What type of renal adenomas is a precursor to papillary RCC?
adenoma with clear cell
papillary adenoma
metanephric adenoma
none of the above
Correct Answer :
B. papillary adenoma
papillary adenoma is a premalignant neoplasm that progresses to papillary RCC.
Related Questions
d. 19 - 26%
. What is false regarding radical nephrectomy operation?
nodal involvement doesn`t influence prognosis
renal artery should be ligated before the vein to avoid kidney ballooning
cardiopulmonary bypass with deep hypothermic circulatory arrest is performed in patients with supra-diaphragmatic tumor thrombi
d. hypertension
. Metastatic tumors to the kidney are common from all of the following organs, EXCEPT:
lungs
thyroid
breasts
Antenatal sonography is the diagnostic tool for the following condition:
glomerulocystic kidney disease
developmental cystic renal disease
Juvenile nephronophthisis
medullary cystic kidney disease
What is false concerning end-stage renal disease (ESRD)?
ARPKD accounts for 5% of ESRD in children
more than one-half of patients with ARPKD require kidney transplant before age 20 years
ADPKD is a common cause of ESRD
uncommonly, juvenile nephronophthisis causes ESRD in children
What type of Bosniak renal cysts accompanies tumor masses in 5% of cases?
I
II
III
IV
Which of the following renal tumors carries the best prognosis?
fibrosarcoma
leiomyosarcoma
carcinoid
adult Wilm`s tumor
After radical nephrectomy, what is the 5-year survival rate for stage I RCC?
80%
85%
90%
95%
Which of the following factors is associated with increased survival in patients with metastatic kidney tumors?
physically active patients with good performance status
extirpation of the primary tumor
long disease-free interval between initial nephrectomy and the emergence of secondaries
all of the above
d. unilateral RCC with a functioning opposite kidney, but at risk for future impairment
. What is the relapse rate for completely resected RCC after radical nephrectomy?
1- 10%
10 - 20%
20 - 30%
What type of renal adenomas is a precursor to papillary RCC?
adenoma with clear cell
papillary adenoma
metanephric adenoma
none of the above
What is false concerning ADPKD patients?
hepatic cysts are the most common extra-renal manifestation
might experience cyst hemorrhage, renal infection, or nephrolithiasis
typically, complain of flank pain or intermittent hematuria in the early twenties
hypertension and CRF commonly occur in the fifth decade of life
What is false concerning metanephric adenoma?
radiographically, it is indistinguishable from RCC
has a female predominance
has a benign clinical course
has a peak incidence in the third decade of life
Fuhrmans grading system for renal cell carcinoma relies on:
nuclear size, outline, and nucleoli
cohesiveness and the degree of cellular atypia
chromatin structure and content of the interphase nucleus
multinucleation and mitosis
On ultrasonography, what are the percentages of incidentally discovered renal masses that will later be malignant on further workup?
70 - 85%
55 - 70%
40 - 55%
25 - 40%
On histological examination of a resected renal tumor, the presence of multiple mitochondria observed on electron microscopy is diagnostic for:
renal oncocytoma
multiloculated cystic nephromas
metanephric adenoma
adenoma with clear cell
What is the likelihood that Bosniak type III renal cysts accompany malignant masses?
never
unlikely
likely
always
d. 30 - 40%
. What is false concerning imaging studies for preoperative evaluation of RCC case?
in case of bone pain or elevated serum calcium and/or alkaline phosphatase levels, an isotopic bone scan is required
renal arteriography accurately localizes central scaring and tumor necrosis
trans-esophageal echocardiography helps assess vena caval and right atrial tumor thrombi
What is false concerning renal angiomyolipoma (AML)?
most lesions ≤ 4 cm are asymptomatic
renal masses with fat content is pathognomonic for AML
renal biopsy from AML carries a high risk of hemorrhage
may coexist with malignant lesions, such as sarcomas and RCCs
Inherited renal cystic disease(s) include(s) the following:
glomerulocystic kidney disease (GCKD)
Juvenile nephronophthisis (JNPHP)
medullary cystic kidney disease
all of the above
Which of the following is NOT a risk factor for RCC?
type II DM, especially in males
hypertension
obesity, especially in females
cigarette smoking
d. prior to kidney transplant
. What is an indication for radical nephrectomy?
a 6-cm, polar tumor
bilateral RCC
locally advanced RCC
Routine metastatic evaluation in RCC cases should include all of the following, EXCEPT:
abdominal CT
chest X-ray
renal function test
liver function test
d. all of the above
. What is the most common histologic subtype of renal sarcomas?
rhabdomyosarcoma
nephrosarcoma
leiomyosarcoma
In renal mass(es), the main indication to take a renal biopsy is the suspicion of:
papillary RCC
renal metastases
renal oncocytoma
renal xanthogranuloma
Regarding simple renal cysts, fluid attenuation on non-contrast CT series is:
< - 10 HU
< - 20 HU
< 10 HU
< 20 HU
What is the treatment of a 3-cm renal mass suggestive of RCC adjacent to a huge renal cyst?
cyst aspiration and sclerosis
partial nephrectomy
endoscopic marsupialization and fulguration of the cyst
administration of TKIs
What is false concerning renal oncocytoma?
the central scar on CT or MRI, and the spoke-wheel pattern of vessels on angiograms are not specific to oncocytoma
calcification, necrosis, and hemorrhage are rare in oncocytomas
it is thought to arise from the basement membrane of proximal convoluted tubules
treatment is partial nephrectomy or tumor excision
What is false regarding multiloculated cystic nephromas?
they follow a benign clinical course
they have a bimodal age distribution
they are more common in men than in women
none of the above
d. renal vein thrombi can be resected after incising the vein between 2 vascular clamps
. Manifestations of paraneoplastic syndrome associated with RCC include all of the following, EXCEPT:
anemia and erythrocytosis
hepatic dysfunction and elevated human chorionic gonadotropin levels
hypocalcemia
According to Fuhrmans classification system for nuclear grading in RCC, nuclear size of 20 μg with irregular outline and prominent nucleoli is grade:
1
2
3
4