Urology Basic Science MCQ Solved Paper for IIFT

1. Which anomaly might accompany horseshoe kidneys?
A. ureteropelvic junction obstruction
B. ureterocele
C. ureteral reflux
D. ureteral atresia
Answer : A

2. Which agent is safe to kidneys?
A. amoxicillin
B. gentamycin
C. diclofenac
D. herb extract
Answer : A

3. Which of the following is NOT a cause of hypocitraturia?
A. high protein diet
B. hypokalaemia
C. proximal renal tubular acidosis
D. idiopathic
Answer : C

4. When should a 70 yrs. man with 40 ml prostate volume, and total PSA of 2.0 ng/ml, go for a prostate biopsy?
A. if PSA reading had exceeded 2.7 ng/ml over 12 months
B. if free PSA reading was less than 0.4 ng/ml
C. if total PSA reading was greater than 8 ng/ml
D. any of the above
Answer : D

5. Which of the following process(es) is (are) reversible?
A. 5?-reductase enzyme reduces testosterone to DHT
B. aromatase enzyme reduces testosterone to estrogen
C. PSA molecule binds to ?1-antichymotrypsin and ?2-macroglobulin
D. none of the above
Answer : D

6. Bacterial resistance to antibiotics may occur because of:
A. inherited chromosomal-mediated resistance
B. acquired chromosomal-mediated resistance
C. extrachromosomal-mediated resistance
D. all of the above
Answer : D

7. Which class of the following diuretics could cause erectile dysfunction?
A. loop diuretics
B. thiazide diuretics
C. potassium sparing diuretics
D. osmotic diuretics
Answer : B

8. At what month of intra-uterine life do testes descend into the scrotum with the aid of the intra-abdominal pressure and the gubernacula?
A. sixth
B. seventh
C. eighth
D. ninth
Answer : B

9. What class of antibiotics might cause vestibular and/or auditory impairment?
A. aminoglycosides
B. ?antipseudomonal penicillins
C. cephalosporins
D. fluoroquinolones
Answer : A

10. The majority of circulating testosterone is:
A. bound to sex hormone-binding globulin
B. free
C. bound to ?1-antichymotrypsin
D. bound to albumin
Answer : A

11. What is the most likely diagnosis of an erectile dysfunction patient with low plasma testosterone and high prolactin levels?
A. pituitary adenoma
B. adrenal adenoma
C. Kallmann syndrome
D. Klinefelter syndrome
Answer : A

12. What is the nature of the prostate-specific antigen?
A. protease
B. lyase
C. carboxylase
D. hydrolase
Answer : A

13. Which lab results indicate poor prognosis of male infertility?
A. azoospermia; normal FSH; increase LH
B. azoospermia; decrease FSH; normal LH
C. oligospermia; increase FSH; normal LH
D. oligospermia; normal FSH; decrease LH
Answer : C

14. Which type of urinary casts are solidified TammHorsfall mucoproteins secreted from the tubular epithelial cells of individual nephrons?
A. granular
B. hyaline
C. waxy
D. pigment
Answer : B

15. What are the first and second most common zones from where prostate cancers arise?
A. central then transitional
B. peripheral then transitional
C. peripheral then central
D. transitional then central
Answer : B

16. Which of the following contributes second to the seminal fluid by volume?
A. seminal vesicles
B. the prostate
C. testes
D. bulbourethral glands
Answer : B

17. What is the most significant innervation of the vas deferens?
A. sympathetic nervous system
B. parasympathetic nervous system
C. somatic nervous system
D. none of the above
Answer : A

18. Which statement is true about the female urethra?
A. harder to catheterize when compared to the male urethra
B. 4 inch long
C. opens into the vestibule below the clitoris
D. gets wider at the post-menopausal age
Answer : C

19. What is the creatinine clearance in ml/min for a 70 kg man aging 50 yrs. with 1.1 mg/dL serum creatinine?
A. 79.54
B. 44.19
C. 84.15
D. 94.25
Answer : A

20. Which antibiotic is the best to treat soft tissue infection with methicillin-resistant Staphylococcus aureus (MRSA) in hospitalized patients?
A. vancomycin
B. cefotaxime
C. penicillin G
D. tobramycin
Answer : A

21. What does apoptosis mean?
A. programmed cell death
B. new vascular formation
C. uninhibited neural stimulation
D. premature muscular contraction
Answer : A

22. What nerve provides the major neural supply to the striated urinary sphincter and levator ani muscle?
A. somatic innervations B. sympathetic fibers from T11 - L2
C. the pudendal nerve
D. the obturator nerve
Answer : C

23. Which hormone measures testicular germ cell function best?
A. LH
B. FSH
C. HCG
D. none of the above
Answer : B

24. Which of the following is false regarding zona glomeruloza?
A. the most superficial layer of the adrenal cortex
B. responses to increased potassium levels, renin or decreased renal blood flow
C. it causes pheochromocytoma
D. secretes aldosterone
Answer : C

25. Which microbe causes red diaper syndrome?
A. Serratia marcescens
B. Streptococcus pyogenes
C. Clostridium difficile
D. Staphylococcus saprophyticus
Answer : A

26. Which ?- adrenergic receptor subtype mediates smooth muscle contraction of the prostate?
A. ?1-A
B. ?2-A
C. ?1-B
D. ?2-B
Answer : A

27. Which medicine(s) might enhance hypoprothrombinemic effect on oral anticoagulants?
A. allopurinol
B. aminoglycosides
C. cimetidine
D. all of the above
Answer : D

28. What is the best method to evaluate calcium levels in the urine?
A. from early morning urine sample
B. comparing urine and serum calcium at a given time
C. performing 24 urine collection
D. from a mid-stream urine sample
Answer : C

29. What does make UTI more common in mid-aged females than in males?
A. short female urethra
B. pregnancy
C. vaginal colonization with enterobacteria
D. all the above
Answer : D

30. The epithelial component of the prostate consists of all of the following, EXCEPT:
A. basal cells
B. intermediate cells
C. tubulo-columnar cells
D. neuroendocrine cells
Answer : C

31. What is the most likely cause of large scrotal hematoma in neonates?
A. clotting factor VIII deficiency
B. clotting factor IX deficiency
C. breech delivery
D. scrotal cavernous haemangioma
Answer : C

32. The manifestations of autonomic dysreflexia include:
A. hypotension and tachycardia
B. hypotension and bradycardia
C. hypertension and tachycardia
D. hypertension and bradycardia
Answer : D

33. Which of the following is NOT a component of the normal semen?
A. zinc
B. fructose
C. prostate-specific antigen
D. alkaline phosphatase
Answer : D

34. Where do Cowper`s gland ducts drain into?
A. ejaculatory ducts
B. prostatic urethra
C. membranous urethra
D. bulbous urethra
Answer : D

35. Which statement is false concerning capacitation of spermatozoa?
A. occurs after acrosome reaction
B. entails removal of a glycoprotein layer
C. it is a biochemical event of sperm maturation
D. changes occur in the female genital tract
Answer : A

36. Which action of thigh muscles could be impaired if the obturator nerve was injured during endoscopic resection of bladder tumors?
A. adduction
B. abduction
C. flexion
D. extension
Answer : A

37. What is the most significant complication of cyclosporine?
A. hepatic toxicity
B. renal toxicity
C. neural toxicity
D. cardiac toxicity
Answer : B

38. How long post bilateral orchiectomy, will patients be functionally castrated?
A. immediately
B. after 2 hrs.
C. after 12 hrs.
D. after 24 hrs.
Answer : B

39. What is the function of PSA in semen?
A. increases semen volume
B. has antimicrobial activity
C. liquefies the seminal coagulum
D. decreases semen pH
Answer : C

40. What causes pure testicular feminization is:
A. over estrogen synthesis
B. defective end-organ androgen response
C. extra X chromosome (XXY)
D. failure of genital ridge regression
Answer : B

41. How many renal papillae are there in a typical kidney?
A. 4 to 6
B. 7 to 9
C. 10 to 12
D. 13 to 14
Answer : B

42. What is the most common cause of hematuria in men over 60 yrs.?
A. kidney stones
B. glomerulonephritis
C. BPH
D. bladder cancer
Answer : C

43. Branches of what artery travel under the endopelvic fascia form the prostate to the sidewall of the pelvis?
A. obturator artery
B. midrectal artery
C. inferior vesical artery
D. pudendal artery
Answer : D

44. What is the appropriate intravenous maintenance fluid for a 16 kg girl?
A. 43 ml/hr of normal saline
B. 78 ml/hr of ¼ normal saline
C. 69 ml/hr of ½ normal saline
D. 54 ml/hr of ¼ normal saline
Answer : D

45. What causes pink diaper syndrome is (are): A. Staphylococcus epidermidis in the urine
B. dried urate crystals on the diaper
C. Adenovirus 11 in the urine
D. Candidiasis in the urine
Answer : B

46. Which statement is NOT related to Klinefelter syndrome?
A. sterility is the rule
B. has a considerable short life span
C. treatment requires testicular microdissection and sperm extraction
D. 47 XXY karyotype
Answer : B

47. What is the earliest clinical sign of puberty in boys?
A. hoarseness of voice
B. enlargement of testes
C. appearance of axillary hair
D. change in body odor
Answer : B

48. Which of the following explains infertility in liver cirrhosis male patients?
A. decrease plasma estradiol levels
B. increase plasma testosterone-estradiol-binding globulin levels
C. suppression of suprarenal androgens
D. exaggerated pituitary response to feedback hormones
Answer : B

49. From where does the main parasympathetic efferent innervation to the pelvic plexus arise?
A. S1
B. S2-S4
C. T11-L2
D. L3-S1
Answer : B

50. All of the following develop from the mesonephric ducts, EXCEPT:
A. vas deferens
B. seminal vesicles
C. appendix epididymis
D. appendix testis
Answer : D