Urology Basic Science MCQ Solved Paper for SSC JE

1. What is the most significant complication of cyclosporine?
A. hepatic toxicity
B. renal toxicity
C. neural toxicity
D. cardiac toxicity
Answer : B

2. Which type of renal stone crystals is known as coffin lid?
A. oxalate
B. struvite
C. urate
D. cystine
Answer : B

3. Regarding multicystic kidneys, at what age does the compensatory renal growth end?
A. at birth
B. 2 years
C. at puberty
D. none of the above
Answer : B

4. In utero, which hormone stimulates the development of the prostate gland?
A. estradiol
B. DHT
C. FSH
D. testosterone
Answer : B

5. Where do Cowper`s gland ducts drain into?
A. ejaculatory ducts
B. prostatic urethra
C. membranous urethra
D. bulbous urethra
Answer : D

6. What is the nature of the prostate-specific antigen?
A. protease
B. lyase
C. carboxylase
D. hydrolase
Answer : A

7. What is the number of bacteria per high-power field microscopy that matches colony counts of 100,000/mL?
A. 100
B. 50
C. 10
D. 5
Answer : D

8. Which anomaly might accompany horseshoe kidneys?
A. ureteropelvic junction obstruction
B. ureterocele
C. ureteral reflux
D. ureteral atresia
Answer : A

9. Which zone of the prostate originates from the Wolffian duct tissue:
A. central zone
B. peripheral zone
C. transitional zone
D. periurethral glands
Answer : A

10. Hematuria of glomerular origin is associated with:
A. significant proteinuria, dysmorphic RBCs, RBC casts
B. glycosuria, eumorphic RBCs, WBC casts
C. hypercalciuria, eumorphic RBCs, granular casts
D. proteinuria, dysmorphic RBCs, hyaline casts
Answer : A

11. What causes pure testicular feminization is:
A. over estrogen synthesis
B. defective end-organ androgen response
C. extra X chromosome (XXY)
D. failure of genital ridge regression
Answer : B

12. All of the following develop from the mesonephric ducts, EXCEPT:
A. vas deferens
B. seminal vesicles
C. appendix epididymis
D. appendix testis
Answer : D

13. Which action of thigh muscles could be impaired if the obturator nerve was injured during endoscopic resection of bladder tumors?
A. adduction
B. abduction
C. flexion
D. extension
Answer : A

14. What is false concerning renal vasculature?
A. there are 4 surgical segments of the kidney, based on the segmental artery distribution
B. along the kidney convexity, there is an avascular plane
C. there are no collaterals between segmental arteries
D. in < 10%, the posterior branch is the first to branch off the renal artery
Answer : D

15. How long post bilateral orchiectomy, will patients be functionally castrated?
A. immediately
B. after 2 hrs.
C. after 12 hrs.
D. after 24 hrs.
Answer : B

16. Where is the centre of reflex erection located at?
A. the brain cortex
B. the sacral cord
C. the lumbar cord
D. the hypothalamus
Answer : B

17. On tracing the IVU dye down, in a dilated ureter, the dilation stops at a level then continues as a normal calibre ureter. What could the pathology be?
A. lower ureteral stricture
B. ureteral valve
C. modified Lich-Gregoire ureteral reimplantation
D. residual dilation of hydroureter
Answer : B

18. What is the prime effect of antidiuretic hormone on kidneys?
A. increase collecting duct permeability
B. increase medullary blood flow
C. decrease cortical blood flow
D. decrease potassium secretion
Answer : A

19. Which statement is false concerning the epididymis?
A. each epididymis can be palpable at the postero-lateral surface of the testis
B. has 3 parts; head, body, and tail
C. new batches of sperms stay in the epididymis around 2 days for maturation
D. shares the same blood supply of the testis
Answer : C

20. What vessels are located in the prostate neurovascular bundle?
A. Watson plexus
B. capsular arteries and veins
C. inferior vesical and midrectal vessels
D. Santorini plexus
Answer : B

21. Which of the following lab results indicates prerenal failure?
A. serum BUN : creatinine > 20
B. urine [Na] < 30 mEq/L
C. Na excretion fraction < 1
D. all of the above
Answer : D

22. To which region does pain, from the left mid ureter, refer to?
A. the loin region
B. the inguinal region
C. the umbilical region
D. the penis or clitors
Answer : B

23. What is false concerning PSA molecule?
A. the free form of PSA exists in small proportions in the body, and found mainly in BPH and in the ejaculate
B. ?1- anti chymotrypsin binds to 3 epitopes of the PSA molecule to form a complexed PSA
C. ?2- macroglobulin binds to 5 epitopes of the PSA molecule to form a complexed PSA
D. the purified PSA molecule has a molecular weight of 90 kDa
Answer : D

24. What is the most likely cause of large scrotal hematoma in neonates?
A. clotting factor VIII deficiency
B. clotting factor IX deficiency
C. breech delivery
D. scrotal cavernous haemangioma
Answer : C

25. What do the specialized cells, at the juxtaglomerular apparatus, produce?
A. erythropoietin
B. renin
C. angiotensin I
D. angiotensinogen
Answer : B

26. Which of the following explains infertility in liver cirrhosis male patients?
A. decrease plasma estradiol levels
B. increase plasma testosterone-estradiol-binding globulin levels
C. suppression of suprarenal androgens
D. exaggerated pituitary response to feedback hormones
Answer : B

27. Which of the prostate medications could result in significant hypotension?
A. finasteride
B. prazosin
C. silodosin
D. vardenafil
Answer : B

28. Bacterial resistance to antibiotics may occur because of:
A. inherited chromosomal-mediated resistance
B. acquired chromosomal-mediated resistance
C. extrachromosomal-mediated resistance
D. all of the above
Answer : D

29. Which of the prostate medications could result in retrograde ejaculation?
A. tamsulosin
B. doxazosin
C. dutasteride
D. alfuzosin
Answer : A

30. Which nephron segment contains the most diluted urine in central diabetes insipidus patient?
A. proximal convoluted tubules
B. distal convoluted tubules
C. collecting duct
D. loop of Henle
Answer : C

31. At which week of gestation do the primordial germ cells migrate to form the genital ridges?
A. third
B. fourth
C. fifth
D. seventh
Answer : C

32. What is false concerning fosfomycin antibiotic?
A. has a limited cross-resistance with most common antibacterial agents
B. causes injection site reactions
C. is active against most uropathogens
D. is effective as a single-dose agent
Answer : B

33. How does estrogen prevent lower UTI in postmenopausal women?
A. increasing vaginal secretions
B. decreasing vaginal pH
C. increasing normal vaginal flora
D. decreasing bacterial adherence
Answer : B

34. What do urine tests examine to detect hematuria?
A. catalase activity of erythrocytes
B. peroxidase activity of erythrocytes
C. lyase activity of erythrocytes
D. none of the above
Answer : B

35. Which artery(ies) supply(ies) the prostate?
A. middle rectal
B. inferior vesical
C. a & b
D. none of the above
Answer : C

36. Which agent is safe to kidneys?
A. amoxicillin
B. gentamycin
C. diclofenac
D. herb extract
Answer : A

37. What causes Cushing`s disease is:
A. bilateral adrenal hyperplasia
B. pituitary over secretion of ACTH
C. exogenous administration of glucocorticoids
D. immune-mediated disease
Answer : B

38. Which of the following is NOT a component of the normal semen?
A. zinc
B. fructose
C. prostate-specific antigen
D. alkaline phosphatase
Answer : D

39. Which of the following mediates calcium reabsorption in the distal renal tubules?
A. aldosterone
B. hypocalcemia
C. parathyroid hormone
D. vitamin D
Answer : C

40. What causes ureteral dilation during pregnancy is:
A. mechanical compression by the gravid uterus
B. physiological increase urine flow during pregnancy
C. elevated levels of progesterone
D. reflex inhibition of ureteral contractions
Answer : A

41. Renal blood flow is autoregulated by:
A. sympathetic nervous system
B. parasympathetic nervous system
C. urinary output
D. afferent arteriolar resistance
Answer : D

42. What is the approximated bladder capacity of an 8 yrs. girl?
A. 150 ml
B. 200 ml
C. 250 ml
D. 300 ml
Answer : D

43. Which of the following is false regarding zona glomeruloza?
A. the most superficial layer of the adrenal cortex
B. responses to increased potassium levels, renin or decreased renal blood flow
C. it causes pheochromocytoma
D. secretes aldosterone
Answer : C

44. What is the creatinine clearance in ml/min for a 70 kg man aging 50 yrs. with 1.1 mg/dL serum creatinine?
A. 79.54
B. 44.19
C. 84.15
D. 94.25
Answer : A

45. Which microbe causes red diaper syndrome?
A. Serratia marcescens
B. Streptococcus pyogenes
C. Clostridium difficile
D. Staphylococcus saprophyticus
Answer : A

46. Which statement is true about the female urethra?
A. harder to catheterize when compared to the male urethra
B. 4 inch long
C. opens into the vestibule below the clitoris
D. gets wider at the post-menopausal age
Answer : C

47. Which statement is false concerning microhematuria?
A. malignancy is identified in patients presenting with microhematuria more than in patients presenting with gross hematuria
B. microscopic hematuria is defined as > 3 red blood cells per high powered field (RBC/hpf) on a single specimen
C. warrants full hematuria workup
D. history of cigarette smoking is of significance
Answer : A

48. Which disease is described best by the following manifestations: grand mal epilepsy, mental retardation, hypertension, angiomyolipoma, adenoma sebaceum, bilateral enlarged kidneys, and normal renal function?
A. autosomal dominant polycystic kidney disease
B. von Hippel-Lindau disease
C. tuberous sclerosis
D. Sturge-Webber syndrome
Answer : C

49. Which statement is false concerning capacitation of spermatozoa?
A. occurs after acrosome reaction
B. entails removal of a glycoprotein layer
C. it is a biochemical event of sperm maturation
D. changes occur in the female genital tract
Answer : A

50. Which of the following might cause sterile pyuria?
A. renal tuberculosis
B. urinary tract stones
C. interstitial cystitis
D. all of the above
Answer : D