What type of cells is implicated most in the pathogenesis of BPS/IC?
histocytes
T lymphocytes
mast cells
B lymphocytes
Correct Answer :
C. mast cells
mast cells.
Related Questions
What is true concerning the treatment of catheter associated bacteriuria?
should be flushed frequently, but no antibiotic is advised
should be treated if febrile UTI has developed
should be treated only if urine culture is positive
should be treated once the catheter is removed
What is the percentage of occurrence of Staphylococcus saprophyticus in symptomatic lower UTIs in young sexually active females?
5%
10%
15%
20%
A 60 yrs. man underwent TURP for, only, obstructive LUTS. Histology of prostate chips reveals prostatitis. What NIH type of prostatitis would it be?
type I
type II
type III
type IV
All of the following etiologies for interstitial cystitis have been theorized, EXCEPT:
allergic, type I hypersensitivity response
pelvic floor dysfunction
up-regulation of histaminergic and muscarinic neuro-receptors
neural hypersensitivity
What is the most important pharmacokinetic property of a drug to cure UTI?
mode of administration
level in the serum
level in the urine
dosage
What are the commonest organisms causing acute epididymitis in males younger than 35 yrs.?
N. gonorrhea and C. trachomatis
E. coli and Pseudomonas species
Mycoplasma genitalium and Ureaplasma species
Trichomonas vaginalis and Gardnerella vaginalis
What is true regarding balanoposthitis?
is best diagnosed by ascending urethrography
occurs mostly in diabetic and immunosuppressed patients
could be due to maceration injury, irritant dermatitis, or Candida
commonly presents with deep inguinal lymphadenopathy
What is true regarding honeymoon cystitis?
is a self-limiting infection where antibiotics are not required
is exclusively for UTI experienced by a girl after sexual intercourse on her wedding night
post-coital voiding has no value in the occurrence of the infection
self-initiated medication helps control the infection
What antimicrobial agent treats UTI and does NOT alter the gut flora?
trimethoprim- sulfamethoxazole
fluoroquinolones
aminoglycosides
nitrofurantoins
What does NOT predispose to acute epididymitis is:
TUR ejaculatory duct
prolonged urethral catheterization
prostatic biopsy
vas ligation
During the initial 3-month period of HIV infection, what would be the best diagnostic lab test?
viral load assay
western blot analysis
southern blot analysis
HIV-1/HIV-2 serology assay
What virus(s) could cause orchitis?
Coxsackie B
Epstein-Barr
varicella
all of the above
What is false regarding Gonorrheal STD in women?
nucleic acid amplification tests are the preferred to diagnose Gonococcal and Chlamydial infections
shows dark yellow, purulent, thick urethral discharge
the most common site of the infection is the endocervix
the incubation period is 2 3 weeks
What is false concerning post UTI renal scarring in pediatrics?
the incidence of scarring following a single episode of febrile UTI is 4.5%
intra-renal reflux is common in convex papillae
scarring and chronic pyelonephritis lead to hypertension in 10-20%
scarring is best detected and followed up by DMSA
Why could pyuria be sterile?
because standard laboratory culture specifications might not be favorable for growth of atypical organisms
because UTI could show fewer than 10 white cells/mm3 in urine
because laboratories may not report significant growth of a defined urinary pathogen
all of the above
What condition causes sterile pyuria?
urethral infection with trichomonas vaginalis
bladder infection with adenovirus
Kawasakis disease
all of the above
What is the likelihood of contracting gonorrheal disease following a single intercourse with an infected woman?
1.7%
7%
17%
71%
What could cause scrotal sinus?
improperly drained hair follicle scrotal abscess
syphilitic orchitis
tuberculous epididymitis
all of the above
Screening for bacteriuria is mostly indicated for:
seniors house residents
ICU patients with indwelling urinary catheters
pregnant women
neurogenic bladder patients on CIC
What is false concerning chronic orchialgia syndrome?
it is a constant or intermittent pain of testes for more than 3 months
could be due to appendix testis torsion-detorsion
could be due to radiculitis resulting from a degenerative lesion in the thoraco-lumber vertebrae
could be a result of entrapment neuropathy of ilioinguinal or genitofemoral nerve
What is the preferred antimicrobial prophylaxis for transrectal prostate biopsy?
aminoglycoside
fluoroquinolone
2nd generation cephalosporin
doxycycline
What is false regarding Herpes simplex (HSV) infection?
characterized by neurovirulence
the incubation period of primary genital herpes is 2 3 weeks
HSV can be isolated in the urine
HSV-1 infection causes urethritis more often than HSV-2 does
What is false concerning esinophilic cystitis?
probably due to antibody/antigen reaction
has no diagnostic findings on cystoscopy
has no specific medical therapy
on histology, Von Brunn`s nests appear invaginating the urothelium into the lamina propria
What is the best statement that describes the action of antiproliferative factor?
inhibits bladder epithelial cell proliferation
inhibits the bladder proliferative growth factors
stimulates the proliferation inhibitory factors
none of the above
In which segmented voided bladder (VB) specimen, the diagnosis of chronic prostatitis is confirmed?
VB1 and VB3
prostatic secretions and the VB3
prostatic secretions and the VB2
prostatic secretions and the VB1
Under which surgical wound classification, does diagnostic cystoscopy under sterile technique fit?
dirty - infected
contaminated
clean - contaminated
clean
Using low-dose prophylactic or suppressive antimicrobials might be an option in treating the following type of prostatitis:
acute bacterial prostatitis presenting with abscess formation
recurrent or refractory chronic bacterial prostatitis
asymptomatic prostatitis with pyuria resistant to common antimicrobials
curiously, chronic inflammatory prostatitis could respond to low-dose suppressive antibiotic
What type of human Herpes virus is implicated in all forms of Kaposi sarcoma?
2
6
7
8
What is (are) the cause(s) of recurrent community acquired UTI in women?
uncontrolled DM
sexual activity with multiple partners
high vaginal receptivity to bacterial adherence
all of the above
What type of scrotal ulcers is painless, punched out, with yellowish grey floor?
tuberculous ulcer
malignant ulcer
gummatous ulcers
traumatic ulcer