. What is NOT an indication for simple nephrectomy?
symptomatic chronic renal infection with poor function
some cases of renovascular hypertension
symptomatic calculus disease with poor renal function
D. symptomatic calculus disease with poor renal function
most classic AMLs eventually undergo malignant transformation to sarcomatoid and epithelioid AML
the preferred treatment is nephroureterectomy followed by active surveillance
angiographic embolization and/or nephron-sparing surgery is advised for symptomatic AMLs greater than 4 cm
extra-renal sites include the pancreas, salivary glands, and thyroids
renal oncocytoma
multiloculated cystic nephromas
metanephric adenoma
adenoma with clear cell
type II DM, especially in males
hypertension
obesity, especially in females
cigarette smoking
. The second most common RCC subtype is:
collecting duct b. clear cell
papillary
chromophobe
. In RCC, ipsilateral adrenal metastasis occurs in:
0.3 - 2%
2 - 10%
11 - 18%
. What is false concerning targeted molecular therapy?
is a personalized medical therapy devised to meet each persons individual needs for cancer`s specifications
treats cancer by interrupting unique molecular abnormalities that drive cancer growth
some cancer types have different molecular targets
ARPKD accounts for 5% of ESRD in children
more than one-half of patients with ARPKD require kidney transplant before age 20 years
ADPKD is a common cause of ESRD
uncommonly, juvenile nephronophthisis causes ESRD in children
hepatic cysts are the most common extra-renal manifestation
might experience cyst hemorrhage, renal infection, or nephrolithiasis
typically, complain of flank pain or intermittent hematuria in the early twenties
hypertension and CRF commonly occur in the fifth decade of life
the central scar on CT or MRI, and the spoke-wheel pattern of vessels on angiograms are not specific to oncocytoma
calcification, necrosis, and hemorrhage are rare in oncocytomas
it is thought to arise from the basement membrane of proximal convoluted tubules
treatment is partial nephrectomy or tumor excision
autosomal dominant polycystic kidney disease (ADPKD)
developmental cystic renal disease
inherited cystic renal disease
systemic disease with associated renal cysts
autosomal recessive polycystic kidney disease
autosomal dominant polycystic kidney disease
multicystic dysplastic kidney disease
juvenile nephronophthisis
fibrosarcoma
leiomyosarcoma
carcinoid
adult Wilm`s tumor
. What is NOT an indication for simple nephrectomy?
symptomatic chronic renal infection with poor function
some cases of renovascular hypertension
symptomatic calculus disease with poor renal function
glomerulocystic kidney disease
developmental cystic renal disease
Juvenile nephronophthisis
medullary cystic kidney disease
. What is the relapse rate for completely resected RCC after radical nephrectomy?
1- 10%
10 - 20%
20 - 30%
is > 90% in Bosniak type IV renal cysts
in patients receiving renal transplants for polycystic kidney disease is 48% higher than that expected in the general population
all of the above
simple renal cysts might turn malignant in < 4% of cases
RCC
AML
teratoma
any of the above
papillary RCC
renal metastases
renal oncocytoma
renal xanthogranuloma
cyst aspiration and sclerosis
partial nephrectomy
endoscopic marsupialization and fulguration of the cyst
administration of TKIs
progress to ESRD in the sixth decade of life
hypertension is seen in 80% of patients with ADPKD aged 20-34 years
aortic valve stenosis in 25%
manifestations are more significant in patients with the PKD2 genotype
physically active patients with good performance status
extirpation of the primary tumor
long disease-free interval between initial nephrectomy and the emergence of secondaries
all of the above
. Metastatic tumors to the kidney are common from all of the following organs, EXCEPT:
lungs
thyroid
breasts
papillary subtype of RCC has a tendency to multifocality
chromosome 13 alterations are common in the development of clear cell renal carcinoma
a solid mass on CT that enhances more than 15 HU is suggestive of RCC
bilateral involvement in RCC either synchronously or metachronously occurs in 2% to 4% of patients
70 - 85%
55 - 70%
40 - 55%
25 - 40%
. What is false concerning imaging studies for preoperative evaluation of RCC case?
in case of bone pain or elevated serum calcium and/or alkaline phosphatase levels, an isotopic bone scan is required
renal arteriography accurately localizes central scaring and tumor necrosis
trans-esophageal echocardiography helps assess vena caval and right atrial tumor thrombi
multiloculated cystic nephromas
angiomyolipoma
metanephric adenoma
adenoma with clear cell
. What is the most common histologic subtype of renal sarcomas?
rhabdomyosarcoma
nephrosarcoma
leiomyosarcoma
hyperattenuating renal cyst
solitary renal cyst
uncomplicated renal cyst
focal renal cyst
. Manifestations of paraneoplastic syndrome associated with RCC include all of the following, EXCEPT:
anemia and erythrocytosis
hepatic dysfunction and elevated human chorionic gonadotropin levels
hypocalcemia
RCC occurs in < 5% of patients with tuberous sclerosis
in glomerulocystic kidney disease, renal tumors are typically solitary, large, with central necrosis
in Von Hippel-Lindau syndrome, renal tumors are frequently bilateral and multicentric
in acquired cystic disease, tumors are commonly bilateral, and metastatic in 15% of cases