the central scar on CT or MRI, and the spoke-wheel pattern of vessels on angiograms are not specific to oncocytoma
calcification, necrosis, and hemorrhage are rare in oncocytomas
it is thought to arise from the basement membrane of proximal convoluted tubules
treatment is partial nephrectomy or tumor excision
C. it is thought to arise from the basement membrane of proximal convoluted tubules
margin status and grade
tumor size
tumor stage
the time interval between the tumor emergence and excision
clear cell
chromophobe
papillary
renal medullary
cyst aspiration and sclerosis
partial nephrectomy
endoscopic marsupialization and fulguration of the cyst
administration of TKIs
nuclear size, outline, and nucleoli
cohesiveness and the degree of cellular atypia
chromatin structure and content of the interphase nucleus
multinucleation and mitosis
I
II
III
IV
. The second most common RCC subtype is:
collecting duct b. clear cell
papillary
chromophobe
is the first and most reliable radiologic examination to study IVC thrombi
is reserved for patients with equivocal MRI or CT findings
is obsolete and has fallen out of use
carries a risk of IVC terrible bleeding that outweighs the diagnostic merits
papillary subtype of RCC has a tendency to multifocality
chromosome 13 alterations are common in the development of clear cell renal carcinoma
a solid mass on CT that enhances more than 15 HU is suggestive of RCC
bilateral involvement in RCC either synchronously or metachronously occurs in 2% to 4% of patients
autosomal dominant polycystic kidney disease (ADPKD)
developmental cystic renal disease
inherited cystic renal disease
systemic disease with associated renal cysts
most lesions ≤ 4 cm are asymptomatic
renal masses with fat content is pathognomonic for AML
renal biopsy from AML carries a high risk of hemorrhage
may coexist with malignant lesions, such as sarcomas and RCCs
. In RCC, ipsilateral adrenal metastasis occurs in:
0.3 - 2%
2 - 10%
11 - 18%
they follow a benign clinical course
they have a bimodal age distribution
they are more common in men than in women
none of the above
type II DM, especially in males
hypertension
obesity, especially in females
cigarette smoking
1
2
3
4
70 - 85%
55 - 70%
40 - 55%
25 - 40%
male gender
hypertension
renal insufficiency
all of the above
mutations in the MCKD1 (chromosome 1q21) gene
mutations in the MCKD2 (chromosome 16q12) gene
inherited in an autosomal dominant fashion
all of the above
right hydrocele
left varicocele
painless hematuria
hypertension
adenoma with clear cell
papillary adenoma
metanephric adenoma
none of the above
acquired cystic renal disease
juvenile nephronophthisis
medullary sponge kidney
bilateral multicystic dysplastic kidney
< - 10 HU
< - 20 HU
< 10 HU
< 20 HU
papillary RCC
renal metastases
renal oncocytoma
renal xanthogranuloma
fibrosarcoma
leiomyosarcoma
carcinoid
adult Wilm`s tumor
abdominal CT
chest X-ray
renal function test
liver function test
glomerulocystic kidney disease
developmental cystic renal disease
Juvenile nephronophthisis
medullary cystic kidney disease
RCC
AML
teratoma
any of the above
. What is an indication for radical nephrectomy?
a 6-cm, polar tumor
bilateral RCC
locally advanced RCC
20%
30%
40%
50%
80%
85%
90%
95%
most classic AMLs eventually undergo malignant transformation to sarcomatoid and epithelioid AML
the preferred treatment is nephroureterectomy followed by active surveillance
angiographic embolization and/or nephron-sparing surgery is advised for symptomatic AMLs greater than 4 cm
extra-renal sites include the pancreas, salivary glands, and thyroids