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Urologic infections and inflammations 1000+ MCQ with answer for DRDO

Thursday 9th of March 2023

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1. What is the preferred antimicrobial prophylaxis for transrectal prostate biopsy?
A. aminoglycoside
B. fluoroquinolone
C. 2nd generation cephalosporin
D. doxycycline
Answer : B
2. What is (are) the cause(s) of recurrent community acquired UTI in women?
A. uncontrolled DM
B. sexual activity with multiple partners
C. high vaginal receptivity to bacterial adherence
D. all of the above
Answer : D
3. What host`s factors do NOT increase the risk of developing infections?
A. advanced age
B. anatomical anomalies
C. poor drug compliance
D. smoking
Answer : C
4. What is the least important measure in indwelling catheter care?
A. cleansing the urethral meatus with aseptic agent
B. careful aseptic insertion of the catheter
C. maintenance of a closed drainage system
D. maintaining a dependant drainage system
Answer : A
5. What is false regarding biopsy-taking from interstitial cystitis bladder?
A. no pathognomonic histology for interstitial cystitis
B. basically, biopsies are performed to exclude carcinomas and other varieties of cystitis
C. diagnostic biopsies include the presence of discrete micro-ulcers and increased numbers of mast cells in the detrusor muscle or submucosa
D. none of the above
Answer : C
6. What is the laboratory differentiation between type III-a and type III-b prostatitis?
A. the cytological examination of the urine and/or EPS
B. transrectal ultrasonographic examination
C. the presence of ?10 WBCs/HPF in the urine with negative culture in type III-b
D. the positive urine culture, and negative EPS support type III-a
Answer : A
7. What is the proper term to describe high bacterial count in urine without pus?
A. asymptomatic bacteriuria
B. sterile pyouria
C. bacterial colonization
D. unresolved bacteriuria
Answer : C
8. What is the ideal antibiotic class for self-start therapy on treating recurrent cystitis in a 32 yrs. married woman?
A. aminopenicillins
B. fluoroquinolones
C. aminoglycosides
D. nitrofurantoins
Answer : B
9. What is true concerning bacterial colonization in the bladder?
A. is always asymptomatic
B. it shows a serological immune antibody response
C. is a common cause of sterile pyuria
D. typically, at this stage, the body demonstrates bacteriuria
Answer : A
10. What is false concerning acute glomerulonephritis?
A. manifested as a sudden onset of hematuria, proteinuria, oliguria, edema, hypertension, and RBC casts in the urine
B. post-streptococcus GN has an incubation period of 1-3 weeks with specific strains of group A beta-hemolytic streptococcus
C. the triad of sinusitis, pulmonary infiltrates, and nephritis, suggests Wegener granulomatosis
D. C3, C4, ESR and antistreptolysin O titer are increased
Answer : D
11. During the initial 3-month period of HIV infection, what would be the best diagnostic lab test?
A. viral load assay
B. western blot analysis
C. southern blot analysis
D. HIV-1/HIV-2 serology assay
Answer : A
12. What are the diagnostic findings on cystometrogram for BPS/IC?
A. discomfort on placing urethral catheter and pain on bladder filling
B. difficulty in zeroing the pressure and diminished response to first cough
C. low filling pressure but high voiding pressure
D. uninhibited bladder contractions with a relative bladder hypotonia
Answer : A
13. What is true regarding contrast CT imaging for a renal abscess?
A. abscess appears as a low attenuation cystic cavity containing gas
B. renal parenchyma around the abscess cavity may show hypo enhancement in nephrogram phase
C. associated fascial and septal thickening are seen with obliteration of perinephric fat
D. all of the above
Answer : D
14. What is false concerning Chlamydia trachomatis urethritis in males:
A. produces yellow whitish, scanty, frothy urethral discharge
B. shows gram (+), extracellular diplococcic
C. infection could be contracted from the spouses eyes
D. responds fairly to azithromycin
Answer : B
15. Irritative LUTS and dyspareunia in postmenopausal women are most likely to be due to:
A. giggle incontinence
B. estrogen deficiency
C. cystitis glandularis
D. cystitis cystica
Answer : B
16. Asymptomatic bacteriuria should be treated in the following situations:
A. in the elderly
B. in long-term catheterized patient
C. in pregnancy
D. none of the above
Answer : C
17. In males, HIV infection increases the incidence of the following genitourinary tumors:
A. testicular
B. renal
C. penile
D. all of the above
Answer : D
18. Patients with bladder pain syndrome have:
A. a history of repeated urologic and/or gynecologic procedures
B. 10 fold higher incidence of childhood voiding problems
C. 4 fold higher incidence of anxiety-depression syndrome
D. 6 fold higher incidence of psychosomatic disorders
Answer : B
19. What is true concerning granulomatous inflammation of the prostate?
A. is a common cause of elevated PSA level
B. might follow BCG treatment
C. is sequelae of untreated type III-b prostatitis
D. shows homogenous enhancement following Gd-DTPA on prostate MRI
Answer : B
20. What is false regarding Gonorrheal STD in women?
A. nucleic acid amplification tests are the preferred to diagnose Gonococcal and Chlamydial infections
B. shows dark yellow, purulent, thick urethral discharge
C. the most common site of the infection is the endocervix
D. the incubation period is 2 3 weeks
Answer : D
21. Which treatment modality has NO proven efficacy in CP/CPPS?
A. selective nerve block
B. balloon dilation
C. botulinum A toxin injection
D. ESWL
Answer : B
22. What is false regarding viral cystitis?
A. in pediatrics, adenovirus types 11 and 21 could result in hemorrhagic cystitis
B. immunosuppressed children are especially susceptible to Cytomegalovirus and Adenoviruses 7, 21, and 35
C. in pediatrics, acute viral cystitis might present as acute retention of urine
D. classically, treatment should be culture-specific
Answer : D
23. What is false regarding Fournier`s gangrene?
A. is defined as a polymicrobial chronic infection of the perineal, perianal, or genital areas
B. as the disease progresses, branches from the inferior epigastric, deep circumflex iliac, and external pudendal arteries get thrombosed
C. presents as a dark skinned-scrotum, subcutaneous crepitation, and foul smell
D. surgical debridement often spares the testes
Answer : A
24. A 44 yrs. male presents with recurrent left pyelonephritis and Proteus infection. His kidney is dilated and contains a stone. A renal biopsy showed foamy macrophages with neutrophils and cellular debris. What is the treatment?
A. PCNL after treating the infection
B. cystoscopy and placing a retrograde ureteral stent followed by ESWL
C. perc. nephrostomy and placing antegrade ureteral stent
D. nephrectomy
Answer : D
25. What is essential on diagnosing bladder pain syndrome BPS/IC?
A. sterile pyuria on 3 consecutive cultures
B. the presence of glomerulations and/or Hunner`s ulcer on endoscopy
C. pain and discomfort related to the bladder
D. urgency and frequency with no documented infection
Answer : C
26. What is false concerning the cystoscopic findings of interstitial cystitis?
A. Hunner`s ulcers are multiple ulcerative patches surrounded by mucosal congestion on the dome or lateral walls
B. ulcers might get distorted after overdistention, because discrete areas of mucosal scarring rupture during the procedure
C. in non-ulcerative type, overdistention demonstrates glomerulations on the dome and lateral walls
D. overdistention results in mucosal tears and submucosal hemorrhage
Answer : B
27. What is true concerning the treatment of catheter associated bacteriuria?
A. should be flushed frequently, but no antibiotic is advised
B. should be treated if febrile UTI has developed
C. should be treated only if urine culture is positive
D. should be treated once the catheter is removed
Answer : B
28. What is the mortality rate of emphysematous pyelonephritis?
A. 43%
B. 53%
C. 63%
D. 73%
Answer : A
29. What is false concerning sepsis syndrome?
A. poor tissue perfusion manifests as hyperlactemia and decreased capillary refill
B. acute oliguria indicates an organ dysfunction and circulatory collapse
C. septic shock is an extreme form of sepsis when hypotension persists despite adequate fluid resuscitation
D. hypotension is a sign of hyperdynamic circulation at an early septic shock
Answer : D
30. Which of the following factors increases the risk of UTI due to facilitation of microbial ascent?
A. sexual activity
B. the use of spermicide
C. estrogen depletion
D. fecal incontinence
Answer : D
31. What condition(s) could occur in schistosomal ureter?
A. beading of the lower ureteral segment
B. ureteral fibrosis and calcifications of the distal ureter
C. stricture at the uretero-vesical junction
D. all of the above
Answer : D
32. What is true concerning ovarian vein syndrome?
A. manifests as recurrent renal colics due to ureteral obstruction
B. treatment is surgical mobilization of ureter and ligation of the vein
C. commonly, occurs at the left side
D. the pain worsens on sitting upright and during pregnancy
Answer : B
33. What is the best statement that describes the action of antiproliferative factor?
A. inhibits bladder epithelial cell proliferation
B. inhibits the bladder proliferative growth factors
C. stimulates the proliferation inhibitory factors
D. none of the above
Answer : A
34. Management of acute epididymo-orchitis in hospitalized patients includes all of the following, EXCEPT:
A. scrotal support and elevation
B. ice packs
C. non-steroidal anti-inflammatory agents
D. urethral catheterization
Answer : D
35. What is false concerning cystitis glandularis?
A. rarely, the urothelial cell nests show a central lumen lined by glandular epithelium
B. In some cases, it may form polypoid masses that mimic urothelial neoplasms
C. It might appear as multinodular exophytic mass seen on cystoscopy
D. cystitis cystica and cystitis glandularis frequently coexist in the same specimen Answer : A
36. What are the commonest organisms causing acute epididymitis in males younger than 35 yrs.?
A. N. gonorrhea and C. trachomatis
B. E. coli and Pseudomonas species
C. Mycoplasma genitalium and Ureaplasma species
D. Trichomonas vaginalis and Gardnerella vaginalis
Answer : A
37. What is false concerning antiretroviral medications?
A. multiple antiretroviral drugs can be combined into a single pill
B. might cause radiolucent renal stones
C. can lead to a significant rise in the serum level of PDE5 inhibitors, if taken simultaneously
D. have the advantage of structured treatment interruptions (drug holidays)
Answer : D
38. What type of bladder cells secretes antiproliferative factor?
A. bladder epithelial cells
B. type C nerve endings in the bladder
C. type A delta nerve endings in the bladder
D. the innermost longitudinal fibres of detrusor muscle
Answer : A
39. Which of the following does NOT cause unresolved bacteriuria?
A. giant staghorn stone
B. perivesical abscess with fistula to the bladder
C. bacterial resistance
D. self-inflicted infection
Answer : B
40. How should a proper routine urine specimen be collected?
A. early morning sample, after cleansing the perineum and meatus
B. by urethral catheterization under strict aseptic technique
C. a clean catch of midstream voided urine
D. by suprapubic aspiration, as urine is sterile
Answer : C
41. What are the most commonly affected organs by genitourinary schistosomiasis?
A. kidneys and adrenals
B. bladder and ureters
C. prostate and vasa
D. testes and epididymi
Answer : B
42. What is true regarding acute pyelonephritis?
A. a cause of obstruction should be sought
B. PCN is placed to decompress the kidney and preserve renal function
C. blood-born staphylococci are commoner than ascending E.coli infections
D. blood and urine cultures must dictate the antibiotic choice from day 1
Answer : A
43. What is true regarding genitourinary TB?
A. commonly, TB enters the urinary tract via intravesical instillation of attenuated live BCG to treat bladder cancer
B. CT urography may show infundibular stricture with or without hydrocalicosis
C. renal ultrasonography reveals calyceal erosions moth-eaten calyx
D. TB of the vas appears, clinically, as a thin hard strictured tube
Answer : B
44. Using low-dose prophylactic or suppressive antimicrobials might be an option in treating the following type of prostatitis:
A. acute bacterial prostatitis presenting with abscess formation
B. recurrent or refractory chronic bacterial prostatitis
C. asymptomatic prostatitis with pyuria resistant to common antimicrobials
D. curiously, chronic inflammatory prostatitis could respond to low-dose suppressive antibiotic
Answer : B
45. What could cause scrotal sinus?
A. improperly drained hair follicle scrotal abscess
B. syphilitic orchitis
C. tuberculous epididymitis
D. all of the above
Answer : D
46. What antimicrobial agent treats UTI and does NOT alter the gut flora?
A. trimethoprim- sulfamethoxazole
B. fluoroquinolones
C. aminoglycosides
D. nitrofurantoins
Answer : D
47. What is (are) the prominent clinical finding(s) in the diagnosis of acute pyelonephritis?
A. fever, chills, abdominal pain
B. costovertibral angle tenderness
C. hypogastric and loin pain
D. flank pain, dysuria
Answer : B
48. Which of the following has NO role in bacterial colonization in the prostate?
A. intra-prostatic ductal reflux
B. paraphimosis
C. specific blood groups
D. unprotected anal intercourse
Answer : B
49. What condition does NOT present as an acute loin pain with fever and marked flank tenderness?
A. ascending UTI causing acute lobar nephronia
B. acute pyelonephritis in a transplanted kidney
C. infected renal subcapsular hematoma
D. perinephric abscess causing septicemia
Answer : B
50. What is false concerning peri-renal abscess?
A. could result from intra-renal abscess of ascending infection
B. urine culture might be negative
C. plain KUB X-ray has no value in the diagnosis
D. surgical drainage is the proper treatment
Answer : C

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