d. 30 - 40%
. What is false concerning imaging studies for preoperative evaluation of RCC case?
in case of bone pain or elevated serum calcium and/or alkaline phosphatase levels, an isotopic bone scan is required
renal arteriography accurately localizes central scaring and tumor necrosis
trans-esophageal echocardiography helps assess vena caval and right atrial tumor thrombi
Correct Answer :
B. in case of bone pain or elevated serum calcium and/or alkaline phosphatase levels, an isotopic bone scan is required
renal arteriography, although no longer routinely necessary before radical nephrectomy, is useful in showing arterialization of tumor thrombi.
Related Questions
What is false concerning renal cancers?
papillary subtype of RCC has a tendency to multifocality
chromosome 13 alterations are common in the development of clear cell renal carcinoma
a solid mass on CT that enhances more than 15 HU is suggestive of RCC
bilateral involvement in RCC either synchronously or metachronously occurs in 2% to 4% of patients
Which of the following conditions carries the best prognosis?
acquired cystic renal disease
juvenile nephronophthisis
medullary sponge kidney
bilateral multicystic dysplastic kidney
What is false concerning end-stage renal disease (ESRD)?
ARPKD accounts for 5% of ESRD in children
more than one-half of patients with ARPKD require kidney transplant before age 20 years
ADPKD is a common cause of ESRD
uncommonly, juvenile nephronophthisis causes ESRD in children
What is false concerning renal oncocytoma?
the central scar on CT or MRI, and the spoke-wheel pattern of vessels on angiograms are not specific to oncocytoma
calcification, necrosis, and hemorrhage are rare in oncocytomas
it is thought to arise from the basement membrane of proximal convoluted tubules
treatment is partial nephrectomy or tumor excision
What does determine the renal function status after partial nephrectomy of a single kidney?
the quality of the kidney and renal function prior to surgery
the quantity of vascularized parenchymal mass preserved after excision
the tumor
warm ischemia time
In RCC cases where IVC involvement with tumor thrombi are suspected, venacavography:
is the first and most reliable radiologic examination to study IVC thrombi
is reserved for patients with equivocal MRI or CT findings
is obsolete and has fallen out of use
carries a risk of IVC terrible bleeding that outweighs the diagnostic merits
What type of Bosniak renal cysts accompanies tumor masses in 5% of cases?
I
II
III
IV
In renal mass(es), the main indication to take a renal biopsy is the suspicion of:
papillary RCC
renal metastases
renal oncocytoma
renal xanthogranuloma
CT shows a renal mass with calcifications associated with fat. What could the lesion be?
RCC
AML
teratoma
any of the above
What is true regarding ADPKD patients?
progress to ESRD in the sixth decade of life
hypertension is seen in 80% of patients with ADPKD aged 20-34 years
aortic valve stenosis in 25%
manifestations are more significant in patients with the PKD2 genotype
Which RCC subtype is most likely to benefit from targeted molecular therapy?
clear cell
chromophobe
papillary
renal medullary
Inherited renal cystic disease(s) include(s) the following:
glomerulocystic kidney disease (GCKD)
Juvenile nephronophthisis (JNPHP)
medullary cystic kidney disease
all of the above
After radical nephrectomy for organ-confined RCC, what is (are) the recommended surveillance radiologic examination(s)?
chest X-ray and abdominal ultrasonography every 3 months for the first year, and then annually for 3 years
annual chest X-ray for 3 years
abdominal and chest CT every 6 months for the first year, and then annually for 3 years
no radiological examination required
On histological examination of a resected renal tumor, positive staining for human melanoma black (HMB)-45 is a distinctive and diagnostic feature for:
multiloculated cystic nephromas
angiomyolipoma
metanephric adenoma
adenoma with clear cell
The etiology of renal cysts includes all of the following, EXCEPT:
autosomal dominant polycystic kidney disease (ADPKD)
developmental cystic renal disease
inherited cystic renal disease
systemic disease with associated renal cysts
Which of the following renal tumors carries the best prognosis?
fibrosarcoma
leiomyosarcoma
carcinoid
adult Wilm`s tumor
d. unilateral RCC with a functioning opposite kidney, but at risk for future impairment
. What is the relapse rate for completely resected RCC after radical nephrectomy?
1- 10%
10 - 20%
20 - 30%
What is false concerning metanephric adenoma?
radiographically, it is indistinguishable from RCC
has a female predominance
has a benign clinical course
has a peak incidence in the third decade of life
Regarding simple renal cysts, fluid attenuation on non-contrast CT series is:
< - 10 HU
< - 20 HU
< 10 HU
< 20 HU
Routine metastatic evaluation in RCC cases should include all of the following, EXCEPT:
abdominal CT
chest X-ray
renal function test
liver function test
What is (are) the risk factor(s) for developing simple renal cysts?
male gender
hypertension
renal insufficiency
all of the above
What is false concerning renal malignancy?
RCC occurs in < 5% of patients with tuberous sclerosis
in glomerulocystic kidney disease, renal tumors are typically solitary, large, with central necrosis
in Von Hippel-Lindau syndrome, renal tumors are frequently bilateral and multicentric
in acquired cystic disease, tumors are commonly bilateral, and metastatic in 15% of cases
d. CT can detect renal vein involvement in 82-95% of cases and vena caval involvement in 95-100% of cases
. In RCC, ipsilateral adrenal metastasis occurs in:
0.3 - 2%
2 - 10%
11 - 18%
Which of the following is NOT a risk factor for RCC?
type II DM, especially in males
hypertension
obesity, especially in females
cigarette smoking
What can NOT be a manifestation of a renal tumor?
right hydrocele
left varicocele
painless hematuria
hypertension
On ultrasonography, what are the percentages of incidentally discovered renal masses that will later be malignant on further workup?
70 - 85%
55 - 70%
40 - 55%
25 - 40%
d. prior to kidney transplant
. What is an indication for radical nephrectomy?
a 6-cm, polar tumor
bilateral RCC
locally advanced RCC
d. renal vein thrombi can be resected after incising the vein between 2 vascular clamps
. Manifestations of paraneoplastic syndrome associated with RCC include all of the following, EXCEPT:
anemia and erythrocytosis
hepatic dysfunction and elevated human chorionic gonadotropin levels
hypocalcemia
Antenatal sonography is the diagnostic tool for the following condition:
glomerulocystic kidney disease
developmental cystic renal disease
Juvenile nephronophthisis
medullary cystic kidney disease
d. neurosarcoma
. What is false concerning targeted molecular therapy?
is a personalized medical therapy devised to meet each persons individual needs for cancer`s specifications
treats cancer by interrupting unique molecular abnormalities that drive cancer growth
some cancer types have different molecular targets