In BPH patients, which of the following measures reduces PSA value by one-half?
2 weeks after performing prostatic urethral lift
6-month treatment with 5α-reductase inhibitors
after placing a stent in the prostatic urethra
immediately after removing one-half of the prostate by TURP
Correct Answer :
B. 6-month treatment with 5α-reductase inhibitors
PSA is reduced by one-half in patients on 5α-reductase inhibitors.
Related Questions
In men with LUTS, which of the following is NOT a compelling indication for upper urinary tract imaging?
urolithiasis
receiving chemotherapy
upper tract surgery
painless hematuria
In an 80 yrs. diabetic man on insulin for 35 yrs.; what would be the proper sequence of developing the following obstructing BPH/LUTS?
frequency, over-flow incontinence, straining, retention
straining, frequency, over-flow incontinence, retention
straining, frequency, retention, over-flow incontinence
frequency, straining, retention, over-flow incontinence
Open prostatectomy is preferred in treating BPH with:
sizable bladder stones
Hutch diverticulum
a suspicion of cancer
a & b
Which statement is false regarding laser enucleation of the Prostate (HoLEP)?
provides tissue preservation for pathological examination
treats any size of prostatic adenoma
follows anatomic planes to remove the prostate in lobes
urinary incontinence is a significant drawback after HoLEP
In BPH patients, which of the following measures reduces PSA value by one-half?
2 weeks after performing prostatic urethral lift
6-month treatment with 5α-reductase inhibitors
after placing a stent in the prostatic urethra
immediately after removing one-half of the prostate by TURP
a. α-adrenergic blocker
combination of α-adrenergic blocker and 5α-reductase inhibitor
watchful waiting
TURP
. What is the commonest cause of LUTS in men beyond middle age?
a. lesser chance of post-operative urethral stricture
milder postoperative hematuria
tension-free bladder closure
extra-peritoneal approach
. When comparing TURP to open prostatectomy for removing prostatic adenoma, the latter has the following advantages, EXCEPT:
What is false concerning BPH and androgenic hormones?
the most potent androgenic hormones in BPH development is DHT
type-2 steroid 5 α-reductase, is most commonly found in the prostate
castrated individuals before puberty will not develop BPH
as a man ages, the number of androgen receptors in the prostate decreases
Which drug reduces the incidence of prostate cancer by 23% with a small increase in high-grade tumor incidence?
cetrorelix
flutamide
dutasteride
zanoterone
What is true regarding mirabegron, the β3 agonist, in treating BPH?
achieves better results when combined with antimuscarinic
enhances detrusor contractility resulting in higher Q-max
enhance detrusor relaxation during bladder-filling phase
increases voiding pressure that poses risk on renal function
What is false concerning needle ablation therapy of the prostate (TUNA)?
prostate sizes of up to 70 ml can be treated
not recommended in patients with metallic artificial hip
retreatment rates are lower than for TURP
can be performed in an office-based setting
a. operation cost
smaller incisions with a shorter hospital stay
lower risk for blood transfusion
none of the above
. What is the first-line management of uncomplicated LUTS due to large prostate?
The most serious drawback of anticholinergic drugs on BPH patients is:
renal insufficiency
urinary retention
dry mouth
painless hematuria
PSA value has a strong correlation with:
IPSS
post void residual
prostate volume
Q-max at uroflowmetry
a. no risk of dilutional hyponatremia
operating on patients with multiple bladder diverticula
operating on patients who cannot flex their hips and/or knees
unfavorable tissue preservation for pathological examination
. What is (are) the contraindication(s) to open prostatectomy for prostatic adenoma?
A BPH patient presents with retention of urine. He is Catheterized. Later, he underwent TURP. When would the highest PSA value be?
before catheterization
after catheterization and before TURP
immediately after TURP
2 weeks after TURP
How to manage priapism that occurs during endoscopic surgery?
corporal aspiration
corpora injection with an α-adrenergic agent
corpora injection with an α-adrenergic blocker
no treatment required
What is the initial response of the detrusor muscle to obstruction?
increased intravesical pressure
increased detrusor pressure
increase collagen deposition in the detrusor
detrusor smooth muscle hypertrophy
as adjuncts therapy in BPH cases?
men with storage symptoms
men with ED
failed combination of α-adrenergic blocker and 5α-reductase inhibitor
a & b
a. urethral stricture
bladder stones
BPH
prostatitis syndrome
. What is (are) the indication(s) of antimuscarinic agents and PDEIs
What is (are) true concerning IPSS questionnaire?
it focuses on last month`s symptoms
scores of moderate symptoms suggest surgical treatment if the patient`s quality of life was poor
it has been validated and translated to many languages
all of the above
What can NOT be assessed during DRE?
sacral cord integrity
pelvic hematoma
pelvic floor muscle tenderness
prostatic median lobe hypertrophy
What is false concerning the diagnosis of BPH?
IPSS cannot be used to establish the diagnosis of BPH/LUTS
prostate biopsy is essential in diagnosing BPH and excluding cancers
PSA and uroflowmetry help diagnose the condition
none of the above
What is false regarding BPH symptomatology?
the size of the prostate correlates well to the degree of obstruction
a decrease of 3 points in IPSS is associated with a subjective perception of improvement
median lobe enlargement gives rise to serious obstructive symptoms
bladder trabeculation is not specific for an obstructing prostate
What is the capsular perforation rate in prostate vaporization surgery?
0.2 1%
1.2 2.1%
2.3 3.4%
3.7 5.6%
What is true regarding BPH and androgens?
as a man ages, the responsiveness of prostate cells to androgenic stimuli decreases
adrenal androgens have no role in BPH development
type-1 steroid 5 α-reductase is functionally active in the hair follicle
all of the above
In BPH, the etiology of acute urinary retention includes:
prostatic infarction
prostate infection
bladder overdistention
all of the above
What class(es) of medications decrease(s) IPSS questionnaire points?
calcium channel blockers
antihistamines
antidepressants
cold medications containing pseudoephedrine
Which statement is false regarding TURP syndrome?
occurs because of absorption of non-sodium-containing irrigating fluid
occurs only on using unipolar TURP
results in brain edema due to dilutional hyponatremia
positioning the patient in anti-Trendelenburg helps prevent the syndrome
Preferably, what is the last part of the prostate to be removed while performing TURP?
bladder neck
apex
median lobe
para-collecular