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Definition of antagonist

the main character, person, group, society, nature, force, spirit world, bad guy, or villain of a film or script who is in adversarial conflict with the film's hero, lead character orprotagonist; also sometimes termed the heavy.

Film Terms

Other definitions of antagonist

A substance that acts against and blocks an action. Antagonist is the opposite of ago- nist. Antagonists and agonists are key players in the chemistry of the human body and in pharmacology.

Medical Science