imperfect prostate biopsies
immature teratoma
schistosomiasis
liposarcoma
C. schistosomiasis
imperfect prostate biopsies
immature teratoma
schistosomiasis
liposarcoma
urethral stricture, impotence, and rectal bleeding
impotence, rectal bleeding, and urethral stricture
impotence, urethral stricture, and rectal bleeding
rectal bleeding, impotence, and urethral stricture
benign glands are different from malignant glands, as they contain basal cells
adenosis in the transitional zone carries 15% increase in cancer risk
the prostate has no discrete histologic capsule
intraductal carcinoma is morphologically worse than high-grade PIN and is typically associated with high-grade carcinoma
cryotherapy
chemotherapy
brachytherapy
radical prostatectomy
lymph nodes, bone, lung, bladder, liver, and adrenal glands
bone, lung, lymph nodes, liver, bladder, and adrenal glands
lung, liver, lymph nodes, bone, adrenal glands, and bladder
liver, lung, bone, lymph nodes, bladder, and adrenal glands
the number of freezing cycles
the lowest temperature achieved
the existence of regional heat sinks
all of the above
low risk
intermediate risk
high risk
data not adequate
a 12-core biopsy is the standard
in preparation for the procedure, a self-administered enema is suggested
sepsis might complicate the procedure
the biopsy path is best visualized in the coronal plane
survival rate
pathologic stage
extracapsular extension
lymph node involvement
4, 2 respectively
8, 5 respectively
6, 3 respectively
7, 4 respectively
commonly used in combination with a GnRH agonist
less effective than medical or surgical castration
not recommended for localized prostate cancer
inhibits various cytochrome P-450 enzymes
at average risk, aging 50 yrs., and have at least a 10-year life expectancy
aging 40 yrs., and had a first-degree relative diagnosed with prostate cancer before age 65
aging 40 yrs., African Americans
all of the above
patients who have a life expectancy ≤ 10 yrs. and/or well to moderately differentiated cancer
≥ 70 yrs. of age
PSA < 10 ng/mL, ratio < 0.22
patients with good performance status
GnRH agonists
antiandrogens
antimicrotubular
bisphosphonates
variants in the 8q24 region on chromosome 8, in sporadic cases
alterations on chromosome 1, chromosome 17, and the X chromosome, in some familial cases
the human prostate cancer gene is on the X chromosome
all are true
black individuals produce more PSA than whites
ejaculation can lead to a false decrease in PSA
pro-PSA is the serum proactive form of PSA molecule
prostate cancer cells make more PSA than normal prostate tissues do
hematospermia might persist for 4 6 weeks after taking biopsies
quinolone antibiotics prophylaxis eliminate possible infections
the right lateral decubitus position is commonly preferred
only hypoechoic lesions should be biopsied
ranges from 0 -10 based on a histologic evaluation of tumor specimens
based on the 2 most common histologic patterns
greatly relies on the skills and experience of the pathologist
a score of 7 indicates a moderate-grade or moderately differentiated tumor
the age of the patient
preoperative potency status
extent of nerve-sparing surgery
all of the above
elevated LH, elevated testosterone, elevated estrogen
elevated LH, elevated testosterone, declined estrogen
declined LH, declined testosterone, elevated estrogen
declined LH, elevated testosterone, declined estrogen
thyroid gland
breast tissue
adrenal glands
renal carcinomas
disruption of protein synthesis
coagulative necrosis
cell wall destruction
DNA damage
temporary incontinence
vasculogenic impotence
urinary retention
hyper-reflexive detrusor
prostate cancer
corpora amylacea
transitional zone
tuberculous prostatitis
reduces positive surgical margins
reduces local recurrence
has no proven advantage
reduces cardiac complications
pathologic tumor stage
performing nerve-sparing surgery
patient`s age
performing internal sphincter micro-dissection
85% of prostate adenocarcinomas are located in the peripheral zone
15% of them are multifocal
they tend to extend outside the prostate through the perineural space
the presence of perineural invasion does not worsen the prognosis
loss of one or both copies of the tumor suppressor gene PTEN
TMPRSS2ERG chromosome fusion
P53 mutations and overexpression of MYC
all of the above
PSA
digital rectal examination
transrectal ultrasonography
human kallikrein 2
bisphosphonate
docetaxel
sipuleucel-T
enzalutamide