1000+ Urology Basic Science MCQ for IBPS PO [Solved]

1. Which agent is most likely to cause hemorrhagic cystitis?
A. cisplatin
B. ifosfamide
C. phosphomycin
D. amphotericin B
Answer : B

2. Which type of urinary casts are solidified TammHorsfall mucoproteins secreted from the tubular epithelial cells of individual nephrons?
A. granular
B. hyaline
C. waxy
D. pigment
Answer : B

3. Which statement regarding post-obstructive diuresis (POD) is false?
A. urine production exceeding 200 ml/hr for 2 consecutive hours or producing greater than 3 L of urine in 24 hours is diagnostic of POD
B. pathologic POD can be exacerbated by excessive fluid replacement
C. the replacement fluid choice is ringer lactate
D. fluid resuscitation depends on the degree of dehydration
Answer : C

4. In utero, which hormone stimulates the development of the prostate gland?
A. estradiol
B. DHT
C. FSH
D. testosterone
Answer : B

5. Which innervations mediate detumescence?
A. cavernous nerves
B. dorsal nerves of the penis
C. sympathetic nervous system
D. parasympathetic nervous system
Answer : C

6. Which action of thigh muscles could be impaired if the obturator nerve was injured during endoscopic resection of bladder tumors?
A. adduction
B. abduction
C. flexion
D. extension
Answer : A

7. Beside renal excretion of sodium, what does atrial natriuretic hormone cause?
A. constriction of renal afferent arterioles
B. renin inhibition
C. aldosterone stimulation
D. rise in systemic blood pressure
Answer : B

8. Which area in the nervous system is tested by bulbocavernosus reflex?
A. brain stem
B. C2 C4
C. S2 - S4
D. L2 - L4
Answer : C

9. Which of the following is false regarding Addison`s disease?
A. autoimmune disease in 70% of the cases
B. diagnosed by the rapid ACTH stimulation test
C. characterized by low serum sodium and high potassium
D. may coexist with hyperthyroidism and diabetes mellitus
Answer : D

10. Between which 2 fascial planes does the prostatic neurovascular bundle travel?
A. prostatic fascia and levator fascia
B. prostate capsule and prostatic fascia
C. Denonvilliers fascia and prostate capsule
D. Denonvilliers fascia and endopelvic fascia
Answer : A

11. Regarding multicystic kidneys, at what age does the compensatory renal growth end?
A. at birth
B. 2 years
C. at puberty
D. none of the above
Answer : B

12. What is false concerning PSA molecule?
A. the free form of PSA exists in small proportions in the body, and found mainly in BPH and in the ejaculate
B. ?1- anti chymotrypsin binds to 3 epitopes of the PSA molecule to form a complexed PSA
C. ?2- macroglobulin binds to 5 epitopes of the PSA molecule to form a complexed PSA
D. the purified PSA molecule has a molecular weight of 90 kDa
Answer : D

13. What fascial layer(s) cover(s) the prostate?
A. Denonvilliers fascia
B. prostatic fascia
C. levator fascia
D. all of the above
Answer : D

14. During fluoroscopy, what is the main source of radiation hazards that urologists could be exposed to?
A. scattered radiation from the unleaded wall
B. scattered radiation from the patient
C. scattered radiation from the floor and ceiling
D. radiation from the primary beam
Answer : B

15. What is the most likely cause of large scrotal hematoma in neonates?
A. clotting factor VIII deficiency
B. clotting factor IX deficiency
C. breech delivery
D. scrotal cavernous haemangioma
Answer : C

16. Which type of renal tubular acidosis (RTA) is more likely to form renal stones?
A. type 1
B. type 2
C. type 3
D. type 4
Answer : A

17. What class of antibiotics might cause vestibular and/or auditory impairment?
A. aminoglycosides
B. ?antipseudomonal penicillins
C. cephalosporins
D. fluoroquinolones
Answer : A

18. Which drug does NOT result in urinary retention?
A. terazosin, antihypertensive
B. benzodiazepines, psychotropic medicine
C. levodopa, anti-Parkinsonism medicine
D. brimonidine, glaucoma eye drops
Answer : A

19. Which of the following does NOT increase PSA value?
A. trauma to the prostate
B. digital rectal examination
C. urinary retention
D. prostatitis
Answer : B

20. Which of the prostate medications could result in significant hypotension?
A. finasteride
B. prazosin
C. silodosin
D. vardenafil
Answer : B

21. What is true regarding hematospermia?
A. should be investigated thoroughly like hematuria
B. is rarely associated with significant urologic pathology C. carries a risk of infertility
D. mandates testicular biopsy
Answer : B

22. When should a 70 yrs. man with 40 ml prostate volume, and total PSA of 2.0 ng/ml, go for a prostate biopsy?
A. if PSA reading had exceeded 2.7 ng/ml over 12 months
B. if free PSA reading was less than 0.4 ng/ml
C. if total PSA reading was greater than 8 ng/ml
D. any of the above
Answer : D

23. What is false about indinavir sulfate stones?
A. intratubular crystal formation might occur
B. CT cannot reliably confirm the presence of indinavir calculi
C. stone formation is demonstrated in 80% of patients taking the medication
D. is a protease inhibitor with poor solubility and significant urinary excretion
Answer : C

24. Which statement is false concerning capacitation of spermatozoa?
A. occurs after acrosome reaction
B. entails removal of a glycoprotein layer
C. it is a biochemical event of sperm maturation
D. changes occur in the female genital tract
Answer : A

25. Which of the following conditions could result in white urine?
A. chyluria
B. bacteriuria
C. phosphaturia
D. all of the above
Answer : D

26. The commonest neoplasms that metastasize to kidneys come from:
A. breasts
B. thyroids
C. lungs
D. liver
Answer : C

27. What is the appropriate intravenous maintenance fluid for a 16 kg girl?
A. 43 ml/hr of normal saline
B. 78 ml/hr of ¼ normal saline
C. 69 ml/hr of ½ normal saline
D. 54 ml/hr of ¼ normal saline
Answer : D

28. What is false concerning fosfomycin antibiotic?
A. has a limited cross-resistance with most common antibacterial agents
B. causes injection site reactions
C. is active against most uropathogens
D. is effective as a single-dose agent
Answer : B

29. How many renal papillae are there in a typical kidney?
A. 4 to 6
B. 7 to 9
C. 10 to 12
D. 13 to 14
Answer : B

30. Renal blood flow is autoregulated by:
A. sympathetic nervous system
B. parasympathetic nervous system
C. urinary output
D. afferent arteriolar resistance
Answer : D

31. Regarding renal ectopia, usually, the adrenals:
A. are cross ectopic
B. are at their normal position
C. travel with the kidneys
D. undergo ischemic atrophy
Answer : B

32. What causes Cushing`s disease is:
A. bilateral adrenal hyperplasia
B. pituitary over secretion of ACTH
C. exogenous administration of glucocorticoids
D. immune-mediated disease
Answer : B

33. Which type of renal stone crystals is known as coffin lid?
A. oxalate
B. struvite
C. urate
D. cystine
Answer : B

34. What is the earliest clinical sign of puberty in boys?
A. hoarseness of voice
B. enlargement of testes
C. appearance of axillary hair
D. change in body odor
Answer : B

35. Hematuria of glomerular origin is associated with:
A. significant proteinuria, dysmorphic RBCs, RBC casts
B. glycosuria, eumorphic RBCs, WBC casts
C. hypercalciuria, eumorphic RBCs, granular casts
D. proteinuria, dysmorphic RBCs, hyaline casts
Answer : A

36. Which period of intrauterine life does the process of organ formation (organogenesis) take place?
A. 9 12 weeks
B. 12 15 weeks
C. 15 18 weeks
D. 18 21 weeks
Answer : A

37. All of the following develop from the mesonephric ducts, EXCEPT:
A. vas deferens
B. seminal vesicles
C. appendix epididymis
D. appendix testis
Answer : D

38. Which of the prostate medications could result in retrograde ejaculation?
A. tamsulosin
B. doxazosin
C. dutasteride
D. alfuzosin
Answer : A

39. What nerve provides the major neural supply to the striated urinary sphincter and levator ani muscle?
A. somatic innervations
B. sympathetic fibers from T11 - L2
C. the pudendal nerve
D. the obturator nerve
Answer : C

40. What are the posterior relations of the kidneys?
A. quadratus lumborum and diaphragm
B. psoas and diaphragm
C. psoas and latissimus dorsi
D. transversus abdominus and paraspinous
Answer : A

41. What could render red urine workup, false positive for hematuria?
A. dehydration
B. myoglobinuria
C. high doses of vitamin C
D. all of the above
Answer : D

42. At what month of intra-uterine life do testes descend into the scrotum with the aid of the intra-abdominal pressure and the gubernacula?
A. sixth
B. seventh
C. eighth
D. ninth
Answer : B

43. Which zone of the prostate originates from the Wolffian duct tissue:
A. central zone
B. peripheral zone C. transitional zone
D. periurethral glands
Answer : A

44. What is the best initial therapy for hyponatremic dehydration?
A. administration of hypertonic saline
B. administration of crystalloid
C. administration of normal saline
D. administration of ringer lactate
Answer : C

45. Which of the following might cause sterile pyuria?
A. renal tuberculosis
B. urinary tract stones
C. interstitial cystitis
D. all of the above
Answer : D

46. In males, which of the following structure(s) can NOT be palpated during digital rectal examination?
A. pelvic floor muscles
B. seminal vesicles
C. anterior surface of the sacrum
D. median lobe of the prostate
Answer : D

47. Which agent is safe to kidneys?
A. amoxicillin
B. gentamycin
C. diclofenac
D. herb extract
Answer : A

48. What is false concerning the collecting system structures of a typical kidney?
A. the renal pelvis could be intra or extra renal
B. the renal pelvis divides into 2 or 3 major calyces
C. major calyces divide into 2 or 3 minor calyces
D. unlike lateral calyces, polar calyces are often paired
Answer : D

49. Which part of the prostate prevents the seminal fluid from entering the bladder during ejaculation?
A. central zone
B. peripheral zone
C. preprostatic tissue
D. anterior fibromuscular stroma
Answer : C

50. What is the number of bacteria per high-power field microscopy that matches colony counts of 100,000/mL?
A. 100
B. 50
C. 10
D. 5
Answer : D