What is true concerning epithelial and stromal cells in BPH?
there is an increase in the number of epithelial and stromal cells
there is an increase in the size of epithelial and stromal cells
in BPH, epithelial to stromal cells ratio is 1:2
all of the above
Correct Answer :
A. there is an increase in the number of epithelial and stromal cells
the number, not the size of prostate cells that increases in BPH.
Related Questions
Complications related to obstructive BPH/LUTS include all of the following, EXCEPT:
bladder stones
prostate cancer
renal insufficiency
bladder diverticula
What is the likelihood that PSA level in men with acute urinary retention due to urethral stricture will decrease after catheterization?
never
unlikely
likely
always
Preferably, what is the last part of the prostate to be removed while performing TURP?
bladder neck
apex
median lobe
para-collecular
On treating BPH, which procedure provides the best tissue preservation for pathological examination?
TURP
TUIP
HoLEP
HoLRP
The most serious complication of TURP is:
damage to the internal sphincter
damage to the external sphincter
bladder perforation
damage to a ureteral orifice
What drug prevents recurrent gross hematuria secondary to BPH?
enoxaparin
silodosin
finasteride
tolterodine
What is true concerning epithelial and stromal cells in BPH?
there is an increase in the number of epithelial and stromal cells
there is an increase in the size of epithelial and stromal cells
in BPH, epithelial to stromal cells ratio is 1:2
all of the above
A 50% reduction of prostate size is expected after a 6-month therapy with:
alfuzosin
silodosin
finasteride
tamsulosin
Which statement is false regarding TURP syndrome?
occurs because of absorption of non-sodium-containing irrigating fluid
occurs only on using unipolar TURP
results in brain edema due to dilutional hyponatremia
positioning the patient in anti-Trendelenburg helps prevent the syndrome
c. each centimeter over the normal 2.5-cm prostate urethral length equates
an additional 15 g in prostate weight
each centimeter over the normal 1.5-cm prostate urethral length equates
an additional 5 g in prostate weight
. When comparing suprapubic to retropubic prostatectomy for removing prostatic adenoma, the former allows:
a. urethral stricture
bladder stones
BPH
prostatitis syndrome
. What is (are) the indication(s) of antimuscarinic agents and PDEIs
In BPH patients, follow up PSA is of value because:
it helps predict the response to 5α-reductase inhibitors
it monitors LUTS/BPH progression
BPH patients are at higher risk of developing prostate cancer
a & b
TURP carries an incidence of retrograde ejaculation of:
62 - 78%
48 - 61%
79 - 93%
34 - 47%
When comparing HoLEP to open prostatectomy for a 70 g prostatic adenoma removal; what parameter goes in favor of the latter?
operation time
duration of in-hospital stay
amount of blood transfused
time to catheter removal
What is false concerning needle ablation therapy of the prostate (TUNA)?
prostate sizes of up to 70 ml can be treated
not recommended in patients with metallic artificial hip
retreatment rates are lower than for TURP
can be performed in an office-based setting
What is (are) the favorite criterion (criteria) to prescribe 5α- reductase inhibitors for BPH cases?
PSA > 1.5 ng/dL
prostate volume > 40 ml
IPSS > 19
a & b
What is false regarding BPH genetics?
BPH is an inheritable and progressive disease
familial BPH presents at an older age when compared to sporadic cases
approximately 90% of men in their 80s have histologic evidence of BPH
BPH tends to be more severe and progressive in black men when compared to whites
A BPH patient presents with retention of urine. He is Catheterized. Later, he underwent TURP. When would the highest PSA value be?
before catheterization
after catheterization and before TURP
immediately after TURP
2 weeks after TURP
What is true regarding BPH and androgens?
as a man ages, the responsiveness of prostate cells to androgenic stimuli decreases
adrenal androgens have no role in BPH development
type-1 steroid 5 α-reductase is functionally active in the hair follicle
all of the above
Which statement(s) describe(s) the bladders response to an obstructing prostate?
it may develop detrusor instability with irritative LUTS
it may develop poor compliance with frequency and urgency symptoms
it may develop poor detrusor contractility with obstructive LUTS
all of the above
In BPH patients, total PSA level correlates to:
the glandular component of the prostate
the IPSS questionnaire points
the PVR
the transitional zone volume
A 55 yrs. male patient with familial BPH, IPSS 9, PSA 23ng/ml, prostate size 31 cc, PVR 54 cc, on watchful waiting management. Next step should be:
tamsulosin 0.8 mg
reassurance
repeat total and free PSA
diagnostic cystoscopy
What is false concerning bladder and prostate histology in BPH?
obstruction results in bladder smooth muscle hypertrophy and myofibroblasts deposition
BPH occurs chiefly in the transitional zone and periurethral tissues
BPH microscopical changes begin in early thirties
histologic findings of chronic prostatitis are common in BPH
In BPH, the etiology of acute urinary retention includes:
prostatic infarction
prostate infection
bladder overdistention
all of the above
Which of the following is NOT classified as a complicated LUTS?
LUTS with neurologic disease
LUTS with post-void dribble
LUTS with suspicious DRE
LUTS with hematuria
IPSS decreases after successful TURP because:
PSA decreases
the prostate size decreases
the complaints resolve
the Q.O.L improves
Transurethral incision of the prostate (TUIP):
is only indicated in small prostates
complications are related to the amount of lost blood and removed chips
is a minimal procedure where no risk of rectal injury or retrograde ejaculation have been reported
it entails making 1 or 2 incisions along all prostate lobes except the apical
What is (are) the indication(s) of upper urinary tract imaging in men with LUTS?
hematuria
recurrent urinary tract infection
renal insufficiency
all of the above
What is (are) true concerning IPSS questionnaire?
it focuses on last month`s symptoms
scores of moderate symptoms suggest surgical treatment if the patient`s quality of life was poor
it has been validated and translated to many languages
all of the above
On treating BPH, which procedure carries the risk of morcellator injury to the bladder?
PVP
HoLEP
HoLRP
TUMT