Urology Basic Science MCQ Solved Paper for RRB JE

1. What is the nature of the prostate-specific antigen?
A. protease
B. lyase
C. carboxylase
D. hydrolase
Answer : A

2. What degrades semenogelin and determines the consistency of the seminal coagulum is:
A. spermine
B. acid phosphatase
C. PSA
D. semenoglobulin
Answer : C

3. Which class of the following agents does NOT impair spermatogenesis?
A. alkylating agents
B. phenothiazines
C. antiandrogens
D. prostaglandins
Answer : B

4. Which of the following is (are) direct branch(es) of the abdominal aorta?
A. median sacral artery
B. inferior phrenic arteries
C. gonadal arteries
D. all of the above
Answer : D

5. Which statement explains the first event in the micturition reflex?
A. opening of internal bladder sphincter
B. fall in urethral pressure
C. rise in intravesical pressure
D. cessation of sphincter EMG activity
Answer : D

6. What is the half-life of ?-HCG?
A. 5 7 days
B. 24 36 hours
C. 2 3 days
D. 12 24 hours
Answer : B

7. Which organ contributes most to the seminal fluid volume?
A. testes
B. prostate
C. seminal vesicles
D. bulbourethral glands
Answer : C

8. Branches of what artery travel under the endopelvic fascia form the prostate to the sidewall of the pelvis?
A. obturator artery
B. midrectal artery
C. inferior vesical artery
D. pudendal artery
Answer : D

9. Which of the following contributes second to the seminal fluid by volume?
A. seminal vesicles
B. the prostate
C. testes
D. bulbourethral glands
Answer : B

10. Which of the following process(es) is (are) reversible?
A. 5?-reductase enzyme reduces testosterone to DHT
B. aromatase enzyme reduces testosterone to estrogen
C. PSA molecule binds to ?1-antichymotrypsin and ?2-macroglobulin
D. none of the above
Answer : D

11. Which of the following does asymptomatic hematuria workup include?
A. cystoscopy
B. CT urography
C. urine cytology
D. all of the above
Answer : D

12. How many renal papillae are there in a typical kidney?
A. 4 to 6
B. 7 to 9
C. 10 to 12
D. 13 to 14
Answer : B

13. What is the most frequent anomaly associated with multicystic renal dysplasia?
A. ureteral atresia
B. vesicoureteral reflux
C. ureteropelvic junction obstruction
D. ureteral duplication
Answer : A

14. What are the first and second most common zones from where prostate cancers arise?
A. central then transitional
B. peripheral then transitional
C. peripheral then central
D. transitional then central
Answer : B

15. Where is Santorini plexus located?
A. at either side of the prostate
B. in the pubo-prostatic space
C. anterior to the seminal vesicles
D. posterior to the vaso-epididymal junction
Answer : B

16. Regarding multicystic kidneys, at what age does the compensatory renal growth end?
A. at birth
B. 2 years
C. at puberty
D. none of the above
Answer : B

17. Serum testosterone should be measured:
A. at mid-day
B. at the hour of sleep
C. in the morning
D. late afternoon
Answer : C

18. What are the posterior relations of the kidneys?
A. quadratus lumborum and diaphragm
B. psoas and diaphragm
C. psoas and latissimus dorsi
D. transversus abdominus and paraspinous
Answer : A

19. What does apoptosis mean?
A. programmed cell death
B. new vascular formation
C. uninhibited neural stimulation
D. premature muscular contraction
Answer : A

20. Which of the following conditions could result in white urine?
A. chyluria
B. bacteriuria
C. phosphaturia
D. all of the above
Answer : D

21. What are the abnormalities that might accompany complete ureteral duplications?
A. reflux to the upper pole ureter, obstruction to the lower pole ureter
B. reflux to the lower pole ureter, obstruction to the upper pole ureter
C. left ureteropelvic junction obstruction, right ureterocele
D. right ureteropelvic junction obstruction, left ureterocele
Answer : B

22. What causes pink diaper syndrome is (are):
A. Staphylococcus epidermidis in the urine
B. dried urate crystals on the diaper
C. Adenovirus 11 in the urine
D. Candidiasis in the urine
Answer : B

23. At which type of renal tubular acidosis (RTA), typiclly, potassium levels increase?
A. type 1
B. type 2
C. type 3
D. type 4
Answer : D

24. Between which 2 fascial planes does the prostatic neurovascular bundle travel?
A. prostatic fascia and levator fascia
B. prostate capsule and prostatic fascia
C. Denonvilliers fascia and prostate capsule
D. Denonvilliers fascia and endopelvic fascia
Answer : A

25. Which of the prostate medications could result in significant hypotension?
A. finasteride
B. prazosin
C. silodosin
D. vardenafil
Answer : B

26. What is the most likely cause of large scrotal hematoma in neonates?
A. clotting factor VIII deficiency
B. clotting factor IX deficiency
C. breech delivery
D. scrotal cavernous haemangioma
Answer : C

27. What is the most significant innervation of the vas deferens?
A. sympathetic nervous system
B. parasympathetic nervous system
C. somatic nervous system
D. none of the above
Answer : A

28. Which disease is described best by the following manifestations: grand mal epilepsy, mental retardation, hypertension, angiomyolipoma, adenoma sebaceum, bilateral enlarged kidneys, and normal renal function?
A. autosomal dominant polycystic kidney disease
B. von Hippel-Lindau disease
C. tuberous sclerosis
D. Sturge-Webber syndrome
Answer : C

29. Which of the renal artery occlusive conditions, commonly, do NOT affect renal function?
A. intimal fibroplasia
B. medial fibroplasia
C. medial hyperplasia
D. serosal hyperplasia
Answer : B

30. Which of the following hormones, primarily, controls spermatogenesis?
A. GnRH
B. testosterone
C. LH
D. FSH
Answer : B

31. Where do Cowper`s gland ducts drain into?
A. ejaculatory ducts
B. prostatic urethra
C. membranous urethra
D. bulbous urethra
Answer : D

32. What type of renal tubular acidosis (RTA) does demonstrate aldosterone resistance?
A. type 1
B. type 2
C. type 3
D. type 4
Answer : D

33. Bacterial resistance to antibiotics may occur because of:
A. inherited chromosomal-mediated resistance
B. acquired chromosomal-mediated resistance
C. extrachromosomal-mediated resistance
D. all of the above
Answer : D

34. What do urine tests examine to detect hematuria?
A. catalase activity of erythrocytes
B. peroxidase activity of erythrocytes
C. lyase activity of erythrocytes
D. none of the above
Answer : B

35. What causes pure testicular feminization is:
A. over estrogen synthesis
B. defective end-organ androgen response
C. extra X chromosome (XXY)
D. failure of genital ridge regression
Answer : B

36. Which of the following conditions could happen in chronic pancreatitis and malabsorption syndrome with steatorrhea?
A. hyperoxaluria
B. hypercalciuria
C. hyperuricosuria
D. hyperphosphateuria
Answer : A

37. The manifestations of autonomic dysreflexia include:
A. hypotension and tachycardia
B. hypotension and bradycardia
C. hypertension and tachycardia
D. hypertension and bradycardia
Answer : D

38. Which ?- adrenergic receptor subtype mediates smooth muscle contraction of the prostate?
A. ?1-A
B. ?2-A
C. ?1-B
D. ?2-B
Answer : A

39. What is the narrowest part of the ureter?
A. uretero-pelvic junction
B. uretero-vesical junction
C. where ureters cross the pelvic brim
D. where ureters cross the common iliac bifurcation
Answer : B

40. What is the function of PSA in semen?
A. increases semen volume
B. has antimicrobial activity
C. liquefies the seminal coagulum
D. decreases semen pH
Answer : C

41. Which nephron segment contains the most diluted urine in central diabetes insipidus patient?
A. proximal convoluted tubules
B. distal convoluted tubules
C. collecting duct
D. loop of Henle
Answer : C

42. Which statement is false concerning the gubernaculua?
A. degenerate after birth
B. called the caudal genital ligaments
C. help guide the testes down through the inguinal canals
D. represent undifferentiated mesenchyme
Answer : A

43. Which class of the following diuretics could cause erectile dysfunction?
A. loop diuretics
B. thiazide diuretics
C. potassium sparing diuretics
D. osmotic diuretics
Answer : B

44. Which statement concerning urine pH is false?
A. influenced by food and medications
B. renal stones form at the extremes of pH range
C. reliable only when measured by 24 hr. urine collection
D. ranges from 4 7
Answer : C

45. Which organism is capable of proliferation in the urin and causing urethritis?
A. Ureaplasma urealyticum
B. Chlamydia trachomatis
C. E. coli
D. Neisseria gonorrhea
Answer : A

46. Where is the centre of reflex erection located at?
A. the brain cortex
B. the sacral cord
C. the lumbar cord
D. the hypothalamus
Answer : B

47. Which of the prostate medications could result in retrograde ejaculation?
A. tamsulosin
B. doxazosin
C. dutasteride
D. alfuzosin
Answer : A

48. At what month of intra-uterine life do testes descend into the scrotum with the aid of the intra-abdominal pressure and the gubernacula?
A. sixth
B. seventh
C. eighth
D. ninth
Answer : B

49. What does make UTI more common in mid-aged females than in males?
A. short female urethra
B. pregnancy
C. vaginal colonization with enterobacteria
D. all the above
Answer : D

50. Which type of renal stone crystals is known as coffin lid?
A. oxalate
B. struvite
C. urate
D. cystine
Answer : B