bladder perforation
obturator nerve reflex
vesico-ureteral reflux
terrible bleeding
B. obturator nerve reflex
continue the procedure as perforations at this site do no harm
abort the procedure and leave a urethral catheter
convert tumor removal to open method and repair the defect
perform abdominal exploration and manage accordingly
rarely diagnosed at autopsy
the peak incidence occurs between ages 70 and 80
they occur twice as frequently in men as in women
none of the above
mid prostate to the verumontanum at the 5 and 7 oclock positions
lateral margins of the prostate at the 10 and 2 oclock positions
entire area distal to the urethral crest
area between ejaculatory duct openings and prostatic utricle
leiomyoma
hemangioma
fibroepithelial polyp
lymphangioma
2%
5%
70%
90%
often of high-grade sarcomas
often associated with muscularis propria invasion
due to vesical polyps occluding ureteric orifices
should be resected but not diathermized
obesity
consuming artificial sweeteners
asbestosis
analgesic abuse
infiltrative proximal penile urethral carcinomas
infiltrative distal penile urethral carcinomas
recurrent proximal penile urethral carcinoma after laser resection
T3/N2/M0 at bulbar urethra
frequently found in association with high-grade or extensive TCC
has a rate of progression to muscle invasion of 10-25%
significant areas of CIS are easily missed by routine cystoscopy
treatment begins with TURBT
10%
20%
30%
40%
radical cysto-prostatectomy
anterior pelvic exenteration
bilateral pelvic lymphadenectomy
creation of a urinary diversion
bladder perforation
obturator nerve reflex
vesico-ureteral reflux
terrible bleeding
there will be no target tumor tissue to work on
post-op. hematuria interacts unfavorably with BCG composition
of the risk of systemic absorption and sepsis
of the high risk of BCG reflux to kidneys while bladder irrigation
history of pulmonary TB
total incontinence
immunosuppression
impaired renal function
adenocarcinoma
transitional cell carcinoma
squamous cell carcinoma
basal cell carcinoma
immediately before operation
immediately before incision and post-operative for 1 day
immediately before incision and post-operative for 15 days
immediately before incision and post-operative for 30 days
transitional cell carcinoma
squamous cell carcinoma
adenocarcinoma
small cell carcinoma
the standard treatment is transurethral resection
the prognosis for inverted papilloma is pathetic, with a recurrence rate of approximately 65%
the likelihood of synchronous urothelial carcinoma is 26%
has been shown to harbor p53 gene mutations
ascending urethrography
voiding cystourethrography
MRI
IVU
the lesion is solitary and no associated CIS
physically, a surgical margin of 2-cm can be obtained
the resected area should be far enough from ureteral orifices and the bladder neck
all of the following
upper ureter
middle ureter
lower ureter
comparable
irritative bladder symptoms
obstructive bladder symptoms
palpable suprapubic mass on physical examination
painless profuse hematuria
patients with carcinoma in situ
patients with completely resected solitary tumor
patients with preserved kidney and liver functions after 2 courses of BCG
patients with leiomyosarcoma
obstructive LUTS are common presentations and occur in association with carcinoma in situ
might present as perineal abscesses and fistulae
could be asymptomatic
venereal diseases increase the risk of urethral cancers
undergo cystectomy
try mitomycin c
take a second course of BCG
take a second course of BCG + quinolones
epirubicin
mitomycin c
BCG
none of the above
obstructive uropathy
painless hematuria
pain radiating to the groin
locally advanced tumor
40 - 55%
55 - 70%
70 - 85%
85 - 100%
multifocality
high tumor grade and advanced stage
presence of CIS
all of the above
RB
cyclin A
HRAS
CD-44