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What is the correct answer?

4

What medication could help in managing carbonate apatite stones?

A. α-Mercaptopropionylglycine

B. acetohydroxamic acid

C. carbonic anhydrase inhibitors

D. xanthine oxidase inhibitors

Correct Answer :

B. acetohydroxamic acid


Acetohydroxamic acid (AHA) is a competitive inhibitor of the bacterial enzyme urease that reduces the urinary saturation of carbonate apatite stones.

Related Questions

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4

What is the most favorable stone characteristics for laparoscopic and robotic approaches for the treatment of a kidney stone?

A. a stone in the lower calyx with a wide mouth of infundibulum and obtuse lower calyx to ureter angle

B. a stone in an anterior group calyceal diverticulum with thin overlying renal parenchyma

C. 5 mm calcium-containing stone in an intrarenal pelvis and wide UPJ

D. 6 years post anatrophic nephrolithotomy, recurrent mid calyceal stone

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4

In what kind of renal stones do antibiotics help most?

A. indinavir

B. magnesium ammonium phosphate

C. xanthine

D. matrix

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4

What is (are) the indication(s) of hospitalization of ureteral stone patients?

A. steinstrasse

B. a stone in ureterocele

C. fever, leucocytosis, pain

D. brushite stones

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4

What is (are) the indication(s) of using DJ ureteral catheters?

A. to stent the ureter after ureteral surgery

B. to facilitate stone passage

C. after a tough ureteroscopy procedure

D. all of the above

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4

What is the most favorable stone characteristic for PCNL treatment?

A. ≥ 2 cm diameter

B. upper calyx location

C. Na.urate composition

D. 600 - 800 HU density

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4

What does nephrocalcin do?

A. dissolves cystine stones

B. enhances nephrocalcinosis process over old scared areas

C. inhibits Ca.oxalate aggregation and crystallization

D. plays a secondary role in metastatic calcification process

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4

What is true regarding DJ ureteral stents?

A. can be placed through perc. nephrostomy

B. might slip out, especially in females

C. usually radiopaque

D. all of the above

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4

What is false concerning the use of antibiotics in stone patients?

A. they are mandatory when urine shows ≥ 10 WBCs/hpf in symptomatic patients

B. they aim at treating pyonephrosis and urosepsis

C. they should cover Escherichia coli and Staphylococcus, Enterobacter, Proteus, and Klebsiella species

D. All of the above

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4

What kind of stones is most amenable to ESWL?

A. cystine

B. brushite

C. Ca.oxalate monohydrate

D. Ca.oxalate dihydrate

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4

What is true regarding a stone in a urethral diverticulum?

A. is symptomless

B. should undergo a trial of milking out

C. diverticulectomy and stone extraction is the treatment of choice

D. ESWL is the preferred treatment option

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4

What are the expected findings on urinalysis in patients with acute renal colic?

A. blood cells more than pus cells

B. pus cells if infection was superadded

C. crystals might appear

D. all of the above

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4

What is true concerning primary hyperparathyroidism and stone formation?

A. orthophosphates may have a role in the treatment

B. hyperparathyroidectomy and levothyroxine replacement is the optimum treatment

C. management includes Calcium chelating agent and repeat 24hr urine collection in 3 months

D. surgical excision of the adenoma(s) is the treatment of choice

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4

Which patient is at lowest risk for the development of perinephric hematoma after ESWL?

A. hypertensive patient

B. patient on aspirin withheld 5 days prior to ESWL

C. a stone in a scared poorly functioning kidney

D. ESWL every other day

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4

What medication could help in managing carbonate apatite stones?

A. α-Mercaptopropionylglycine

B. acetohydroxamic acid

C. carbonic anhydrase inhibitors

D. xanthine oxidase inhibitors

What is the correct answer?

4

What statement is false concerning the use of desmopressin (DDAVP) in renal colic patients?

A. it causes reduction in the mean intra-ureteral pressure

B. it reduces the pain of acute renal colic

C. it has a direct relaxing effect on the renal pelvis and ureteral musculature

D. it is indicated when stones are ≤ 4 mm in diameter

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4

What is the most common organism that might complicate PCNL?

A. Proteus mirabilis

B. E. coli

C. Pseudomonas aeruginosa

D. Staphylococcus epidermidis

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4

What stone is inherited as an autosomal recessive trait?

A. xanthine

B. ammonium urate

C. cystine

D. calcium oxalate dihydrate

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4

Which statement is false concerning renal stones related to hyperparathyroidism (HPT)?

A. renal stones are found in 20% of patients with primary HPT

B. acidic arrest promotes crystallisation of calcium phosphate stones related to HPT

C. HPT, vitamin D excess, and malignancy could lead to hypercalcemia and hypercalciuria

D. only surgery can cure primary HPT

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4

When should renal stone patients be evaluated for metabolic diseases?

A. when stones are multiple and/or recurrent

B. when stones form in childhood

C. in cases where nephrocalcinosis and urolithiasis are present

D. all of the above

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4

As per the fixed particle theory of stone formation:

A. the initial step is papillary plaque formation

B. crystals formation occurs inside the nephron

C. tubular precipitates form harmless crystalluria

D. the attraction of organic compounds and activation crystallization is regulated by osteopontin

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4

What is the principal defect in renal hypercalciuria?

A. impaired renal tubular calcium reabsorption

B. excessive glomerular leak of calcium

C. deficiency of the enzyme xanthine oxidase

D. hypercalcemia

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4

What is false regarding hypomagnesuric calcium nephrolithiasis?

A. it is characterized by low urinary magnesium and citrate

B. magnesium increases renal tubular citrate resorption

C. diarrheal is a remarkable side effect of magnesium therapy

D. potassium-magnesium preparations might restore urinary magnesium and citrate levels

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4

How is primary oxaluria treated?

A. terminal ilium resection

B. liver transplantation

C. kidney transplantation

D. regular hemodialysis

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4

What is the incidence risk of ureteral strictures following ureteroscopy?

A. 3 6 %

B. 12 15 %

C. 0.4 0.8 %

D. 0.09 0.14 %

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4

What is false concerning cystine stones?

A. result from an inherited defect of renal tubular reabsorption of cysteine

B. characteristically, urate and cysteine stone are radiolucent

C. cysteine is a dibasic amino acid

D. on plain X-ray, cysteine stones exhibit ground-glass appearance

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4

What is the unfavorable stone characteristic for a rigid URS treatment?

A. size of 5 mm

B. location at the lower calyx

C. density of 400 HU

D. being recurrent

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4

What is false concerning urethral stones?

A. stones at posterior urethra could be pushed back to the bladder

B. stones at anterior urethra have to undergo a trial of milking out, using copious intra-urethral xylocaine gel

C. often respond to a two-week course of tamsulosin

D. respond to Holmium laser treatment

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4

How does oral Mg.citrate inhibit Ca.oxalate stone formation?

A. by lowering urinary saturation of Ca.oxalate

B. by preventing heterogeneous nucleation of Ca.oxalate

C. by inhibiting spontaneous precipitation and agglomeration of Ca.oxalate

D. by all of the above

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4

What is the Hounsfield density range of uric acid stones?

A. 400 600 HU

B. 600 800 HU

C. 800 1000 HU

D. 1000 1200 HU

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4

A 24-hr urine collection of a recurrent Ca. oxalate stone former patient having Crohn`s disease might reveal:

A. high citrate, high oxalate

B. low citrate, low oxalate

C. high citrate, low oxalate

D. low citrate, high oxalate