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Tumors of the prostate MCQ Question with Answer

Tumors of the prostate MCQ with detailed explanation for interview, entrance and competitive exams. Explanation are given for understanding.

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Question No : 1
What is false concerning Gleason scoring system for prostate cancers?

ranges from 0 -10 based on a histologic evaluation of tumor specimens
based on the 2 most common histologic patterns
greatly relies on the skills and experience of the pathologist
a score of 7 indicates a moderate-grade or moderately differentiated tumor
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Question No : 2
What is false concerning the interpretation of Gleason scoring system?

a low score means the cancer tissue is similar to normal prostate tissue
it indicates how likely the tumor will spread
the more cellular atypia observed the higher scoring will be
it relies only on the glandular architectural pattern
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Question No : 3
In descending order, to where do prostate cancers metastasize?

lymph nodes, bone, lung, bladder, liver, and adrenal glands
bone, lung, lymph nodes, liver, bladder, and adrenal glands
lung, liver, lymph nodes, bone, adrenal glands, and bladder
liver, lung, bone, lymph nodes, bladder, and adrenal glands
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Question No : 4
Following bilateral orchiectomy for prostate cancer, testosterone will:

initially drop to nadir, and then recover over 2 weeks
decline by 50% within 2 weeks and then normalize
decline by 90% within 24 hours
decline by 70%
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Question No : 5
Which PSA value interpretation is incorrect?

> 50% of men with PSA > 10 ng/mL have the disease beyond the prostate
pelvic lymph node involvement is found in PSA > 20 ng/mL
70% of men with a PSA between 4 and 10 ng/mL have organ-confined disease
80% of men with PSA < 4 ng/mL have organ-confined disease
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Question No : 6
What is the likelihood that patients with positive surgical margins after radical prostatectomy will be cured for prostate cancer?

never
unlikely
likely
always
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Question No : 7
What is the primary mechanism of prostate tissue ablation using high-intensity focused ultrasound?

disruption of protein synthesis
coagulative necrosis
cell wall destruction
DNA damage
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