Urologic infections and inflammations 1000+ MCQ with answer for UPSC CDS

1. Epididymal cysts are common in the following conditions,
EXCEPT:
A. von Hippel-Lindau disease
B. tuberous sclerosis
C. cystic fibrosis
D. autosomal dominant polycystic kidney disease
Answer : B

2. Management of acute epididymo-orchitis in hospitalized patients includes all of the following, EXCEPT:
A. scrotal support and elevation
B. ice packs
C. non-steroidal anti-inflammatory agents
D. urethral catheterization
Answer : D

3. What is the ideal antibiotic class for self-start therapy on treating recurrent cystitis in a 32 yrs. married woman?
A. aminopenicillins
B. fluoroquinolones
C. aminoglycosides
D. nitrofurantoins
Answer : B

4. HIV infection increases the incidence of the following cancers, EXCEPT:
A. Kaposi sarcoma,
B. Hodgkin lymphoma
C. non-Hodgkin lymphoma
D. cervical cancer
Answer : B

5. Which statement best defines reinfection?
A. a new episode of UTI caused by different species or occurring at long intervals
B. recurrent UTIs caused by the same organism in each instance, classically, at close intervals
C. recurrent UTIs due to failure of medical therapy to eradicate the infection
D. recurrent UTIs due to a persistent pathology that is obstinate to surgery
Answer : A

6. What is true regarding nephrogenic adenoma of the bladder?
A. results from ectopic nephrogenic blastema cells in the detrusor muscle
B. might undergo malignant transformation in 15 40% of the cases
C. on cystoscopy, it appears as a bladder mucosal irregularity or large intramural mass
D. the preferred treatment is cystectomy and urinary diversion
Answer : C

7. What type of human Herpes virus is implicated in all forms of Kaposi sarcoma?
A. 2
B. 6
C. 7
D. 8
Answer : D

8. What is essential on diagnosing bladder pain syndrome BPS/IC?
A. sterile pyuria on 3 consecutive cultures
B. the presence of glomerulations and/or Hunner`s ulcer on endoscopy
C. pain and discomfort related to the bladder
D. urgency and frequency with no documented infection
Answer : C

9. What is true regarding contrast CT imaging for a renal abscess?
A. abscess appears as a low attenuation cystic cavity containing gas
B. renal parenchyma around the abscess cavity may show hypo enhancement in nephrogram phase
C. associated fascial and septal thickening are seen with obliteration of perinephric fat
D. all of the above
Answer : D

10. What is false concerning foreign body cystitis?
A. most commonly due to indwelling catheters
B. the areas of inflammation are usually confined to the lateral walls or the dome of the bladder
C. radiographic changes are nonspecific or present as bullous edema
D. indwelling catheters are associated with squamous cell carcinoma of the bladder
Answer : B

11. What is true regarding urinary catheter-associated UTI (CAUTI)?
A. indwelling catheter insertion must be under sterile condition
B. systemic antibiotics help best in preventing bacteriuria
C. greater than 90% of nosocomial UTIs are related to urethral catheters
D. Intermittent catheterization carries the incidence of 1-3% of developing bacteriuria per insertion
Answer : D

12. What are the target immune cells for HIV?
A. phagocytes
B. CD4 T cells
C. B lymphocytes
D. natural killer cells
Answer : B

13. What is false concerning radiation cystitis?
A. the average time from the beginning of radiation therapy to initial symptoms could be 2 4 weeks
B. treatment with stationary radiation, portals carry a higher risk of morbidity than treatment with rotating portals do
C. it occurs in about 10% of patients treated with definitive irradiation therapy for prostate cancer after 10 years
D. most cases are mildly affected and require no specific therapy
Answer : A

14. What type of cells is implicated most in the pathogenesis of BPS/IC?
A. histocytes
B. T lymphocytes
C. mast cells
D. B lymphocytes
Answer : C

15. What is true concerning HIV infection?
A. HIV is a retrovirus that infects B-cells and dendritic cells
B. circumcised men are at lower risk for HIV infection
C. HPV infection increases the risk for cancers in HIV patients by 6.3 times
D. plasma HIV RNA load is a predictor of disease remission
Answer : B

16. Under which surgical wound classification, does diagnostic cystoscopy under sterile technique fit?
A. dirty - infected
B. contaminated
C. clean - contaminated
D. clean
Answer : C

17. What are the sequelae of recurrent uncomplicated UTI in young women?
A. minimal
B. chronic persistent infections
C. chronic relapsing infections
D. bouts of chronic pyelonephritis
Answer : A

18. What is true regarding acute pyelonephritis?
A. a cause of obstruction should be sought
B. PCN is placed to decompress the kidney and preserve renal function
C. blood-born staphylococci are commoner than ascending E.coli infections
D. blood and urine cultures mut dictate the antibiotic choice from day 1
Answer : A

19. What is false regarding Gonorrheal STD in women?
A. nucleic acid amplification tests are the preferred to diagnose Gonococcal and Chlamydial infections
B. shows dark yellow, purulent, thick urethral discharge
C. the most common site of the infection is the endocervix
D. the incubation period is 2 3 weeks
Answer : D

20. What is false regarding schistosomal cystitis?
A. an esinophilic immune reaction is generated in response to the eggs
B. chronic schistosomiasis can eventually result in small bladder and the development of cancers
C. schistosoma mansoni often causes urinary tract infections
D. could cause inflammatory polys and recurrent hematuria
Answer : C

21. A 40 yrs. man presents with clinical acute pyelonephritis, on intravenous antibiotics for 4 days, CT shows a renal abscess. What is next in the treatment?
A. carry on the full antibiotic course, and then repeat CT
B. incision and drainage of the renal abscess with/without nephrectomy
C. the abscess size dictates management
D. perc. drainage of the renal abscess
Answer : C

22. Using low-dose prophylactic or suppressive antimicrobials might be an option in treating the following type of prostatitis:
A. acute bacterial prostatitis presenting with abscess formation
B. recurrent or refractory chronic bacterial prostatitis
C. asymptomatic prostatitis with pyuria resistant to common antimicrobials
D. curiously, chronic inflammatory prostatitis could respond to low-dose suppressive antibiotic
Answer : B

23. What are the most indicative symptoms of chronic pyelonephritis?
A. fever and chills
B. suprapubic pain and pyuria
C. flank pain and tenderness
D. none of the above
Answer : D

24. What condition is associated with renal papillary necrosis?
A. nephrotic syndrome
B. hypertension
C. sickle cell hemoglobinopathy
D. sarcoidosis
Answer : C

25. What is false concerning the cystoscopic findings of interstitial cystitis?
A. Hunner`s ulcers are multiple ulcerative patches surrounded by mucosal congestion on the dome or lateral walls
B. ulcers might get distorted after overdistention, because discrete areas of mucosal scarring rupture during the procedure
C. in non-ulcerative type, overdistention demonstrates glomerulations on the dome and lateral walls
D. overdistention results in mucosal tears and submucosal hemorrhage
Answer : B

26. What is false concerning Xanthogranulomatous Pyelonephritis?
A. is most commonly associated with Proteus or E. coli infection
B. is characterized by lipid-laden foamy macrophages
C. the overall prognosis is poor
D. it might involve adjacent structures or organs
Answer : C

27. What is the commonest cause of relapsing UTI in males?
A. chronic epididymitis
B. epididymo-orchitis
C. chronic bacterial prostatitis
D. venereal cysto-urethritis
Answer : C

28. The virulence of uropathogenic E.coli depends on all the following,
EXCEPT:
A. P blood-group antigen
B. P fimbriae in descending infections
C. emolysins
D. Dr family of adhesins in ascending infections
Answer : B

29. What is false regarding pediatric renal parenchyma scarring?
A. chronic pyelonephritis and HTN lead to ESRD in 10% of the cases
B. neonatal symptoms of UTI are vague and non-specific, that delay the diagnosis and end in more scarring
C. despite adequate treatment, scarring continues after an attack of pyelonephritis as a chronic immune reaction against renal tubules
D. neonates have low intrarenal pelvic pressure, that predisposes to ascending infections
Answer : D

30. What is true concerning the treatment of catheter associated bacteriuria?
A. should be flushed frequently, but no antibiotic is advised
B. should be treated if febrile UTI has developed
C. should be treated only if urine culture is positive
D. should be treated once the catheter is removed
Answer : B

31. What kind of non-infectious cystitis, do patients with systemic lupus erythematosus (SLE), likely to develop?
A. cystitis glandularis
B. cystitis cystica
C. esinophilic cystitis
D. cystitis follicularis
Answer : C

32. What is NOT a complication of mumps orchitis?
A. infertility
B. hypogonadotropic hypogonadism
C. non seminomatous germ cell tumor
D. chronic orchalgia
Answer : C

33. What is the laboratory differentiation between type III-a and type III-b prostatitis?
A. the cytological examination of the urine and/or EPS
B. transrectal ultrasonographic examination
C. the presence of ?10 WBCs/HPF in the urine with negative culture in type III-b
D. the positive urine culture, and negative EPS support type III-a
Answer : A

34. In which segmented voided bladder (VB) specimen, the diagnosis of chronic prostatitis is confirmed?
A. VB1 and VB3
B. prostatic secretions and the VB3
C. prostatic secretions and the VB2
D. prostatic secretions and the VB1
Answer : B

35. Histologically, the pathognomonic finding of Fournier gangrene include:
A. necrosis of the superficial and deep fascial planes
B. fibrinoid thrombosis of the nutrient arterioles
C. polymorphonuclear cell infiltration
D. all of the above
Answer : D

37. Patients with bladder pain syndrome have:
A. a history of repeated urologic and/or gynecologic procedures
B. 10 fold higher incidence of childhood voiding problems
C. 4 fold higher incidence of anxiety-depression syndrome
D. 6 fold higher incidence of psychosomatic disorders
Answer : B

38. What is false regarding the etiology and treatment of orchialgia syndrome?
A. small indirect inguinal hernia may irritate the genital branch of genitofemoral nerve causing orchialgia
B. might respond to a selective nerve block
C. the recommended treatment is orchiectomy with implantation of a testicular prosthesis
D. psychotherapy and stress management might alleviate the pain
Answer : C

39. Which of the following conditions is NOT associated with interstitial cystitis?
A. inflammatory bowel disease
B. rheumatoid arthritis
C. systemic lupus erythematosus
D. fibromyalgia
Answer : B

40. Which of the following is NOT a first-choice antimicrobial agent for uncomplicated acute cystitis in women?
A. nitrofurantoin monohydrate/macrocrystals
B. trimethoprim-sulfamethoxazole
C. ampicillin
D. fosfomycin
Answer : C

41. Which treatment modality has NO proven efficacy in CP/CPPS?
A. selective nerve block
B. balloon dilation
C. botulinum A toxin injection
D. ESWL
Answer : B

42. Which of the following does NOT cause unresolved bacteriuria?
A. giant staghorn stone
B. perivesical abscess with fistula to the bladder
C. bacterial resistance
D. self-inflicted infection
Answer : B

43. What is the most important pharmacokinetic property of a drug to cure UTI?
A. mode of administration
B. level in the serum
C. level in the urine
D. dosage
Answer : C

44. What host`s factors do NOT increase the risk of developing infections?
A. advanced age
B. anatomical anomalies
C. poor drug compliance
D. smoking
Answer : C

45. When comparing nosocomial to community-acquired UTI, the latter is:
A. 45% are caused by E. coli
B. related to an indwelling urinary catheter in approximately 40% of cases
C. responds fairly to oral antibiotics
D. tends to report higher antibiotic resistance
Answer : C

46. What is true regarding balanoposthitis?
A. is best diagnosed by ascending urethrography
B. occurs mostly in diabetic and immunosuppressed patients
C. could be due to maceration injury, irritant dermatitis, or Candida
D. commonly presents with deep inguinal lymphadenopathy
Answer : C

47. What is false regarding Fournier`s gangrene?
A. is defined as a polymicrobial chronic infection of the perineal, perianal, or genital areas
B. as the disease progresses, branches from the inferior epigastric, deep circumflex iliac, and external pudendal arteries get thrombosed
C. presents as a dark skinned-scrotum, subcutaneous crepitation, and foul smell
D. surgical debridement often spares the testes
Answer : A

48. A 48 yrs. woman presents with recurrent cystitis. Cystoscopy showed a raised bladder lesion. Biopsies from the lesion reveals Von Hansemann histiocytes, and Michaelis-Gutmann bodies. What is the treatment?
A. sulfonamide for several months
B. TUR of the bladder lesion followed by proper staging
C. radical cystectomy and urinary diversion
D. intravesical installation of mitomycin without irradiation
Answer : A

49. What virus(s) could cause orchitis?
A. Coxsackie B
B. Epstein-Barr
C. varicella
D. all of the above
Answer : D

50. Screening for bacteriuria is mostly indicated for:
A. seniors house residents
B. ICU patients with indwelling urinary catheters
C. pregnant women
D. neurogenic bladder patients on CIC
Answer : C