What is true regarding renal angiomyolipoma (AML)?
most classic AMLs eventually undergo malignant transformation to sarcomatoid and epithelioid AML
the preferred treatment is nephroureterectomy followed by active surveillance
angiographic embolization and/or nephron-sparing surgery is advised for symptomatic AMLs greater than 4 cm
extra-renal sites include the pancreas, salivary glands, and thyroids
Correct Answer :
C. angiographic embolization and/or nephron-sparing surgery is advised for symptomatic AMLs greater than 4 cm
despite that the best management of AML is a matter of controversy, angiographic embolization and/or nephron-sparing surgery is advised for symptomatic AMLs greater than 4 cm.
Related Questions
Which of the following conditions carries the worst prognosis?
acquired cystic renal disease
juvenile nephronophthisis
medullary sponge kidney
bilateral multicystic dysplastic kidney
Antenatal sonography is the diagnostic tool for the following condition:
glomerulocystic kidney disease
developmental cystic renal disease
Juvenile nephronophthisis
medullary cystic kidney disease
On ultrasonography, what are the percentages of incidentally discovered renal masses that will later be malignant on further workup?
70 - 85%
55 - 70%
40 - 55%
25 - 40%
What is the most common cause of genetic ESRD in children?
autosomal recessive polycystic kidney disease
autosomal dominant polycystic kidney disease
multicystic dysplastic kidney disease
juvenile nephronophthisis
What is the treatment of a 3-cm renal mass suggestive of RCC adjacent to a huge renal cyst?
cyst aspiration and sclerosis
partial nephrectomy
endoscopic marsupialization and fulguration of the cyst
administration of TKIs
d. neurosarcoma
. What is false concerning targeted molecular therapy?
is a personalized medical therapy devised to meet each persons individual needs for cancer`s specifications
treats cancer by interrupting unique molecular abnormalities that drive cancer growth
some cancer types have different molecular targets
d. melanoma
. The second most common RCC subtype is:
collecting duct b. clear cell
papillary
chromophobe
What is true regarding ADPKD patients?
progress to ESRD in the sixth decade of life
hypertension is seen in 80% of patients with ADPKD aged 20-34 years
aortic valve stenosis in 25%
manifestations are more significant in patients with the PKD2 genotype
According to Fuhrmans classification system for nuclear grading in RCC, nuclear size of 20 μg with irregular outline and prominent nucleoli is grade:
1
2
3
4
What can NOT be a manifestation of a renal tumor?
right hydrocele
left varicocele
painless hematuria
hypertension
Inherited renal cystic disease(s) include(s) the following:
glomerulocystic kidney disease (GCKD)
Juvenile nephronophthisis (JNPHP)
medullary cystic kidney disease
all of the above
d. all of the above
. What is the most common histologic subtype of renal sarcomas?
rhabdomyosarcoma
nephrosarcoma
leiomyosarcoma
Regarding simple renal cysts, fluid attenuation on non-contrast CT series is:
< - 10 HU
< - 20 HU
< 10 HU
< 20 HU
What type of Bosniak renal cysts accompanies tumor masses in 5% of cases?
I
II
III
IV
What is false concerning end-stage renal disease (ESRD)?
ARPKD accounts for 5% of ESRD in children
more than one-half of patients with ARPKD require kidney transplant before age 20 years
ADPKD is a common cause of ESRD
uncommonly, juvenile nephronophthisis causes ESRD in children
d. renal vein thrombi can be resected after incising the vein between 2 vascular clamps
. Manifestations of paraneoplastic syndrome associated with RCC include all of the following, EXCEPT:
anemia and erythrocytosis
hepatic dysfunction and elevated human chorionic gonadotropin levels
hypocalcemia
d. 19 - 26%
. What is false regarding radical nephrectomy operation?
nodal involvement doesn`t influence prognosis
renal artery should be ligated before the vein to avoid kidney ballooning
cardiopulmonary bypass with deep hypothermic circulatory arrest is performed in patients with supra-diaphragmatic tumor thrombi
d. unilateral RCC with a functioning opposite kidney, but at risk for future impairment
. What is the relapse rate for completely resected RCC after radical nephrectomy?
1- 10%
10 - 20%
20 - 30%
In RCC cases where IVC involvement with tumor thrombi are suspected, venacavography:
is the first and most reliable radiologic examination to study IVC thrombi
is reserved for patients with equivocal MRI or CT findings
is obsolete and has fallen out of use
carries a risk of IVC terrible bleeding that outweighs the diagnostic merits
In renal mass(es), the main indication to take a renal biopsy is the suspicion of:
papillary RCC
renal metastases
renal oncocytoma
renal xanthogranuloma
In a localized RCC, local recurrence after tumor ablation therapy is managed by any of the following options, EXCEPT:
repeat ablation
active surveillance
salvage surgery
radical nephrectomy
What type of renal adenomas is a precursor to papillary RCC?
adenoma with clear cell
papillary adenoma
metanephric adenoma
none of the above
What is the proper terminology of a renal cyst with the following characteristics: well-marginated, anechoic, with thin visible back wall, positive posterior acoustic enhancement, no septations, and no calcifications?
hyperattenuating renal cyst
solitary renal cyst
uncomplicated renal cyst
focal renal cyst
What is true regarding cancer incidence in renal cystic diseases?
is > 90% in Bosniak type IV renal cysts
in patients receiving renal transplants for polycystic kidney disease is 48% higher than that expected in the general population
all of the above
simple renal cysts might turn malignant in < 4% of cases
On histological examination of a resected renal tumor, the presence of multiple mitochondria observed on electron microscopy is diagnostic for:
renal oncocytoma
multiloculated cystic nephromas
metanephric adenoma
adenoma with clear cell
What is false regarding multiloculated cystic nephromas?
they follow a benign clinical course
they have a bimodal age distribution
they are more common in men than in women
none of the above
What is false concerning renal oncocytoma?
the central scar on CT or MRI, and the spoke-wheel pattern of vessels on angiograms are not specific to oncocytoma
calcification, necrosis, and hemorrhage are rare in oncocytomas
it is thought to arise from the basement membrane of proximal convoluted tubules
treatment is partial nephrectomy or tumor excision
d. prior to kidney transplant
. What is an indication for radical nephrectomy?
a 6-cm, polar tumor
bilateral RCC
locally advanced RCC
The likelihood of malignancy in category IIF (indeterminate) renal cysts is:
20%
30%
40%
50%
d. hypertension
. Metastatic tumors to the kidney are common from all of the following organs, EXCEPT:
lungs
thyroid
breasts