Urologic infections and inflammations 1000+ MCQ with answer for FCI Recruitment

1. Which of the following is NOT a treatment option for BPS/IC?
A. substitution cystoplasty and continent diversion
B. fulguration of a Hunner`s ulcer or hydrodistention
C. intravesical installation of silver nitrate or dimethyl sulfoxide
D. low dose external beam irradiation
Answer : D

2. What are the sequelae of recurrent uncomplicated UTI in young women?
A. minimal
B. chronic persistent infections
C. chronic relapsing infections
D. bouts of chronic pyelonephritis
Answer : A

3. What is the commonest cause of relapsing UTI in males?
A. chronic epididymitis
B. epididymo-orchitis
C. chronic bacterial prostatitis
D. venereal cysto-urethritis
Answer : C

4. What is false concerning post UTI renal scarring in pediatrics?
A. the incidence of scarring following a single episode of febrile UTI is 4.5%
B. intra-renal reflux is common in convex papillae
C. scarring and chronic pyelonephritis lead to hypertension in 10-20%
D. scarring is best detected and followed up by DMSA
Answer : B

5. What is true concerning the treatment of catheter associated bacteriuria?
A. should be flushed frequently, but no antibiotic is advised
B. should be treated if febrile UTI has developed
C. should be treated only if urine culture is positive
D. should be treated once the catheter is removed
Answer : B

6. What is false regarding urethral syndrome in postmenopausal women?
A. pH of vaginal secretions increases after menopause
B. estrogen deficiency manifests as trophic urethritis and atrophic vaginitis
C. topical conjugated estrogen replacement carries a significant risk of breast and endometrial cancers
D. manifestations might include obstructive symptoms and non-infectious cystitis
Answer : C

7. What is true regarding urinary catheter-associated UTI (CAUTI)?
A. indwelling catheter insertion must be under sterile condition
B. systemic antibiotics help best in preventing bacteriuria
C. greater than 90% of nosocomial UTIs are related to urethral catheters
D. Intermittent catheterization carries the incidence of 1-3% of developing bacteriuria per insertion
Answer : D

8. What is false concerning acute pyelonephritis?
A. CBC reveals leucocytosis with predominance of neutrophils
B. contrast CT reveals one or more focal wedge-like swollen regions of the kidney parenchyma, sparing the cortex, and demonstrating reduced enhancement rim sign
C. in children, recurrent acute pyelonephritis might lead to renal scarring
D. in pregnancy, recurrent acute pyelonephritis might lead to preterm labor
Answer : B

9. Which of the following factors increases the risk of UTI due to promotion of microbial colonization?
A. neurogenic bladder
B. the use of spermicide
C. urinary catheterization
D. fecal incontinence
Answer : B

10. What is false regarding biopsy-taking from interstitial cystitis bladder?
A. no pathognomonic histology for interstitial cystitis
B. basically, biopsies are performed to exclude carcinomas and other varieties of cystitis
C. diagnostic biopsies include the presence of discrete micro-ulcers and increased numbers of mast cells in the detrusor muscle or submucosa
D. none of the above
Answer : C

11. What is true regarding honeymoon cystitis?
A. is a self-limiting infection where antibiotics are not required
B. is exclusively for UTI experienced by a girl after sexual intercourse on her wedding night
C. post-coital voiding has no value in the occurrence of the infection
D. self-initiated medication helps control the infection
Answer : D

12. What is (are) the cause(s) of recurrent community acquired UTI in women?
A. uncontrolled DM
B. sexual activity with multiple partners
C. high vaginal receptivity to bacterial adherence
D. all of the above
Answer : D

13. What is true concerning ovarian vein syndrome?
A. manifests as recurrent renal colics due to ureteral obstruction
B. treatment is surgical mobilization of ureter and ligation of the vein
C. commonly, occurs at the left side
D. the pain worsens on sitting upright and during pregnancy
Answer : B

14. What is true regarding Xanthogranulomatous Pyelonephritis?
A. CT shows the characteristic bear paw sign
B. it is an infected, obstructed, poorly functioning kidney containing stones
C. nephrectomy is the treatment
D. all of the above
Answer : D

15. Histologically, the pathognomonic finding of Fournier gangrene include:
A. necrosis of the superficial and deep fascial planes
B. fibrinoid thrombosis of the nutrient arterioles
C. polymorphonuclear cell infiltration
D. all of the above
Answer : D

16. What is false concerning genitourinary TB?
A. is the commonest extra-pulmonary site of infection
B. bladder TB is secondary to renal TB, and usually begins at the ureteral orifices
C. in the kidneys, TB is typically bilateral, cortical, and adjacent to the glomeruli; they may remain dormant for ages
D. epididymal TB might occur by hematogenous or direct spread from the urinary tract
Answer : A

17. UPOINT system for phenotype categorization:
A. categorizes CP-CPPS, IC, and painful bladder sydrome based on 5 etiological principles
B. meant to classify CP-CPPS and IC patients into 6 domains
C. helps establish a reliable diagnosis of CP/CPPS or IC
D. the diagnostic scores of UPOINT depend on cystoscopy, TRUS, urine analysis and culture of uncommon microbes
Answer : B

18. Which of the following conditions is NOT associated with interstitial cystitis?
A. inflammatory bowel disease
B. rheumatoid arthritis
C. systemic lupus erythematosus
D. fibromyalgia
Answer : B

19. What is false in the treatment and prevention of STDs?
A. antibiotic therapy is recommended for affected individuals with documented trichomonal infection and sexual partners even if asymptomatic
B. empirical treatment for gonococcal urethritis should cover chlamydia trachomatis
C. consistent and proper usage of condoms is estimated to prevent HIV transmission by approximately 80 to 95%
D. vaccinations are available for the prevention of human papillomavirus, N. gonorrhea, chlamydia trachomatis
Answer : D

20. What is false regarding malakoplakia?
A. is an uncommon granulomatous disease that affect the skin and/or urinary bladder
B. it might be due to a disturbed function of B lymphocytes
C. characterized by the presence of basophilic inclusion structure (Michaelis-Gutmann body)
D. it might be due to a defective phagolysosomal activity of monocytes or macrophages
Answer : B

21. What is false concerning foreign body cystitis?
A. most commonly due to indwelling catheters
B. the areas of inflammation are usually confined to the lateral walls or the dome of the bladder
C. radiographic changes are nonspecific or present as bullous edema
D. indwelling catheters are associated with squamous cell carcinoma of the bladder
Answer : B

22. Using low-dose prophylactic or suppressive antimicrobials might be an option in treating the following type of prostatitis:
A. acute bacterial prostatitis presenting with abscess formation
B. recurrent or refractory chronic bacterial prostatitis
C. asymptomatic prostatitis with pyuria resistant to common antimicrobials
D. curiously, chronic inflammatory prostatitis could respond to low-dose suppressive antibiotic
Answer : B

23. Under which surgical wound classification, does diagnostic cystoscopy under sterile technique fit?
A. dirty - infected
B. contaminated
C. clean - contaminated
D. clean
Answer : C

24. What is the most significant biological difference in women susceptibility to UTI?
A. adherence of bacteria to vaginal cells
B. vaginal dryness
C. O serogroup
D. vaginal pH
Answer : A

25. What is the bladder`s first-line defense against infections?
A. natural sloughing of bladder mucosa
B. voiding
C. urine osmolarity
D. urine pH
Answer : B

26. What kind of cystitis does NOT progress to malignancy?
A. foreign-body cystitis due to vesical calculi
B. Von Brunn`s nests of cystitis cystica and cystitis glandularis
C. schistosomiasis cystitis
D. inverted papilloma of the bladder
Answer : B

27. What is false concerning chronic orchialgia syndrome?
A. it is a constant or intermittent pain of testes for more than 3 months
B. could be due to appendix testis torsion-detorsion
C. could be due to radiculitis resulting from a degenerative lesion in the thoraco-lumber vertebrae
D. could be a result of entrapment neuropathy of ilioinguinal or genitofemoral nerve
Answer : B

28. What is the most significant complication of papillary necrosis?
A. ureteral obstruction
B. proteinuria
C. stone formation
D. renal scarring
Answer : A

29. What is false concerning Brucellosis epididymitis?
A. commonly presents with scrotal pain, swelling, fever, and leucocytosis
B. epididymo-orchitis is the most frequent genitourinary complication of brucellosis
C. epididymo-orchitis occurs in 10-15% of male patients with brucellosis
D. treatment includes doxycycline and rifampicin for 6-8 weeks
Answer : A

30. What type of cells is implicated most in the pathogenesis of BPS/IC?
A. histocytes
B. T lymphocytes
C. mast cells
D. B lymphocytes
Answer : C

31. What is the ideal antibiotic class for self-start therapy on treating recurrent cystitis in a 32 yrs. married woman?
A. aminopenicillins
B. fluoroquinolones
C. aminoglycosides
D. nitrofurantoins
Answer : B

32. What is false concerning sepsis syndrome?
A. poor tissue perfusion manifests as hyperlactemia and decreased capillary refill
B. acute oliguria indicates an organ dysfunction and circulatory collapse
C. septic shock is an extreme form of sepsis when hypotension persists despite adequate fluid resuscitation
D. hypotension is a sign of hyperdynamic circulation at an early septic shock
Answer : D

33. What is true concerning the definition of UTI in women, based on culture results from a suprapubic aspirate of urine?
A. any amount of uropathogen grown in culture indicates UTI
B. for cystitis, more than 1000 CFU/mL indicates UTI
C. for pyelonephritis, more than 10,000 CFU/mL indicates UTI
D. for asymptomatic bacteriuria, more than 100,000 CFU/mL indicates UTI
Answer : A

34. What is the most common serotype of HPV associated with squamous cell carcinoma of the penis?
A. 16
B. 18
C. 22
strong>D. 12
Answer : A

35. What is (are) the complication(s) of sexually transmitted infections?
A. pelvic inflammatory disease
B. lymphogranuloma venereum
C. infertility
D. all of the above
Answer : D

36. What could cause scrotal sinus?
A. improperly drained hair follicle scrotal abscess
B. syphilitic orchitis
C. tuberculous epididymitis
D. all of the above
Answer : D

37. What is the least important measure in indwelling catheter care?
A. cleansing the urethral meatus with aseptic agent
B. careful aseptic insertion of the catheter
C. maintenance of a closed drainage system
D. maintaining a dependant drainage system
Answer : A

38. What type of human Herpes virus is implicated in all forms of Kaposi sarcoma?
A. 2
B. 6
C. 7
D. 8
Answer : D

39. What is NOT a complication of mumps orchitis?
A. infertility
B. hypogonadotropic hypogonadism
C. non seminomatous germ cell tumor
D. chronic orchalgia
Answer : C

40. What does NOT predispose to acute epididymitis is:
A. TUR ejaculatory duct
B. prolonged urethral catheterization
C. prostatic biopsy
D. vas ligation
Answer : C

41. What is the mortality rate of emphysematous pyelonephritis?
A. 43%
B. 53%
C. 63%
D. 73%
Answer : A

42. What is false concerning emphysematous cystitis?
A. the hallmark in the diagnosis is the cystoscopic findings
B. risk factors include transplant recipients
C. CT shows intramural and/or intraluminal gas in the bladder
D. requires surgical debridement and probably cystectomy
Answer : A

43. What condition(s) could occur in schistosomal ureter?
A. beading of the lower ureteral segment
B. ureteral fibrosis and calcifications of the distal ureter
C. stricture at the uretero-vesical junction
D. all of the above
Answer : D

44. What is false concerning antiretroviral medications?
A. multiple antiretroviral drugs can be combined into a single pill
B. might cause radiolucent renal stones
C. can lead to a significant rise in the serum level of PDE5 inhibitors, if taken simultaneously
D. have the advantage of structured treatment interruptions (drug holidays)
Answer : D

45. A 40 yrs. man presents with clinical acute pyelonephritis, on intravenous antibiotics for 4 days, CT shows a renal abscess. What is next in the treatment?
A. carry on the full antibiotic course, and then repeat CT
B. incision and drainage of the renal abscess with/without nephrectomy
C. the abscess size dictates management
D. perc. drainage of the renal abscess
Answer : C

46. What is (are) the prominent clinical finding(s) in the diagnosis of acute pyelonephritis?
A. fever, chills, abdominal pain
B. costovertibral angle tenderness
C. hypogastric and loin pain
D. flank pain, dysuria
Answer : B

47. What is the most important pharmacokinetic property of a drug to cure UTI?
A. mode of administration
B. level in the serum
C. level in the urine
D. dosage
Answer : C

48. When comparing nosocomial to community-acquired UTI, the latter is:
A. 45% are caused by E. coli
B. related to an indwelling urinary catheter in approximately 40% of cases
C. responds fairly to oral antibiotics
D. tends to report higher antibiotic resistance
Answer : C

49. What group of patients should be treated for UTI only when symptomatic?
A. patients with indwelling catheters
B. neurogenic bladder patients on CIC
C. pregnant women
D. children under 5 years
Answer : A

50. What is true regarding genitourinary TB?
A. commonly, TB enters the urinary tract via intravesical instillation of attenuated live BCG to treat bladder cancer
B. CT urography may show infundibular stricture with or without hydrocalicosis
C. renal ultrasonography reveals calyceal erosions moth-eaten calyx
D. TB of the vas appears, clinically, as a thin hard strictured tube
Answer : B