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Current Affairs January 2024

What is the correct answer?

4

What is the best statement that describes the action of antiproliferative factor?

A. inhibits bladder epithelial cell proliferation

B. inhibits the bladder proliferative growth factors

C. stimulates the proliferation inhibitory factors

D. none of the above

Correct Answer :

A. inhibits bladder epithelial cell proliferation


self-explanatory.

Related Questions

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4

What is false concerning sepsis syndrome?

A. poor tissue perfusion manifests as hyperlactemia and decreased capillary refill

B. acute oliguria indicates an organ dysfunction and circulatory collapse

C. septic shock is an extreme form of sepsis when hypotension persists despite adequate fluid resuscitation

D. hypotension is a sign of hyperdynamic circulation at an early septic shock

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4

What is true regarding chronic epididymitis symptomatology?

A. pain is dull aching in the scrotum, perineum, inner thighs, and lower abdomen

B. dysuria, frequency, and/or urgency

C. long-standing (> 6 weeks) history of scrotal pain, and tenderness

D. low grade fever, malaise, and urethral discharge

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4

What is false concerning cystitis glandularis?

A. rarely, the urothelial cell nests show a central lumen lined by glandular epithelium

B. In some cases, it may form polypoid masses that mimic urothelial neoplasms

C. It might appear as multinodular exophytic mass seen on cystoscopy

D. cystitis cystica and cystitis glandularis frequently coexist in the same specimen

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4

What is false concerning acute glomerulonephritis?

A. manifested as a sudden onset of hematuria, proteinuria, oliguria, edema, hypertension, and RBC casts in the urine

B. post-streptococcus GN has an incubation period of 1-3 weeks with specific strains of group A beta-hemolytic streptococcus

C. the triad of sinusitis, pulmonary infiltrates, and nephritis, suggests Wegener granulomatosis

D. C3, C4, ESR and antistreptolysin O titer are increased

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4

What are the diagnostic findings on cystometrogram for BPS/IC?

A. discomfort on placing urethral catheter and pain on bladder filling

B. difficulty in zeroing the pressure and diminished response to first cough

C. low filling pressure but high voiding pressure

D. uninhibited bladder contractions with a relative bladder hypotonia

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4

What is true regarding Xanthogranulomatous Pyelonephritis?

A. CT shows the characteristic bear paw sign

B. it is an infected, obstructed, poorly functioning kidney containing stones

C. nephrectomy is the treatment

D. all of the above

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4

A 44 yrs. male presents with recurrent left pyelonephritis and Proteus infection. His kidney is dilated and contains a stone. A renal biopsy showed foamy macrophages with neutrophils and cellular debris. What is the treatment?

A. PCNL after treating the infection

B. cystoscopy and placing a retrograde ureteral stent followed by ESWL

C. perc. nephrostomy and placing antegrade ureteral stent

D. nephrectomy

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4

What is true concerning bacterial colonization in the bladder?

A. is always asymptomatic

B. it shows a serological immune antibody response

C. is a common cause of sterile pyuria

D. typically, at this stage, the body demonstrates bacteriuria

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4

What is false concerning Chlamydia trachomatis urethritis in males:

A. produces yellow whitish, scanty, frothy urethral discharge

B. shows gram (+), extracellular diplococcic

C. infection could be contracted from the spouses eyes

D. responds fairly to azithromycin

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4

What is true concerning the definition of UTI in women, based on culture results from a suprapubic aspirate of urine?

A. any amount of uropathogen grown in culture indicates UTI

B. for cystitis, more than 1000 CFU/mL indicates UTI

C. for pyelonephritis, more than 10,000 CFU/mL indicates UTI

D. for asymptomatic bacteriuria, more than 100,000 CFU/mL indicates UTI

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4

What does NOT predispose to acute epididymitis is:

A. TUR ejaculatory duct

B. prolonged urethral catheterization

C. prostatic biopsy

D. vas ligation

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4

Which of the following is NOT a treatment option for BPS/IC?

A. substitution cystoplasty and continent diversion

B. fulguration of a Hunner`s ulcer or hydrodistention

C. intravesical installation of silver nitrate or dimethyl sulfoxide

D. low dose external beam irradiation

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4

What is false regarding Fournier`s gangrene?

A. is defined as a polymicrobial chronic infection of the perineal, perianal, or genital areas

B. as the disease progresses, branches from the inferior epigastric, deep circumflex iliac, and external pudendal arteries get thrombosed

C. presents as a dark skinned-scrotum, subcutaneous crepitation, and foul smell

D. surgical debridement often spares the testes

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4

When comparing nosocomial to community-acquired UTI, the latter is:

A. 45% are caused by E. coli

B. related to an indwelling urinary catheter in approximately 40% of cases

C. responds fairly to oral antibiotics

D. tends to report higher antibiotic resistance

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4

Irritative LUTS and dyspareunia in postmenopausal women are most likely to be due to:

A. giggle incontinence

B. estrogen deficiency

C. cystitis glandularis

D. cystitis cystica

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4

What is false concerning inverted papilloma of the bladder?

A. It is an endophytic tumor of the transitional urothelium

B. harbors p53 gene mutations

C. presents with hematuria, dysuria, and irritative voiding

D. the lesion requires transurethral resection

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4

What is false regarding biopsy-taking from interstitial cystitis bladder?

A. no pathognomonic histology for interstitial cystitis

B. basically, biopsies are performed to exclude carcinomas and other varieties of cystitis

C. diagnostic biopsies include the presence of discrete micro-ulcers and increased numbers of mast cells in the detrusor muscle or submucosa

D. none of the above

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4

What is the ideal antibiotic class for self-start therapy on treating recurrent cystitis in a 32 yrs. married woman?

A. aminopenicillins

B. fluoroquinolones

C. aminoglycosides

D. nitrofurantoins

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4

Which of the following factors increases the risk of UTI due to promotion of microbial colonization?

A. neurogenic bladder

B. the use of spermicide

C. urinary catheterization

D. fecal incontinence

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4

What is true concerning granulomatous inflammation of the prostate?

A. is a common cause of elevated PSA level

B. might follow BCG treatment

C. is sequelae of untreated type III-b prostatitis

D. shows homogenous enhancement following Gd-DTPA on prostate MRI

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4

What is the most significant biological difference in women susceptibility to UTI?

A. adherence of bacteria to vaginal cells

B. vaginal dryness

C. O serogroup

D. vaginal pH

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4

What condition causes sterile pyuria?

A. urethral infection with trichomonas vaginalis

B. bladder infection with adenovirus

C. Kawasakis disease

D. all of the above

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4

What is the likelihood of contracting gonorrheal disease following a single intercourse with an infected woman?

A. 1.7%

B. 7%

C. 17%

D. 71%

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4

What virus(s) could cause orchitis?

A. Coxsackie B

B. Epstein-Barr

C. varicella

D. all of the above

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4

What is false regarding malakoplakia?

A. is an uncommon granulomatous disease that affect the skin and/or urinary bladder

B. it might be due to a disturbed function of B lymphocytes

C. characterized by the presence of basophilic inclusion structure (Michaelis-Gutmann body)

D. it might be due to a defective phagolysosomal activity of monocytes or macrophages

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4

What are the most commonly affected organs by genitourinary tuberculosis?

A. kidneys, prostate and epididymi

B. bladder, ureters and renal pelvis

C. vasa, scrotum and adrenals

D. testes, bladder neck and seminal vesicles

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4

A 48 yrs. woman presents with recurrent cystitis. Cystoscopy showed a raised bladder lesion. Biopsies from the lesion reveals Von Hansemann histiocytes, and Michaelis-Gutmann bodies. What is the treatment?

A. sulfonamide for several months

B. TUR of the bladder lesion followed by proper staging

C. radical cystectomy and urinary diversion

D. intravesical installation of mitomycin without irradiation

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4

What is false concerning the cystoscopic findings of interstitial cystitis?

A. Hunner`s ulcers are multiple ulcerative patches surrounded by mucosal congestion on the dome or lateral walls

B. ulcers might get distorted after overdistention, because discrete areas of mucosal scarring rupture during the procedure

C. in non-ulcerative type, overdistention demonstrates glomerulations on the dome and lateral walls

D. overdistention results in mucosal tears and submucosal hemorrhage

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4

What is false concerning foreign body cystitis?

A. most commonly due to indwelling catheters

B. the areas of inflammation are usually confined to the lateral walls or the dome of the bladder

C. radiographic changes are nonspecific or present as bullous edema

D. indwelling catheters are associated with squamous cell carcinoma of the bladder

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4

Why could pyuria be sterile?

A. because standard laboratory culture specifications might not be favorable for growth of atypical organisms

B. because UTI could show fewer than 10 white cells/mm3 in urine

C. because laboratories may not report significant growth of a defined urinary pathogen

D. all of the above