Which of the following conditions carries the worst prognosis?
acquired cystic renal disease
juvenile nephronophthisis
medullary sponge kidney
bilateral multicystic dysplastic kidney
Correct Answer :
D. bilateral multicystic dysplastic kidney
bilateral MCDK is incompatible with life.
Related Questions
d. 19 - 26%
. What is false regarding radical nephrectomy operation?
nodal involvement doesn`t influence prognosis
renal artery should be ligated before the vein to avoid kidney ballooning
cardiopulmonary bypass with deep hypothermic circulatory arrest is performed in patients with supra-diaphragmatic tumor thrombi
d. prior to kidney transplant
. What is an indication for radical nephrectomy?
a 6-cm, polar tumor
bilateral RCC
locally advanced RCC
What is false concerning renal oncocytoma?
the central scar on CT or MRI, and the spoke-wheel pattern of vessels on angiograms are not specific to oncocytoma
calcification, necrosis, and hemorrhage are rare in oncocytomas
it is thought to arise from the basement membrane of proximal convoluted tubules
treatment is partial nephrectomy or tumor excision
According to Fuhrmans classification system for nuclear grading in RCC, nuclear size of 20 μg with irregular outline and prominent nucleoli is grade:
1
2
3
4
What is true regarding cancer incidence in renal cystic diseases?
is > 90% in Bosniak type IV renal cysts
in patients receiving renal transplants for polycystic kidney disease is 48% higher than that expected in the general population
all of the above
simple renal cysts might turn malignant in < 4% of cases
What is the most common cause of genetic ESRD in children?
autosomal recessive polycystic kidney disease
autosomal dominant polycystic kidney disease
multicystic dysplastic kidney disease
juvenile nephronophthisis
Which of the following renal tumors carries the best prognosis?
fibrosarcoma
leiomyosarcoma
carcinoid
adult Wilm`s tumor
On histological examination of a resected renal tumor, the presence of multiple mitochondria observed on electron microscopy is diagnostic for:
renal oncocytoma
multiloculated cystic nephromas
metanephric adenoma
adenoma with clear cell
The etiology of renal cysts includes all of the following, EXCEPT:
autosomal dominant polycystic kidney disease (ADPKD)
developmental cystic renal disease
inherited cystic renal disease
systemic disease with associated renal cysts
In RCC cases where IVC involvement with tumor thrombi are suspected, venacavography:
is the first and most reliable radiologic examination to study IVC thrombi
is reserved for patients with equivocal MRI or CT findings
is obsolete and has fallen out of use
carries a risk of IVC terrible bleeding that outweighs the diagnostic merits
On histological examination of a resected renal tumor, positive staining for human melanoma black (HMB)-45 is a distinctive and diagnostic feature for:
multiloculated cystic nephromas
angiomyolipoma
metanephric adenoma
adenoma with clear cell
What is the proper terminology of a renal cyst with the following characteristics: well-marginated, anechoic, with thin visible back wall, positive posterior acoustic enhancement, no septations, and no calcifications?
hyperattenuating renal cyst
solitary renal cyst
uncomplicated renal cyst
focal renal cyst
What is the treatment of a 3-cm renal mass suggestive of RCC adjacent to a huge renal cyst?
cyst aspiration and sclerosis
partial nephrectomy
endoscopic marsupialization and fulguration of the cyst
administration of TKIs
Regarding simple renal cysts, fluid attenuation on non-contrast CT series is:
< - 10 HU
< - 20 HU
< 10 HU
< 20 HU
What is false concerning renal cancers?
papillary subtype of RCC has a tendency to multifocality
chromosome 13 alterations are common in the development of clear cell renal carcinoma
a solid mass on CT that enhances more than 15 HU is suggestive of RCC
bilateral involvement in RCC either synchronously or metachronously occurs in 2% to 4% of patients
The likelihood of malignancy in category IIF (indeterminate) renal cysts is:
20%
30%
40%
50%
After radical nephrectomy, what is the 5-year survival rate for stage I RCC?
80%
85%
90%
95%
d. neurosarcoma
. What is false concerning targeted molecular therapy?
is a personalized medical therapy devised to meet each persons individual needs for cancer`s specifications
treats cancer by interrupting unique molecular abnormalities that drive cancer growth
some cancer types have different molecular targets
The diagnosis of renal adenoma is commonly made:
at autopsy
by staining positive for human melanoma black (HMB)-45
by fine-needle aspiration cytology
by exclusion
d. renal vein thrombi can be resected after incising the vein between 2 vascular clamps
. Manifestations of paraneoplastic syndrome associated with RCC include all of the following, EXCEPT:
anemia and erythrocytosis
hepatic dysfunction and elevated human chorionic gonadotropin levels
hypocalcemia
Antenatal sonography is the diagnostic tool for the following condition:
glomerulocystic kidney disease
developmental cystic renal disease
Juvenile nephronophthisis
medullary cystic kidney disease
Which of the following factors is associated with increased survival in patients with metastatic kidney tumors?
physically active patients with good performance status
extirpation of the primary tumor
long disease-free interval between initial nephrectomy and the emergence of secondaries
all of the above
What is false concerning metanephric adenoma?
radiographically, it is indistinguishable from RCC
has a female predominance
has a benign clinical course
has a peak incidence in the third decade of life
Which of the following conditions carries the best prognosis?
acquired cystic renal disease
juvenile nephronophthisis
medullary sponge kidney
bilateral multicystic dysplastic kidney
Fuhrmans grading system for renal cell carcinoma relies on:
nuclear size, outline, and nucleoli
cohesiveness and the degree of cellular atypia
chromatin structure and content of the interphase nucleus
multinucleation and mitosis
Which of the following conditions carries the worst prognosis?
acquired cystic renal disease
juvenile nephronophthisis
medullary sponge kidney
bilateral multicystic dysplastic kidney
d. hypertension
. Metastatic tumors to the kidney are common from all of the following organs, EXCEPT:
lungs
thyroid
breasts
What is (are) the risk factor(s) for developing simple renal cysts?
male gender
hypertension
renal insufficiency
all of the above
Which of the following is NOT a risk factor for RCC?
type II DM, especially in males
hypertension
obesity, especially in females
cigarette smoking
d. melanoma
. The second most common RCC subtype is:
collecting duct b. clear cell
papillary
chromophobe