilliers fascia and endopelvic fascia
Answer : A
33. Which zone of the prostate originates from the Wolffian duct tissue:
A. central zone
B. peripheral zone
C. transitional zone
D. periurethral glands
Answer : A
34. Which class of the following agents does NOT impair spermatogenesis?
A. alkylating agents
B. phenothiazines
C. antiandrogens
D. prostaglandins
Answer : B
35. Which of the following is false regarding zona glomeruloza?
A. the most superficial layer of the adrenal cortex
B. responses to increased potassium levels, renin or decreased renal blood flow
C. it causes pheochromocytoma
D. secretes aldosterone
Answer : C
36. What are the abnormalities that might accompany complete ureteral duplications?
A. reflux to the upper pole ureter, obstruction to the lower pole ureter
B. reflux to the lower pole ureter, obstruction to the upper pole ureter
C. left ureteropelvic junction obstruction, right ureterocele
D. right ureteropelvic junction obstruction, left ureterocele
Answer : B
37. How long post bilateral orchiectomy, will patients be functionally castrated?
A. immediately
B. after 2 hrs.
C. after 12 hrs.
D. after 24 hrs.
Answer : B
38. What is the nature of the prostate-specific antigen?
A. protease
B. lyase
C. carboxylase
D. hydrolase
Answer : A
39. Which type of renal stone crystals is known as coffin lid?
A. oxalate
B. struvite
C. urate
D. cystine
Answer : B
40. What helps in treating Candida albicans cystitis is:
A. sodium bicarbonate
B. phyto soya
C. ascorbic acid
D. sol palmetto
Answer : A
41. Renal blood flow is autoregulated by:
A. sympathetic nervous system
B. parasympathetic nervous system
C. urinary output
D. afferent arteriolar resistance
Answer : D
42. How many days does spermatogenesis take in the man?
A. 16
B. 32
C. 64
D. 90
Answer : C
43. At which type of renal tubular acidosis (RTA), typically, potassium levels increase?
A. type 1
B. type 2
C. type 3
D. type 4
Answer : D
44. What are the posterior relations of the kidneys?
A. quadratus lumborum and diaphragm
B. psoas and diaphragm
C. psoas and latissimus dorsi
D. transversus abdominus and paraspinous
Answer : A
45. What is the approximated bladder capacity of an 8 yrs. girl?
A. 150 ml
B. 200 ml
C. 250 ml
D. 300 ml
Answer : D
46. At which week of gestation do the primordial germ cells migrate to form the genital ridges?
A. third
B. fourth
C. fifth
D. seventh
Answer : C
47. Branches of what artery travel under the endopelvic fascia form the prostate to the sidewall of the pelvis?
A. obturator artery
B. midrectal artery
C. inferior vesical artery
D. pudendal artery
Answer : D
48. What do urine tests examine to detect hematuria?
A. catalase activity of erythrocytes
B. peroxidase activity of erythrocytes
C. lyase activity of erythrocytes
D. none of the above
Answer : B
49. What is false concerning the collecting system structures of a typical kidney?
A. the renal pelvis could be intra or extra renal
B. the renal pelvis divides into 2 or 3 major calyces
C. major calyces divide into 2 or 3 minor calyces
D. unlike lateral calyces, polar calyces are often paired
Answer : D
50. In which condition can NOT creatinine level be 1200 mg/dL?
A. an aspirate of pelvic urinoma
B. in untreated end-stage renal failure disease
C. a sample from a wound drain after pyeloplasty
D. a sample from suprapubic catheter
Answer : B

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