the lesion is solitary and no associated CIS
physically, a surgical margin of 2-cm can be obtained
the resected area should be far enough from ureteral orifices and the bladder neck
all of the following
D. all of the following
often of high-grade sarcomas
often associated with muscularis propria invasion
due to vesical polyps occluding ureteric orifices
should be resected but not diathermized
sensitivity to chemotherapy and age at presentation
anatomic location and extent of the tumor
histologic type of the tumor and sensitivity to radiotherapy
tumors stage and grade
obstructive uropathy
painless hematuria
pain radiating to the groin
locally advanced tumor
2 - 4%
4 - 6%
6 - 8%
8 - 10%
radical cysto-prostatectomy
anterior pelvic exenteration
bilateral pelvic lymphadenectomy
creation of a urinary diversion
irritative bladder symptoms
obstructive bladder symptoms
palpable suprapubic mass on physical examination
painless profuse hematuria
nodular or sessile lesions usually invade muscle
papillary bladder tumors are typical of low stage and grade
carcinoma in situ appears as a flat, velvety patch
sarcomas commonly invade bladder base and ureteral orifices causing obstructions
tumor stage
tumor grade
lymphovascular invasion
lymph node spread
30%
40%
50%
60%
patients with carcinoma in situ
patients with completely resected solitary tumor
patients with preserved kidney and liver functions after 2 courses of BCG
patients with leiomyosarcoma
history of pulmonary TB
total incontinence
immunosuppression
impaired renal function
the anterior urethra drains into the inguinal and pelvic nodes
the posterior urethra drains into the pelvic nodes
the proximal two-thirds drain into the external and internal iliac nodes
the distal one-third drains into the obturator nodes
adenocarcinoma
transitional cell carcinoma
squamous cell carcinoma
comparable
upper ureter
middle ureter
lower ureter
comparable
epirubicin
mitomycin c
BCG
none of the above
well-differentiated tumor with broad-based invasive font
marked atypia distributed on wide areas of superficial urothelium
atypia is present
no atypia but marked degenerative epithelial changes
multifocality
high tumor grade and advanced stage
presence of CIS
all of the above
bladder perforation
obturator nerve reflex
vesico-ureteral reflux
terrible bleeding
adenocarcinoma
transitional cell carcinoma
squamous cell carcinoma
basal cell carcinoma
10%
20%
30%
40%
urine cytology
CT urography
cystoscopy
renal function tests
frequently found in association with high-grade or extensive TCC
has a rate of progression to muscle invasion of 10-25%
significant areas of CIS are easily missed by routine cystoscopy
treatment begins with TURBT
leiomyosarcoma
rhabdosarcoma
carcinosarcoma
neurosarcoma
immediately before operation
immediately before incision and post-operative for 1 day
immediately before incision and post-operative for 15 days
immediately before incision and post-operative for 30 days
the standard treatment is transurethral resection
the prognosis for inverted papilloma is pathetic, with a recurrence rate of approximately 65%
the likelihood of synchronous urothelial carcinoma is 26%
has been shown to harbor p53 gene mutations
cisplatin
BCG
mitomycin C
5-fluorouracil
high specificity
high sensitivity
high reliability
strong validity
adenocarcinoma
transitional cell carcinoma
squamous cell carcinoma
basal cell carcinoma
2%
5%
70%
90%
adenocarcinoma
transitional cell carcinoma
squamous cell carcinoma
basal cell carcinoma