right hydrocele
left varicocele
painless hematuria
hypertension
A. right hydrocele
fibrosarcoma
leiomyosarcoma
carcinoid
adult Wilm`s tumor
. Metastatic tumors to the kidney are common from all of the following organs, EXCEPT:
lungs
thyroid
breasts
. What is the relapse rate for completely resected RCC after radical nephrectomy?
1- 10%
10 - 20%
20 - 30%
acquired cystic renal disease
juvenile nephronophthisis
medullary sponge kidney
bilateral multicystic dysplastic kidney
abdominal CT
chest X-ray
renal function test
liver function test
never
unlikely
likely
always
type II DM, especially in males
hypertension
obesity, especially in females
cigarette smoking
. What is an indication for radical nephrectomy?
a 6-cm, polar tumor
bilateral RCC
locally advanced RCC
. What is false concerning imaging studies for preoperative evaluation of RCC case?
in case of bone pain or elevated serum calcium and/or alkaline phosphatase levels, an isotopic bone scan is required
renal arteriography accurately localizes central scaring and tumor necrosis
trans-esophageal echocardiography helps assess vena caval and right atrial tumor thrombi
nuclear size, outline, and nucleoli
cohesiveness and the degree of cellular atypia
chromatin structure and content of the interphase nucleus
multinucleation and mitosis
papillary subtype of RCC has a tendency to multifocality
chromosome 13 alterations are common in the development of clear cell renal carcinoma
a solid mass on CT that enhances more than 15 HU is suggestive of RCC
bilateral involvement in RCC either synchronously or metachronously occurs in 2% to 4% of patients
clear cell
chromophobe
papillary
renal medullary
hepatic cysts are the most common extra-renal manifestation
might experience cyst hemorrhage, renal infection, or nephrolithiasis
typically, complain of flank pain or intermittent hematuria in the early twenties
hypertension and CRF commonly occur in the fifth decade of life
. The second most common RCC subtype is:
collecting duct b. clear cell
papillary
chromophobe
radiographically, it is indistinguishable from RCC
has a female predominance
has a benign clinical course
has a peak incidence in the third decade of life
repeat ablation
active surveillance
salvage surgery
radical nephrectomy
most classic AMLs eventually undergo malignant transformation to sarcomatoid and epithelioid AML
the preferred treatment is nephroureterectomy followed by active surveillance
angiographic embolization and/or nephron-sparing surgery is advised for symptomatic AMLs greater than 4 cm
extra-renal sites include the pancreas, salivary glands, and thyroids
. In RCC, ipsilateral adrenal metastasis occurs in:
0.3 - 2%
2 - 10%
11 - 18%
80%
85%
90%
95%
. What is false concerning targeted molecular therapy?
is a personalized medical therapy devised to meet each persons individual needs for cancer`s specifications
treats cancer by interrupting unique molecular abnormalities that drive cancer growth
some cancer types have different molecular targets
. Manifestations of paraneoplastic syndrome associated with RCC include all of the following, EXCEPT:
anemia and erythrocytosis
hepatic dysfunction and elevated human chorionic gonadotropin levels
hypocalcemia
ARPKD accounts for 5% of ESRD in children
more than one-half of patients with ARPKD require kidney transplant before age 20 years
ADPKD is a common cause of ESRD
uncommonly, juvenile nephronophthisis causes ESRD in children
male gender
hypertension
renal insufficiency
all of the above
they follow a benign clinical course
they have a bimodal age distribution
they are more common in men than in women
none of the above
20%
30%
40%
50%
RCC
AML
teratoma
any of the above
papillary RCC
renal metastases
renal oncocytoma
renal xanthogranuloma
is the first and most reliable radiologic examination to study IVC thrombi
is reserved for patients with equivocal MRI or CT findings
is obsolete and has fallen out of use
carries a risk of IVC terrible bleeding that outweighs the diagnostic merits
most lesions ≤ 4 cm are asymptomatic
renal masses with fat content is pathognomonic for AML
renal biopsy from AML carries a high risk of hemorrhage
may coexist with malignant lesions, such as sarcomas and RCCs
autosomal recessive polycystic kidney disease
autosomal dominant polycystic kidney disease
multicystic dysplastic kidney disease
juvenile nephronophthisis