Urologic infections and inflammations 1000+ MCQ with answer for UPSC IES

1. What is the most important pharmacokinetic property of a drug to cure UTI?
A. mode of administration
B. level in the serum
C. level in the urine
D. dosage
Answer : C

2. What virus(s) could cause orchitis?
A. Coxsackie B
B. Epstein-Barr
C. varicella
D. all of the above
Answer : D

3. What is true concerning ovarian vein syndrome?
A. manifests as recurrent renal colics due to ureteral obstruction
B. treatment is surgical mobilization of ureter and ligation of the vein
C. commonly, occurs at the left side
D. the pain worsens on sitting upright and during pregnancy
Answer : B

4. When comparing nosocomial to community-acquired UTI, the latter is:
A. 45% are caused by E. coli
B. related to an indwelling urinary catheter in approximately 40% of cases
C. responds fairly to oral antibiotics
D. tends to report higher antibiotic resistance
Answer : C

5. During the initial 3-month period of HIV infection, what would be the best diagnostic lab test?
A. viral load assay
B. western blot analysis
C. southern blot analysis
D. HIV-1/HIV-2 serology assay
Answer : A

6. What is false concerning esinophilic cystitis?
A. probably due to antibody/antigen reaction
B. has no diagnostic findings on cystoscopy
C. has no specific medical therapy
D. on histology, Von Brunn`s nests appear invaginating the urothelium into the lamina propria
Answer : D

7. What is false concerning the management of genitourinary TB?
A. prostatic TB is better drained per rectum before initiating the medications
B. renal TB may require nephroureterectomy
C. peripheral neuritis is a known side effect of isoniazid
D. moxifloxacin might result in tendon rupture
Answer : A

8. What is false concerning the presentation of prostatitis syndrome?
A. type I could harbor prostate abscess
B. type II presents as intermittent urinary tract infections
C. type III-a presentation might include psychological complaints
D. between 10-15% of men with type IV, have pus cells in their semen but no symptoms
Answer : C

9. What is false concerning peri-renal abscess?
A. could result from intra-renal abscess of ascending infection
B. urine culture might be negative
C. plain KUB X-ray has no value in the diagnosis
D. surgical drainage is the proper treatment
Answer : C

10. What is false in the treatment and prevention of STDs?
A. antibiotic therapy is recommended for affected individuals with documented trichomonal infection and sexual partners even if asymptomatic
B. empirical treatment for gonococcal urethritis should cover chlamydia trachomatis
C. consistent and proper usage of condoms is estimated to prevent HIV transmission by approximately 80 to 95%
D. vaccinations are available for the prevention of human papillomavirus, N. gonorrhea, chlamydia trachomatis
Answer : D

11. What is false concerning cystitis glandularis?
A. rarely, the urothelial cell nests show a central lumen lined by glandular epithelium
B. In some cases, it may form polypoid masses that mimic urothelial neoplasms
C. It might appear as multinodular exophytic mass seen on cystoscopy
D. cystitis cystica and cystitis glandularis frequently coexist in the same specimen
Answer : A

12. What is false concerning epididymitis?
A. should be distinguished from testicular torsion in the emergency setting
B. viral epididymitis is commoner in the elderly
C. chronic epididymitis might complicate BPH
D. chronic epididymitis might require epididymectomy
Answer : B

13. What is NOT a poor clinical practice on caring for urethral catheters?
A. taking urine samples by draining the urine bag
B. daily cleansing the external meatus
C. placing the urine bag on the floor
D. changing the urine bag once it is full
Answer : B

14. What are the target immune cells for HIV?
A. phagocytes
B. CD4 T cells
C. B lymphocytes
D. natural killer cells
Answer : B

15. What is the ideal antibiotic class for self-start therapy on treating recurrent cystitis in a 32 yrs. married woman?
A. aminopenicillins
B. fluoroquinolones
C. aminoglycosides
D. nitrofurantoins
Answer : B

16. What is false concerning genitourinary TB?
A. is the commonest extra-pulmonary site of infection
B. bladder TB is secondary to renal TB, and usually begins at the ureteral orifices
C. in the kidneys, TB is typically bilateral, cortical, and adjacent to the glomeruli; they may remain dormant for ages
D. epididymal TB might occur by hematogenous or direct spread from the urinary tract
Answer : A

17. Directed physiotherapy could be of value in treating what NIH type of prostatitis?
A. type II
B. type III-a
C. type III-b
D. type IV
Answer : C

18. What is false concerning urinary catheter-associated UTI (CAUTI)?
A. once a catheter is placed, the daily incidence of bacteriuria is 3-10%
B. on long-term catheterization, over 90% of patients develop bacteriuria
C.the practice of using urinary catheters to control incontinence in bedridden patients should be discouraged
D. urine bags should be placed on the floor to enhance gravity drainage
Answer : D

19. What is true concerning scrotal abscesses?
A. could be a complication of chronic epididymitis and orchalgia
B. testicular torsion must be excluded
C. infected hair follicles and scrotal lacerations are predisposing factors
D. urethral discharge is not uncommon presentation
Answer : C

20. What is true regarding chronic epididymitis symptomatology?
A. pain is dull aching in the scrotum, perineum, inner thighs, and lower abdomen
B. dysuria, frequency, and/or urgency
C. long-standing (> 6 weeks) history of scrotal pain, and tenderness
D. low grade fever, malaise, and urethral discharge
Answer : C

21. What is false concerning Chlamydia trachomatis urethritis in males:
A. produces yellow whitish, scanty, frothy urethral discharge
B. shows gram (+), extracellular diplococcic
C. infection could be contracted from the spouses eyes
D. responds fairly to azithromycin
Answer : B

22. What is false concerning post UTI renal scarring in pediatrics?
A. the incidence of scarring following a single episode of febrile UTI is 4.5%
B. intra-renal reflux is common in convex papillae
C. scarring and chronic pyelonephritis lead to hypertension in 10-20%
D. scarring is best detected and followed up by DMSA
Answer : B

23. What is false concerning HIV infection?
A. AIDS patients in active infection show low CD4 + T-cell count
B. the diagnosis is confirmed by positive anti-HIV-1, anti-HIV-2 antibodies
C. patients receiving antiviral therapy could still be infectious
D. herpes simplex virus increases HIV replication in infected persons
Answer : B

24. Which of the following does NOT cause unresolved bacteriuria?
A. giant staghorn stone
B. perivesical abscess with fistula to the bladder
C. bacterial resistance
D. self-inflicted infection
Answer : B

25. Patients with bladder pain syndrome have:
A. a history of repeated urologic and/or gynecologic procedures
B. 10 fold higher incidence of childhood voiding problems
C. 4 fold higher incidence of anxiety-depression syndrome
D. 6 fold higher incidence of psychosomatic disorders
Answer : B

26. What is true concerning HIV infection?
A. HIV is a retrovirus that infects B-cells and dendritic cells
B. circumcised men are at lower risk for HIV infection
C. HPV infection increases the risk for cancers in HIV patients by 6.3 times
D. plasma HIV RNA load is a predictor of disease remission
Answer : B

27. What is the estimated risk of untreated Chlamydial infections in producing pelvic inflammatory disease?
A. 1 2.7%
B. 5 9%
C. 10 27%
D. 30 47%
Answer : C

28. What is true concerning the definition of UTI in women, based on culture results from a suprapubic aspirate of urine?
A. any amount of uropathogen grown in culture indicates UTI
B. for cystitis, more than 1000 CFU/mL indicates UTI
C. for pyelonephritis, more than 10,000 CFU/mL indicates UTI
D. for asymptomatic bacteriuria, more than 100,000 CFU/mL indicates UTI
Answer : A

29. What is the laboratory differentiation between type III-a and type III-b prostatitis?
A. the cytological examination of the urine and/or EPS
B. transrectal ultrasonographic examination
C. the presence of ?10 WBCs/HPF in the urine with negative culture in type III-b
D. the positive urine culture, and negative EPS support type III-a
Answer : A

30. What is false regarding viral cystitis?
A. in pediatrics, adenovirus types 11 and 21 could result in hemorrhagic cystitis
B. immunosuppressed children are especially susceptible to Cytomegalovirus and Adenoviruses 7, 21, and 35
C. in pediatrics, acute viral cystitis might present as acute retention of urine
D. classically, treatment should be culture-specific
Answer : D

31. Which of the following factors increases the risk of UTI due to promotion of microbial colonization?
A. neurogenic bladder
B. the use of spermicide
C. urinary catheterization
D. fecal incontinence
Answer : B

32. What is false concerning radiation cystitis?
A. the average time from the beginning of radiation therapy to initial symptoms could be 2 4 weeks
B. treatment with stationary radiation, portals carry a higher risk of morbidity than treatment with rotating portals do
C. it occurs in about 10% of patients treated with definitive irradiation therapy for prostate cancer after 10 years
D. most cases are mildly affected and require no specific therapy
Answer : A

33. Which treatment modality has NO proven efficacy in CP/CPPS?
A. selective nerve block
B. balloon dilation
C. botulinum A toxin injection
D. ESWL
Answer : B

34. What is the earliest clinical finding of urosepsis?
A. elevated body temperature
B. dropped blood pressure
C. elevated heart rate
D. reduced urine output
Answer : C

35. As per NIH classification of prostatitis, which type requires no treatment?
A. type I
B. type II
C. type III
D. type IV
Answer : D

36. Ureteral dilation in schistosomiasis could be due to:
A. vesicoureteral reflux
B. stenosis of the lower ureter
C. edematous ureteral wall causing deficient peristalsis
D. any of the above
Answer : D

37. What is false regarding malakoplakia?
A. is an uncommon granulomatous disease that affect the skin and/or urinary bladder
B. it might be due to a disturbed function of B lymphocytes
C. characterized by the presence of basophilic inclusion structure (Michaelis-Gutmann body)
D. it might be due to a defective phagolysosomal activity of monocytes or macrophages
Answer : B

38. What is the commonest intra-scrotal pathology in AIDS patients?
A. beaded vas deferens
B. testicular micrilithiasis
C. testicular atrophy
D. epididymal granuloma
Answer : C

39. What is the least important measure in indwelling catheter care?
A. cleansing the urethral meatus with aseptic agent
B. careful aseptic insertion of the catheter
C. maintenance of a closed drainage system
D. maintaining a dependant drainage system
Answer : A

40. In which segmented voided bladder (VB) specimen, the diagnosis of chronic prostatitis is confirmed?
A. VB1 and VB3
B. prostatic secretions and the VB3
C. prostatic secretions and the VB2
D. prostatic secretions and the VB1
Answer : B

41. A 40 yrs. man presents with clinical acute pyelonephritis, on intravenous antibiotics for 4 days, CT shows a renal abscess. What is next in the treatment?
A. carry on the full antibiotic course, and then repeat CT
B. incision and drainage of the renal abscess with/without nephrectomy
C. the abscess size dictates management
D. perc. drainage of the renal abscess
Answer : C

42. What is false regarding biopsy-taking from interstitial cystitis bladder?
A. no pathognomonic histology for interstitial cystitis
B. basically, biopsies are performed to exclude carcinomas and other varieties of cystitis
C. diagnostic biopsies include the presence of discrete micro-ulcers and increased numbers of mast cells in the detrusor muscle or submucosa
D. none of the above
Answer : C

43. What is false concerning Brucellosis epididymitis?
A. commonly presents with scrotal pain, swelling, fever, and leucocytosis
B. epididymo-orchitis is the most frequent genitourinary complication of brucellosis
C. epididymo-orchitis occurs in 10-15% of male patients with brucellosis
D. treatment includes doxycycline and rifampicin for 6-8 weeks
Answer : A

44. What is true concerning granulomatous inflammation of the prostate?
A. is a common cause of elevated PSA level
B. might follow BCG treatment
C. is sequelae of untreated type III-b prostatitis
D. shows homogenous enhancement following Gd-DTPA on prostate MRI
Answer : B

45. Which of the following is NOT a first-choice antimicrobial agent for uncomplicated acute cystitis in women?
A. nitrofurantoin monohydrate/macrocrystals
B. trimethoprim-sulfamethoxazole
C. ampicillin
D. fosfomycin
Answer : C

46. What type of cells is implicated most in the pathogenesis of BPS/IC?
A. histocytes
B. T lymphocytes
C. mast cells
D. B lymphocytes
Answer : C

47. What is false regarding Herpes simplex (HSV) infection?
A. characterized by neurovirulence
B. the incubation period of primary genital herpes is 2 3 weeks
C. HSV can be isolated in the urine
D. HSV-1 infection causes urethritis more often than HSV-2 does
Answer : B

48. What is false regarding prostatic abscesses?
A. clinically, cannot be differentiated from acute bacterial prostatitis
B. medical management is often unsuccessful
C. it harbors prostate cancer in approximately 4.3% of cases
D. management include suprapubic urinary diversion
Answer : C

49. What is the most significant complication of papillary necrosis?
A. ureteral obstruction
B. proteinuria
C. stone formation
D. renal scarring
Answer : A

50. What is false regarding urethral syndrome in postmenopausal women?
A. pH of vaginal secretions increases after menopause
B. estrogen deficiency manifests as trophic urethritis and atrophic vaginitis
C. topical conjugated estrogen replacement carries a significant risk of breast and endometrial cancers
D. manifestations might include obstructive symptoms and non-infectious cystitis
Answer : C