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4

What is false concerning testicular germ cell tumors (GCT)?

A. in a patient with a history of GCTs, the finding of testicular microlithiasis on ultrasonography poses a higher risk of intratubular germ cell neoplasia

B. occur bilaterally approximately 2% of cases

C. are extragonadal in 1 - 5%

D. are more likely to contain embryonal tumor cells than tumors arising in the testis

Correct Answer :

D. are more likely to contain embryonal tumor cells than tumors arising in the testis


are more likely to contain yolk sac tumor elements than tumors arising in the testis.

Related Questions

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Testicular cancer patients with bulky retroperitoneal lymph node disease greater than 3 cm should:

A. undergo laparoscopic lymph node sampling

B. receive induction chemotherapy

C. undergo extensive retroperitoneal lymph node dissection

D. go for palliative therapy

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4

What is the most common presentation of testicular cancers?

A. unilateral hydrocele

B. dull ache or heavy sensation in the lower abdomen

C. painless swelling or a nodule in the testicle

D. incidental finding on scrotal ultrasonography

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4

Which of the following is NOT a risk factor for developing testicular cancers?

A. environmental conditions exposing the testes to high temperature

B. 47XXY genotype

C. prior testicular cancers

D. cryptorchidism

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4

What is false concerning testicular germ cell tumors (GCT)?

A. in a patient with a history of GCTs, the finding of testicular microlithiasis on ultrasonography poses a higher risk of intratubular germ cell neoplasia

B. occur bilaterally approximately 2% of cases

C. are extragonadal in 1 - 5%

D. are more likely to contain embryonal tumor cells than tumors arising in the testis

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4

On managing testicular tumors, testis-sparing surgery is NOT indicated in:

A. suspected germ cell tumor (GCT) with a normal contralateral testis

B. in case of bilateral synchronous testicular GCT

C. suspected benign testicular lesions

D. suspected GCT of < 2 cm tumor size in a solitary testis

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4

After chemotherapy for testicular cancers, how long does it take for spermatogenesis to return to the norm?

A. 3 months

B. 3 spermatogenic cycles

C. 3 yrs.

D. damage is permanent

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4

On presentation, what is the percentage of infertility among testicular germ cell tumor patients?

A. 10 - 20%

B. 20 - 60%

C. 60 - 80%

D. 80 - 90%

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4

What is false concerning surgical care for testicular cancer patients?

A. patients in whom retroperitoneal LN dissection (RPLND) reveals viable cancer cells after chemotherapy, subsequent chemotherapy is recommended

B. surgical resection is recommended for patients with residual disease after chemotherapy

C. open nerve-sparing RPLND might lead to premature ejaculation

D. in non-seminoma patients stage I-A, I-B, 1S on long-term surveillance, relapses are expected in 80% of cases within the first year after orchiectomy

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4

What is true regarding biological markers of testicular cancers?

A. high levels of α-FP are found only in non-seminomas

B. high levels of α-FP may result from marijuana use

C. β-hCG levels above 10,000 mIU/mL are seen only in germ cell tumors and hepatocellular carcinoma

D. LDH is a useful marker for surveillance after tumor extirpation

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4

Seminomas are classified as good risk when which of the following is (are) present:

A. stem from the periphery of the testis

B. no non-pulmonary visceral metastases

C. normal α-FP, β-hCG, and LDH markers

D. all of the above

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4

Late toxicity of chemotherapy for testicular cancers might result in all of the following, EXCEPT:

A. peripheral neuropathy

B. renal failure

C. Raynaud phenomenon

D. hypogonadism

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4

What is the 5-yr survival rate for a localized testicular cancer?

A. over 80%

B. over 85%

C. over 90 %

D. over 95 %

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4

What is the most common para-testicular tumor in children?

A. rhabdomyosarcoma

B. liposarcoma

C. sarcomatoid tumor

D. angiosarcoma

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4

What is the most common para-testicular tumor in adults?

A. rhabdomyosarcoma

B. liposarcoma

C. sarcomatoid tumor

D. angiosarcoma

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4

What is the commonest site of cancer occurrence in the male urethra?

A. fossa navicularis

B. bulbomembranous urethra

C. prostatic urethra

D. external urethral meatus

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4

6.What is false regarding testicular cancer and cryptorchidism?

A. the risk of developing germ cell tumor when an undescended testis is in the abdomen is greater than when it is in the inguinal canal

B. orchiopexy for boys younger than 6 yrs. lowers the risk of cancer development

C. a normally descended testis carries 5-20% risk of developing cancer when its mate is undescended

D. the risk of cancer increases in cryptorchid patients over 33 yrs. of age

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4

What is the role of positron emission tomography (PET) in testicular cancer patients?

A. evaluates post chemotherapy residual masses in pure seminoma cases

B. helps stage non-seminomatous germ cell tumors

C. all of the above

D. used for active surveillance in non-operable cases

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4

What is true regarding retroperitoneal lymph nodes involvement in testicular cancers?

A. left testicular tumors spread to the periaortic lymph nodes

B. right testicular tumors spread to the interaortocaval lymph nodes

C. the fashion of further spread in the retroperitoneum is from right to left

D. all of the above

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4

What is the percentage of germ cell tumors among all testicular cancers?

A. greater than 90%

B. lesser than 40%

C. greater than 70%

D. lesser than 20%

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4

What is true regarding radical inguinal orchiectomy for testicular cancer?

A. is considered based on a histologic evidence

B. should not be performed through a scrotal incision

C. preoperative biopsy is required for histologic examination

D. entails early clamping of the cord at the external inguinal ring level

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4

What is false concerning testicular tumor markers?

A. elevation of only α-FP indicates pure non-seminoma

B. elevation of α-FP might occur in chronic liver disease, hepatitis, and alcohol abuse

C. elevation of LDH indicates tumor burden and growth rate

D. elevation of β-hCG above 10,000 mIU/mL is seen only in germ cell tumors

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4

What is false concerning tumor markers of seminoma?

A. in pure seminoma α-FP is normal

B. if syncytiotrophoblastic giant cells are present, β-hCG may be elevated

C. spermatocytic seminomas rarely metastasize without sarcomatous differentiation

D. pure seminoma constitutes approximately 90% of pure germ cell tumors

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4

In testicular cancer patients with residual disease after chemotherapy, what type is found in approximately 45% of resected specimens?

A. polyembryoma

B. teratoma

C. embryonal carcinoma

D. mixed germ cell tumor

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4

Which of the following statements is false concerning testicular tumor markers?

A. α-FP and/or β-hCG are elevated in approximately 80% to 85% of patients with non-seminomatous germ cell tumors

B. β-hCG increases in either seminoma or non-seminoma

C. LDH increases in 30% to 80% of pure seminoma patients and in 60% of non-seminoma patients

D. high levels of α-FP might induce nipple tenderness or gynecomastia

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4

Testicular germ cell tumors that produce only α-FP are:

A. yolk cell tumors

B. choriocarcinomas

C. embryonal carcinomas

D. pure seminomas

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4

Seminoma is rare in patients:

A. younger than 10 yrs.

B. older than 50 yrs.

C. between 20 27 yrs.

D. between 28 35 yrs.

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4

Leydig cell tumors and Sertoli cell tumors are benign in:

A. 60%

B. 70%

C. 80%

D. 90%

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4

What is the most common testicular neoplasm in men over 50?

A. lymphoma

B. spermatocytic seminoma

C. adenocarcinoma

D. cystadenoma

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4

What is the commonest testicular cancer in infants and young children?

A. choriocarcinoma

B. yolk cell tumor

C. embryonal carcinoma

D. seminoma

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4

What is false concerning intratubular germ cell neoplasia (ITGCN) of the testes?

A. adult choriocarcinoma arise from ITGCN

B. spermatocytic seminoma arises from ITGCN

C. typically, pediatric germ cell tumors (GCT) do not arise from ITGCN

D. ITGCN is the common precursor for most of adult male GCT