fibrosarcoma
leiomyosarcoma
carcinoid
adult Wilm`s tumor
C. carcinoid
most lesions ≤ 4 cm are asymptomatic
renal masses with fat content is pathognomonic for AML
renal biopsy from AML carries a high risk of hemorrhage
may coexist with malignant lesions, such as sarcomas and RCCs
hepatic cysts are the most common extra-renal manifestation
might experience cyst hemorrhage, renal infection, or nephrolithiasis
typically, complain of flank pain or intermittent hematuria in the early twenties
hypertension and CRF commonly occur in the fifth decade of life
. The second most common RCC subtype is:
collecting duct b. clear cell
papillary
chromophobe
hyperattenuating renal cyst
solitary renal cyst
uncomplicated renal cyst
focal renal cyst
1
2
3
4
I
II
III
IV
most classic AMLs eventually undergo malignant transformation to sarcomatoid and epithelioid AML
the preferred treatment is nephroureterectomy followed by active surveillance
angiographic embolization and/or nephron-sparing surgery is advised for symptomatic AMLs greater than 4 cm
extra-renal sites include the pancreas, salivary glands, and thyroids
margin status and grade
tumor size
tumor stage
the time interval between the tumor emergence and excision
. Manifestations of paraneoplastic syndrome associated with RCC include all of the following, EXCEPT:
anemia and erythrocytosis
hepatic dysfunction and elevated human chorionic gonadotropin levels
hypocalcemia
80%
85%
90%
95%
ARPKD accounts for 5% of ESRD in children
more than one-half of patients with ARPKD require kidney transplant before age 20 years
ADPKD is a common cause of ESRD
uncommonly, juvenile nephronophthisis causes ESRD in children
papillary RCC
renal metastases
renal oncocytoma
renal xanthogranuloma
. What is false concerning targeted molecular therapy?
is a personalized medical therapy devised to meet each persons individual needs for cancer`s specifications
treats cancer by interrupting unique molecular abnormalities that drive cancer growth
some cancer types have different molecular targets
progress to ESRD in the sixth decade of life
hypertension is seen in 80% of patients with ADPKD aged 20-34 years
aortic valve stenosis in 25%
manifestations are more significant in patients with the PKD2 genotype
they follow a benign clinical course
they have a bimodal age distribution
they are more common in men than in women
none of the above
is the first and most reliable radiologic examination to study IVC thrombi
is reserved for patients with equivocal MRI or CT findings
is obsolete and has fallen out of use
carries a risk of IVC terrible bleeding that outweighs the diagnostic merits
is > 90% in Bosniak type IV renal cysts
in patients receiving renal transplants for polycystic kidney disease is 48% higher than that expected in the general population
all of the above
simple renal cysts might turn malignant in < 4% of cases
cyst aspiration and sclerosis
partial nephrectomy
endoscopic marsupialization and fulguration of the cyst
administration of TKIs
male gender
hypertension
renal insufficiency
all of the above
papillary subtype of RCC has a tendency to multifocality
chromosome 13 alterations are common in the development of clear cell renal carcinoma
a solid mass on CT that enhances more than 15 HU is suggestive of RCC
bilateral involvement in RCC either synchronously or metachronously occurs in 2% to 4% of patients
. What is false regarding radical nephrectomy operation?
nodal involvement doesn`t influence prognosis
renal artery should be ligated before the vein to avoid kidney ballooning
cardiopulmonary bypass with deep hypothermic circulatory arrest is performed in patients with supra-diaphragmatic tumor thrombi
the quality of the kidney and renal function prior to surgery
the quantity of vascularized parenchymal mass preserved after excision
the tumor
warm ischemia time
. What is the most common histologic subtype of renal sarcomas?
rhabdomyosarcoma
nephrosarcoma
leiomyosarcoma
acquired cystic renal disease
juvenile nephronophthisis
medullary sponge kidney
bilateral multicystic dysplastic kidney
. In RCC, ipsilateral adrenal metastasis occurs in:
0.3 - 2%
2 - 10%
11 - 18%
. What is the relapse rate for completely resected RCC after radical nephrectomy?
1- 10%
10 - 20%
20 - 30%
autosomal dominant polycystic kidney disease (ADPKD)
developmental cystic renal disease
inherited cystic renal disease
systemic disease with associated renal cysts
fibrosarcoma
leiomyosarcoma
carcinoid
adult Wilm`s tumor
renal oncocytoma
multiloculated cystic nephromas
metanephric adenoma
adenoma with clear cell
abdominal CT
chest X-ray
renal function test
liver function test