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Urothelial tumors of the upper & lower urinary tracts MCQ Question with Answer

Urothelial tumors of the upper & lower urinary tracts MCQ with detailed explanation for interview, entrance and competitive exams. Explanation are given for understanding.

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Question No : 22
During women`s life span, what percentage of women will develop keratinizing squamous metaplasia of the bladder?

10%
20%
30%
40%

Question No : 23
The treatment of muscle-invasive bladder cancer in men includes all of the following, EXCEPT:

radical cysto-prostatectomy
anterior pelvic exenteration
bilateral pelvic lymphadenectomy
creation of a urinary diversion

Question No : 24
The most significant prognostic factors for survival in female urethral cancers are:

sensitivity to chemotherapy and age at presentation
anatomic location and extent of the tumor
histologic type of the tumor and sensitivity to radiotherapy
tumors stage and grade

Question No : 25
What gene mutation is common in carcinoma-in-situ of urinary bladder?

RB
cyclin A
HRAS
CD-44

Question No : 26
What percentage of bladder cancers is squamous cell type in origin?

2%
5%
70%
90%

Question No : 27
Risk factors for recurrence and progression of bladder cancers include the following:

multifocality
high tumor grade and advanced stage
presence of CIS
all of the above

Question No : 28
What is the most effective adjuvant intravesical therapy for bladder tumors?

cisplatin
BCG
mitomycin C
5-fluorouracil