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Current Affairs January 2024

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4

What condition does NOT appear as a hypoechoic lesion in the prostate on TRUS?

A. prostate cancer

B. corpora amylacea

C. transitional zone

D. tuberculous prostatitis

Correct Answer :

B. corpora amylacea


corpora amylacea are calcifications within the prostate gland that appear densely hyperechoic.

Related Questions

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4

What is false concerning thawing procedure to treat prostate cancer cells?

A. slow thawing is more effective than rapid thawing

B. the most common complication is erectile dysfunction

C. for effective thawing a minimum temperature of − 25° C and a double freeze/thaw cycle with urethral warming are recommended

D. the two most common modalities employed in focal therapy are highintensity focused ultrasound and cryosurgery

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4

Genetically, increased risk of prostate cancer has been found in men with:

A. variants in the 8q24 region on chromosome 8, in sporadic cases

B. alterations on chromosome 1, chromosome 17, and the X chromosome, in some familial cases

C. the human prostate cancer gene is on the X chromosome

D. all are true

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4

What condition does NOT appear as a hypoechoic lesion in the prostate on TRUS?

A. prostate cancer

B. corpora amylacea

C. transitional zone

D. tuberculous prostatitis

What is the correct answer?

4

What is false concerning the interpretation of Gleason scoring system?

A. a low score means the cancer tissue is similar to normal prostate tissue

B. it indicates how likely the tumor will spread

C. the more cellular atypia observed the higher scoring will be

D. it relies only on the glandular architectural pattern

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4

In which of the following cases PSA testing is NOT indicated:

A. 72 yrs. man newly diagnosed BPH with normal DRE

B. 2 weeks post TURP for obstructing cancerous prostate

C. screening for prostate cancer in 75 yrs. old Caucasian man

D. 43 yrs. man with obstructive LUTS, who had a first-degree relative diagnosed with prostate cancer before age 65

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4

What is the proper pre-treatment risk stratification of prostate cancer for a patient with T2a, PSA < 11 ng/mL, and no Gleason score > 6?

A. low risk

B. intermediate risk

C. high risk

D. data not adequate

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4

What is false regarding the diagnosis of prostate cancer?

A. most cases are identified by screening asymptomatic men

B. physical examination alone cannot reliably differentiate benign prostatic conditions from cancer

C. most diagnosed cases have normal DRE and PSA values

D. prostate biopsy establishes the diagnosis

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4

Regarding radical prostatectomy, the commonest site of positive surgical margins is the:

A. apex

B. posterior

C. postero-lateral

D. anterior

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4

What pathologic findings after radical prostatectomy are predictive for occult metastases?

A. seminal vesicle invasion and lymph node metastases

B. positive surgical margins and seminal vesicle involvement

C. capsular penetration and lymph node metastases

D. rectal and bladder neck involvement

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4

What fraction of men with a PSA value between 4 and 10 ng/mL has an organ-confined prostate cancer?

A.

B. ¼

C. ½

D.

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4

What is false concerning prostate cancer?

A. the most common cause of mortality in men with prostate cancer is cardiac disease

B. is the second most common cause of cancer death in males

C. androgens have a pivotal role in prostate cancer development

D. low protein and high carbohydrate diet play a role in the development of prostate cancer

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4

Screening for prostate cancer is recommended for men who are:

A. at average risk, aging 50 yrs., and have at least a 10-year life expectancy

B. aging 40 yrs., and had a first-degree relative diagnosed with prostate cancer before age 65

C. aging 40 yrs., African Americans

D. all of the above

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4

Which of the following tests has the highest positive predictive value for prostate cancer?

A. PSA

B. digital rectal examination

C. transrectal ultrasonography

D. human kallikrein 2

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4

What are the possible complications of CO2 pneumoperitoneum during laparoscopic/robotic prostatectomy?

A. hypoxia and acidosis

B. tachycardia and tachypnea

C. bradycardia and hypotension

D. hypercarbia and oliguria

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4

For prostate cancer patients, what do Partin tables predict?

A. survival rate

B. pathologic stage

C. extracapsular extension

D. lymph node involvement

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4

What is false regarding the histology of prostatic cancers?

A. benign glands are different from malignant glands, as they contain basal cells

B. adenosis in the transitional zone carries 15% increase in cancer risk

C. the prostate has no discrete histologic capsule

D. intraductal carcinoma is morphologically worse than high-grade PIN and is typically associated with high-grade carcinoma

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4

What is true regarding seminal vesicles` involvement in prostate cancer?

A. is almost always due to direct extension (T2c)

B. it is involved in 85% of positive surgical margins following radical prostatectomy

C. it carries a poor prognosis

D. none of the above

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4

Following bilateral orchiectomy for prostate cancer, testosterone will:

A. initially drop to nadir, and then recover over 2 weeks

B. decline by 50% within 2 weeks and then normalize

C. decline by 90% within 24 hours

D. decline by 70%

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4

What is the likelihood that patients with positive surgical margins after radical prostatectomy will be cured for prostate cancer?

A. never

B. unlikely

C. likely

D. always

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4

Regarding radiotherapy for prostate cancer, what is the lowest recommended dose for salvage therapy?

A. 54 Gy

B. 64 Gy

C. 74 Gy

D. 84 Gy

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4

What is true surrounding PSA?

A. black individuals produce more PSA than whites

B. ejaculation can lead to a false decrease in PSA

C. pro-PSA is the serum proactive form of PSA molecule

D. prostate cancer cells make more PSA than normal prostate tissues do

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4

What class of prostate cancer medications causes an initial increase in LH, FSH levels and consequently a rise in testosterone level for few weeks?

A. GnRH agonists

B. antiandrogens

C. antimicrotubular

D. bisphosphonates

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4

What are the clinical parameters of tissue ablation achieved by cryotherapy for cancer cells destruction?

A. the number of freezing cycles

B. the lowest temperature achieved

C. the existence of regional heat sinks

D. all of the above

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4

Solid lesions in the seminal vesicles are most likely to be a result of:

A. imperfect prostate biopsies

B. immature teratoma

C. schistosomiasis

D. liposarcoma

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4

BPH patients on finasteride longer than 6 months are expected to have:

A. decreased t-PSA but increased f-PSA

B. decreased t-PSA but unaltered f-PSA

C. decreased t-PSA and decreased f-PSA

D. any of the above

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4

What advantage does laparoscopic/robotic prostatectomy has over open surgery in treating prostate cancers?

A. preserving potency

B. avoiding incontinence

C. less bleeding

D. all of the above

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4

What is the likelihood that prostate cells die in a single freeze cycle of cryotherapy when tissue temperature reaches colder than - 400 C?

A. never

B. unlikely

C. likely

D. always

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4

What is false concerning antiandrogen class of prostate cancer medications?

A. commonly used in combination with a GnRH agonist

B. less effective than medical or surgical castration

C. not recommended for localized prostate cancer

D. inhibits various cytochrome P-450 enzymes

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4

In which of the following PSA readings prostate cancer is least suspected?

A. PSA velocity of 0.35 ng/mL/y, when the PSA is ≤ 2.5 ng/mL

B. PSA velocity of 0.75 ng/mL/y, when the PSA is 4 10 ng/mL

C. t-PSA is 2.8 ng/mL, f-PSA 0.94 ng/mL

D. t-PSA is 3.7 ng/mL, f-PSA 0.51 ng/mL

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4

In descending order, the commonest complications of external beam radiation therapy for prostate cancer are:

A. urethral stricture, impotence, and rectal bleeding

B. impotence, rectal bleeding, and urethral stricture

C. impotence, urethral stricture, and rectal bleeding

D. rectal bleeding, impotence, and urethral stricture