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Current Affairs January 2024

What is the correct answer?

4

Solid lesions in the seminal vesicles are most likely to be a result of:

A. imperfect prostate biopsies

B. immature teratoma

C. schistosomiasis

D. liposarcoma

Correct Answer :

C. schistosomiasis


self-explanatory.

Related Questions

What is the correct answer?

4

Solid lesions in the seminal vesicles are most likely to be a result of:

A. imperfect prostate biopsies

B. immature teratoma

C. schistosomiasis

D. liposarcoma

What is the correct answer?

4

In descending order, the commonest complications of external beam radiation therapy for prostate cancer are:

A. urethral stricture, impotence, and rectal bleeding

B. impotence, rectal bleeding, and urethral stricture

C. impotence, urethral stricture, and rectal bleeding

D. rectal bleeding, impotence, and urethral stricture

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4

What is false regarding the histology of prostatic cancers?

A. benign glands are different from malignant glands, as they contain basal cells

B. adenosis in the transitional zone carries 15% increase in cancer risk

C. the prostate has no discrete histologic capsule

D. intraductal carcinoma is morphologically worse than high-grade PIN and is typically associated with high-grade carcinoma

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4

All of the following modalities are used as salvage therapies after failing radiation therapy for prostate cancer treatment, EXCEPT:

A. cryotherapy

B. chemotherapy

C. brachytherapy

D. radical prostatectomy

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4

In descending order, to where do prostate cancers metastasize?

A. lymph nodes, bone, lung, bladder, liver, and adrenal glands

B. bone, lung, lymph nodes, liver, bladder, and adrenal glands

C. lung, liver, lymph nodes, bone, adrenal glands, and bladder

D. liver, lung, bone, lymph nodes, bladder, and adrenal glands

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4

What are the clinical parameters of tissue ablation achieved by cryotherapy for cancer cells destruction?

A. the number of freezing cycles

B. the lowest temperature achieved

C. the existence of regional heat sinks

D. all of the above

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4

What is the proper pre-treatment risk stratification of prostate cancer for a patient with T2a, PSA < 11 ng/mL, and no Gleason score > 6?

A. low risk

B. intermediate risk

C. high risk

D. data not adequate

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4

What is false concerning TRUS prostatic biopsy?

A. a 12-core biopsy is the standard

B. in preparation for the procedure, a self-administered enema is suggested

C. sepsis might complicate the procedure

D. the biopsy path is best visualized in the coronal plane

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4

For prostate cancer patients, what do Partin tables predict?

A. survival rate

B. pathologic stage

C. extracapsular extension

D. lymph node involvement

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4

Fill the blanks: on treating prostate cancer patients, the median time from PSA failure to the development of metastatic disease after radical prostatectomy is approximately (…) yrs. and from the time of metastases to death is approximately (…) yrs..

A. 4, 2 respectively

B. 8, 5 respectively

C. 6, 3 respectively

D. 7, 4 respectively

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4

What is false concerning antiandrogen class of prostate cancer medications?

A. commonly used in combination with a GnRH agonist

B. less effective than medical or surgical castration

C. not recommended for localized prostate cancer

D. inhibits various cytochrome P-450 enzymes

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4

Screening for prostate cancer is recommended for men who are:

A. at average risk, aging 50 yrs., and have at least a 10-year life expectancy

B. aging 40 yrs., and had a first-degree relative diagnosed with prostate cancer before age 65

C. aging 40 yrs., African Americans

D. all of the above

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4

Regarding treating prostate cancer patients, watchful waiting is a reasonable option for:

A. patients who have a life expectancy ≤ 10 yrs. and/or well to moderately differentiated cancer

B. ≥ 70 yrs. of age

C. PSA < 10 ng/mL, ratio < 0.22

D. patients with good performance status

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4

What class of prostate cancer medications causes an initial increase in LH, FSH levels and consequently a rise in testosterone level for few weeks?

A. GnRH agonists

B. antiandrogens

C. antimicrotubular

D. bisphosphonates

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4

Genetically, increased risk of prostate cancer has been found in men with:

A. variants in the 8q24 region on chromosome 8, in sporadic cases

B. alterations on chromosome 1, chromosome 17, and the X chromosome, in some familial cases

C. the human prostate cancer gene is on the X chromosome

D. all are true

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4

What is true surrounding PSA?

A. black individuals produce more PSA than whites

B. ejaculation can lead to a false decrease in PSA

C. pro-PSA is the serum proactive form of PSA molecule

D. prostate cancer cells make more PSA than normal prostate tissues do

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4

What is true concerning TRUS prostatic biopsy?

A. hematospermia might persist for 4 6 weeks after taking biopsies

B. quinolone antibiotics prophylaxis eliminate possible infections

C. the right lateral decubitus position is commonly preferred

D. only hypoechoic lesions should be biopsied

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4

What is false concerning Gleason scoring system for prostate cancers?

A. ranges from 0 -10 based on a histologic evaluation of tumor specimens

B. based on the 2 most common histologic patterns

C. greatly relies on the skills and experience of the pathologist

D. a score of 7 indicates a moderate-grade or moderately differentiated tumor

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4

Which factor(s) determine(s) the return to normal erectile function after radical retropubic prostatectomy?

A. the age of the patient

B. preoperative potency status

C. extent of nerve-sparing surgery

D. all of the above

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4

Regarding chemotherapy for prostate cancers, nonsteroidal antiandrogens will result in:

A. elevated LH, elevated testosterone, elevated estrogen

B. elevated LH, elevated testosterone, declined estrogen

C. declined LH, declined testosterone, elevated estrogen

D. declined LH, elevated testosterone, declined estrogen

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4

Ectopic expression of PSA occurs in all of the following, EXCEPT:

A. thyroid gland

B. breast tissue

C. adrenal glands

D. renal carcinomas

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4

What is the primary mechanism of prostate tissue ablation using high-intensity focused ultrasound?

A. disruption of protein synthesis

B. coagulative necrosis

C. cell wall destruction

D. DNA damage

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4

What is the commonest complication of high-intensity focused ultrasound on treating localized prostate cancer?

A. temporary incontinence

B. vasculogenic impotence

C. urinary retention

D. hyper-reflexive detrusor

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4

What condition does NOT appear as a hypoechoic lesion in the prostate on TRUS?

A. prostate cancer

B. corpora amylacea

C. transitional zone

D. tuberculous prostatitis

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4

What is the major advantage of neoadjuvant androgen deprivation before radical prostatectomy on treating clinical stages (cT1-T2) prostate cancers?

A. reduces positive surgical margins

B. reduces local recurrence

C. has no proven advantage

D. reduces cardiac complications

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4

Which factor is closely related to the return to urinary continence function after radical retropubic prostatectomy?

A. pathologic tumor stage

B. performing nerve-sparing surgery

C. patient`s age

D. performing internal sphincter micro-dissection

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4

What is false regarding prostate adenocarcinoma in the peripheral zone?

A. 85% of prostate adenocarcinomas are located in the peripheral zone

B. 15% of them are multifocal

C. they tend to extend outside the prostate through the perineural space

D. the presence of perineural invasion does not worsen the prognosis

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4

Genetically, what are the changes associated with poor survival in prostate cancer patients?

A. loss of one or both copies of the tumor suppressor gene PTEN

B. TMPRSS2ERG chromosome fusion

C. P53 mutations and overexpression of MYC

D. all of the above

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4

Which of the following tests has the highest positive predictive value for prostate cancer?

A. PSA

B. digital rectal examination

C. transrectal ultrasonography

D. human kallikrein 2

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4

What is the first-line chemotherapeutic agent for metastatic castration-resistant prostate cancer?

A. bisphosphonate

B. docetaxel

C. sipuleucel-T

D. enzalutamide