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Current Affairs January 2024

What is the correct answer?

4

What is true surrounding PSA?

A. black individuals produce more PSA than whites

B. ejaculation can lead to a false decrease in PSA

C. pro-PSA is the serum proactive form of PSA molecule

D. prostate cancer cells make more PSA than normal prostate tissues do

Correct Answer :

A. black individuals produce more PSA than whites


self-explanatory.

Related Questions

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4

Solid lesions in the seminal vesicles are most likely to be a result of:

A. imperfect prostate biopsies

B. immature teratoma

C. schistosomiasis

D. liposarcoma

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4

Clinically significant prostate cancer is defined as:

A. volume ≥ 0.5 mL and/or a Gleason score of ≥ 3 + 4

B. volume ≥ 0.8 mL and/or a Gleason score of ≥ 4 + 4

C. volume ≥ 1.5 mL and/or a Gleason score of ≥ 4 + 3

D. volume ≥ 1.0 mL and/or a Gleason score of ≥ 3 + 3

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4

Fill the blanks: on treating prostate cancer patients, the median time from PSA failure to the development of metastatic disease after radical prostatectomy is approximately (…) yrs. and from the time of metastases to death is approximately (…) yrs..

A. 4, 2 respectively

B. 8, 5 respectively

C. 6, 3 respectively

D. 7, 4 respectively

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4

In which of the following situations prostate biopsy is most indicated?

A. normal DRE, abnormal PSA

B. abnormal DRE, abnormal PSA

C. abnormal DRE, normal PSA

D. hyperechoic areas on TRUS

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4

Regarding treating prostate cancer patients, watchful waiting is a reasonable option for:

A. patients who have a life expectancy ≤ 10 yrs. and/or well to moderately differentiated cancer

B. ≥ 70 yrs. of age

C. PSA < 10 ng/mL, ratio < 0.22

D. patients with good performance status

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4

What is the likelihood that patients with positive surgical margins after radical prostatectomy will be cured for prostate cancer?

A. never

B. unlikely

C. likely

D. always

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4

Concerning prostate cancers, a pre-treatment PSA velocity of > 2 ng/mL/yr is associated with an increased risk of:

A. pathological bone fractures

B. biochemical failure following radiation therapy

C. hepato-renal disease following chemotherapy

D. upgrading the pre-treatment risk stratification

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4

Regarding treating prostate cancer patients, watchful waiting strategy involves:

A. periodic PSA testing

B. periodic TRUS

C. all of the above

D. none of the above

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4

Regarding radical prostatectomy, the commonest site of positive surgical margins is the:

A. apex

B. posterior

C. postero-lateral

D. anterior

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4

What is false concerning prostate cancer?

A. the most common cause of mortality in men with prostate cancer is cardiac disease

B. is the second most common cause of cancer death in males

C. androgens have a pivotal role in prostate cancer development

D. low protein and high carbohydrate diet play a role in the development of prostate cancer

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4

Screening for prostate cancer is recommended for men who are:

A. at average risk, aging 50 yrs., and have at least a 10-year life expectancy

B. aging 40 yrs., and had a first-degree relative diagnosed with prostate cancer before age 65

C. aging 40 yrs., African Americans

D. all of the above

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4

What is false concerning TRUS prostatic biopsy?

A. a 12-core biopsy is the standard

B. in preparation for the procedure, a self-administered enema is suggested

C. sepsis might complicate the procedure

D. the biopsy path is best visualized in the coronal plane

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4

Which factor is closely related to the return to urinary continence function after radical retropubic prostatectomy?

A. pathologic tumor stage

B. performing nerve-sparing surgery

C. patient`s age

D. performing internal sphincter micro-dissection

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4

What is false regarding the diagnosis of prostate cancer?

A. most cases are identified by screening asymptomatic men

B. physical examination alone cannot reliably differentiate benign prostatic conditions from cancer

C. most diagnosed cases have normal DRE and PSA values

D. prostate biopsy establishes the diagnosis

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4

Which PSA value interpretation is incorrect?

A. > 50% of men with PSA > 10 ng/mL have the disease beyond the prostate

B. pelvic lymph node involvement is found in PSA > 20 ng/mL

C. 70% of men with a PSA between 4 and 10 ng/mL have organ-confined disease

D. 80% of men with PSA < 4 ng/mL have organ-confined disease

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4

What is true concerning TRUS prostatic biopsy?

A. hematospermia might persist for 4 6 weeks after taking biopsies

B. quinolone antibiotics prophylaxis eliminate possible infections

C. the right lateral decubitus position is commonly preferred

D. only hypoechoic lesions should be biopsied

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4

What if false concerning the prostate cancer marker PCA3?

A. entails a genetic analysis of cells in the voided urine

B. urine sample is collected after a firm massage of the prostate

C. helps screen patients who are at intermediate risk of cancer

D. helps avoid the inconvenience of prostate biopsy

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4

Following bilateral orchiectomy for prostate cancer, testosterone will:

A. initially drop to nadir, and then recover over 2 weeks

B. decline by 50% within 2 weeks and then normalize

C. decline by 90% within 24 hours

D. decline by 70%

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4

What fraction of men with a PSA value between 4 and 10 ng/mL has an organ-confined prostate cancer?

A.

B. ¼

C. ½

D.

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4

Prostate-specific membrane antigen has been detected in:

A. the prostate gland only

B. the central nervous system, intestine, and the prostate

C. malignant ovarian cysts, skeletal muscles, and the prostate

D. thyroid glands, adrenals, and the prostate

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4

Partin tables are probability tables for the determination of pathologic stages of prostatic cancers based on:

A. preoperative clinical stage, PSA level, and Gleason sum

B. seminal vesicle invasion, lymph node metastases, and Gleason sum

C. positive surgical margins, capsular penetration, and PSA level

D. PSA level, perineural invasion, vascular metastasis, and Gleason sum

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4

What is true regarding seminal vesicles` involvement in prostate cancer?

A. is almost always due to direct extension (T2c)

B. it is involved in 85% of positive surgical margins following radical prostatectomy

C. it carries a poor prognosis

D. none of the above

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4

Ectopic expression of PSA occurs in all of the following, EXCEPT:

A. thyroid gland

B. breast tissue

C. adrenal glands

D. renal carcinomas

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4

All of the following modalities are used as salvage therapies after failing radiation therapy for prostate cancer treatment, EXCEPT:

A. cryotherapy

B. chemotherapy

C. brachytherapy

D. radical prostatectomy

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4

In descending order, to where do prostate cancers metastasize?

A. lymph nodes, bone, lung, bladder, liver, and adrenal glands

B. bone, lung, lymph nodes, liver, bladder, and adrenal glands

C. lung, liver, lymph nodes, bone, adrenal glands, and bladder

D. liver, lung, bone, lymph nodes, bladder, and adrenal glands

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4

What condition does NOT appear as a hypoechoic lesion in the prostate on TRUS?

A. prostate cancer

B. corpora amylacea

C. transitional zone

D. tuberculous prostatitis

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4

What is false concerning thawing procedure to treat prostate cancer cells?

A. slow thawing is more effective than rapid thawing

B. the most common complication is erectile dysfunction

C. for effective thawing a minimum temperature of − 25° C and a double freeze/thaw cycle with urethral warming are recommended

D. the two most common modalities employed in focal therapy are highintensity focused ultrasound and cryosurgery

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4

What is false concerning Gleason scoring system for prostate cancers?

A. ranges from 0 -10 based on a histologic evaluation of tumor specimens

B. based on the 2 most common histologic patterns

C. greatly relies on the skills and experience of the pathologist

D. a score of 7 indicates a moderate-grade or moderately differentiated tumor

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4

Regarding radiotherapy for prostate cancer, what is the lowest recommended dose for salvage therapy?

A. 54 Gy

B. 64 Gy

C. 74 Gy

D. 84 Gy

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4

What are the possible complications of CO2 pneumoperitoneum during laparoscopic/robotic prostatectomy?

A. hypoxia and acidosis

B. tachycardia and tachypnea

C. bradycardia and hypotension

D. hypercarbia and oliguria