Tumors of the prostate MCQ Question with Answer

Tumors of the prostate MCQ with detailed explanation for interview, entrance and competitive exams. Explanation are given for understanding.

Question No : 8
Concerning prostate cancers, a pre-treatment PSA velocity of > 2 ng/mL/yr is associated with an increased risk of:

pathological bone fractures

biochemical failure following radiation therapy

hepato-renal disease following chemotherapy

upgrading the pre-treatment risk stratification

Question No : 9
What is true surrounding PSA?

black individuals produce more PSA than whites

ejaculation can lead to a false decrease in PSA

pro-PSA is the serum proactive form of PSA molecule

prostate cancer cells make more PSA than normal prostate tissues do

Question No : 10
In which of the following cases PSA testing is NOT indicated:

72 yrs. man newly diagnosed BPH with normal DRE

2 weeks post TURP for obstructing cancerous prostate

screening for prostate cancer in 75 yrs. old Caucasian man

43 yrs. man with obstructive LUTS, who had a first-degree relative diagnosed with prostate cancer before age 65

Question No : 11
What is true regarding seminal vesicles` involvement in prostate cancer?

is almost always due to direct extension (T2c)

it is involved in 85% of positive surgical margins following radical prostatectomy

it carries a poor prognosis

none of the above

Question No : 12
In which of the following PSA readings prostate cancer is least suspected?

PSA velocity of 0.35 ng/mL/y, when the PSA is ≤ 2.5 ng/mL

PSA velocity of 0.75 ng/mL/y, when the PSA is 4 10 ng/mL

t-PSA is 2.8 ng/mL, f-PSA 0.94 ng/mL

t-PSA is 3.7 ng/mL, f-PSA 0.51 ng/mL

Question No : 13
In which of the following situations prostate biopsy is most indicated?

normal DRE, abnormal PSA

abnormal DRE, abnormal PSA

abnormal DRE, normal PSA

hyperechoic areas on TRUS

Question No : 14
Which of the following tests has the highest positive predictive value for prostate cancer?

PSA

digital rectal examination

transrectal ultrasonography

human kallikrein 2