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Current Affairs January 2024

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4

What is the most important pharmacokinetic property of a drug to cure UTI?

A. mode of administration

B. level in the serum

C. level in the urine

D. dosage

Correct Answer :

C. level in the urine


the therapeutic level of the drug in the urine is the most important to eradicate the infection.

Related Questions

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4

What is true concerning BPS/IC?

A. the onset of symptoms is insidious

B. the lesion has no proven relation to bladder cancer

C. if left untreated, the bladder will turn small, contracted, with submucosal calcifications

D. a single positive urine culture refutes the diagnosis

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4

What is true regarding acute pyelonephritis?

A. a cause of obstruction should be sought

B. PCN is placed to decompress the kidney and preserve renal function

C. blood-born staphylococci are commoner than ascending E.coli infections

D. blood and urine cultures must dictate the antibiotic choice from day 1

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4

What is false concerning inverted papilloma of the bladder?

A. It is an endophytic tumor of the transitional urothelium

B. harbors p53 gene mutations

C. presents with hematuria, dysuria, and irritative voiding

D. the lesion requires transurethral resection

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4

What is false concerning corpora amylacea of the prostate?

A. are premalignant, and found in 1-6% of prostate biopsies

B. are small hyaline masses of unknown significance found in the prostate gland

C. they are degenerate cells or thickened secretions in the prostate ducts

D. might appear as prostate calcifications on X-ray KUB

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4

Which of the following conditions is NOT associated with interstitial cystitis?

A. inflammatory bowel disease

B. rheumatoid arthritis

C. systemic lupus erythematosus

D. fibromyalgia

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4

A 60 yrs. man underwent TURP for, only, obstructive LUTS. Histology of prostate chips reveals prostatitis. What NIH type of prostatitis would it be?

A. type I

B. type II

C. type III

D. type IV

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4

Which of the following conditions does NOT cause bacterial persistence?

A. perivesical abscess with fistula to bladder

B. acute tubular necrosis

C. renal papillary necrosis

D. xanthogranulomatous pyelonephritis

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4

What antimicrobial agent treats UTI and does NOT alter the gut flora?

A. trimethoprim- sulfamethoxazole

B. fluoroquinolones

C. aminoglycosides

D. nitrofurantoins

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4

What is true concerning ovarian vein syndrome?

A. manifests as recurrent renal colics due to ureteral obstruction

B. treatment is surgical mobilization of ureter and ligation of the vein

C. commonly, occurs at the left side

D. the pain worsens on sitting upright and during pregnancy

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4

What is false regarding pediatric renal parenchyma scarring?

A. chronic pyelonephritis and HTN lead to ESRD in 10% of the cases

B. neonatal symptoms of UTI are vague and non-specific, that delay the diagnosis and end in more scarring

C. despite adequate treatment, scarring continues after an attack of pyelonephritis as a chronic immune reaction against renal tubules

D. neonates have low intrarenal pelvic pressure, that predisposes to ascending infections

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4

What is false in the treatment and prevention of STDs?

A. antibiotic therapy is recommended for affected individuals with documented trichomonal infection and sexual partners even if asymptomatic

B. empirical treatment for gonococcal urethritis should cover chlamydia trachomatis

C. consistent and proper usage of condoms is estimated to prevent HIV transmission by approximately 80 to 95%

D. vaccinations are available for the prevention of human papillomavirus, N. gonorrhea, chlamydia trachomatis

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4

What is true concerning the definition of UTI in women, based on culture results from a suprapubic aspirate of urine?

A. any amount of uropathogen grown in culture indicates UTI

B. for cystitis, more than 1000 CFU/mL indicates UTI

C. for pyelonephritis, more than 10,000 CFU/mL indicates UTI

D. for asymptomatic bacteriuria, more than 100,000 CFU/mL indicates UTI

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4

What is false regarding the etiology and treatment of orchialgia syndrome?

A. small indirect inguinal hernia may irritate the genital branch of genitofemoral nerve causing orchialgia

B. might respond to a selective nerve block

C. the recommended treatment is orchiectomy with implantation of a testicular prosthesis

D. psychotherapy and stress management might alleviate the pain

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4

Which of the following is NOT a treatment option for BPS/IC?

A. substitution cystoplasty and continent diversion

B. fulguration of a Hunner`s ulcer or hydrodistention

C. intravesical installation of silver nitrate or dimethyl sulfoxide

D. low dose external beam irradiation

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4

What is the commonest cause of relapsing UTI in males?

A. chronic epididymitis

B. epididymo-orchitis

C. chronic bacterial prostatitis

D. venereal cysto-urethritis

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4

What is false concerning esinophilic cystitis?

A. probably due to antibody/antigen reaction

B. has no diagnostic findings on cystoscopy

C. has no specific medical therapy

D. on histology, Von Brunn`s nests appear invaginating the urothelium into the lamina propria

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4

What is false concerning renal hydatid cysts?

A. might rupture into the collecting system causing (hydatiduria)and renal colic

B. are formed by the eggs of the tapeworm Echinococcus granulosus

C. most cysts are asymptomatic but might manifest as flank mass, dull pain, or hematuria

D. the most reliable diagnostic test uses partially purified hydatid arc 5 antigens in a double-diffusion test

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4

What is the best statement that describes the action of antiproliferative factor?

A. inhibits bladder epithelial cell proliferation

B. inhibits the bladder proliferative growth factors

C. stimulates the proliferation inhibitory factors

D. none of the above

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4

What is the proper term to describe high bacterial count in urine without pus?

A. asymptomatic bacteriuria

B. sterile pyouria

C. bacterial colonization

D. unresolved bacteriuria

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4

What condition(s) could occur in schistosomal ureter?

A. beading of the lower ureteral segment

B. ureteral fibrosis and calcifications of the distal ureter

C. stricture at the uretero-vesical junction

D. all of the above

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4

What is false concerning post UTI renal scarring in pediatrics?

A. the incidence of scarring following a single episode of febrile UTI is 4.5%

B. intra-renal reflux is common in convex papillae

C. scarring and chronic pyelonephritis lead to hypertension in 10-20%

D. scarring is best detected and followed up by DMSA

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4

Which statement best defines reinfection?

A. a new episode of UTI caused by different species or occurring at long intervals

B. recurrent UTIs caused by the same organism in each instance, classically, at close intervals

C. recurrent UTIs due to failure of medical therapy to eradicate the infection

D. recurrent UTIs due to a persistent pathology that is obstinate to surgery

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4

Which of the following does NOT cause unresolved bacteriuria?

A. giant staghorn stone

B. perivesical abscess with fistula to the bladder

C. bacterial resistance

D. self-inflicted infection

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4

In males, HIV infection increases the incidence of the following genitourinary tumors:

A. testicular

B. renal

C. penile

D. all of the above

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4

Which of the following factors increases the risk of UTI due to promotion of microbial colonization?

A. neurogenic bladder

B. the use of spermicide

C. urinary catheterization

D. fecal incontinence

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4

What is (are) the complication(s) of sexually transmitted infections?

A. pelvic inflammatory disease

B. lymphogranuloma venereum

C. infertility

D. all of the above

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4

Patients with bladder pain syndrome have:

A. a history of repeated urologic and/or gynecologic procedures

B. 10 fold higher incidence of childhood voiding problems

C. 4 fold higher incidence of anxiety-depression syndrome

D. 6 fold higher incidence of psychosomatic disorders

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4

What type of bladder cells secretes antiproliferative factor?

A. bladder epithelial cells

B. type C nerve endings in the bladder

C. type A delta nerve endings in the bladder

D. the innermost longitudinal fibres of detrusor muscle

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4

What does NOT predispose to acute epididymitis is:

A. TUR ejaculatory duct

B. prolonged urethral catheterization

C. prostatic biopsy

D. vas ligation

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4

What is false concerning epididymitis?

A. should be distinguished from testicular torsion in the emergency setting

B. viral epididymitis is commoner in the elderly

C. chronic epididymitis might complicate BPH

D. chronic epididymitis might require epididymectomy