Which class of the following agents does NOT impair spermatogenesis?
alkylating agents
phenothiazines
antiandrogens
prostaglandins
Correct Answer :
B. phenothiazines
chemotherapeutics such as alkylating agents impair spermatogenesis, as do so drugs affecting endocrine functions e.g. prostaglandins, and antiandrogens.
Related Questions
The majority of circulating testosterone is:
bound to sex hormone-binding globulin
free
bound to α1-antichymotrypsin
bound to albumin
Which statement is false concerning the epididymis?
each epididymis can be palpable at the postero-lateral surface of the testis
has 3 parts; head, body, and tail
new batches of sperms stay in the epididymis around 2 days for maturation
shares the same blood supply of the testis
Where is the gene sex-determining region (SRY) located at?
long arm of X chromosome
long arm of Y chromosome
short arm of Y chromosome
short arm of X chromosome
What is the appropriate intravenous maintenance fluid for a 16 kg girl?
43 ml/hr of normal saline
78 ml/hr of ¼ normal saline
69 ml/hr of ½ normal saline
54 ml/hr of ¼ normal saline
What vessels are located in the prostate neurovascular bundle?
Watson plexus
capsular arteries and veins
inferior vesical and midrectal vessels
Santorini plexus
At which type of renal tubular acidosis (RTA), typically, potassium levels increase?
type 1
type 2
type 3
type 4
Which microbe causes red diaper syndrome?
Serratia marcescens
Streptococcus pyogenes
Clostridium difficile
Staphylococcus saprophyticus
What is the nature of the prostate-specific antigen?
protease
lyase
carboxylase
hydrolase
Which of the following contributes second to the seminal fluid by volume?
seminal vesicles
the prostate
testes
bulbourethral glands
What is false concerning fosfomycin antibiotic?
has a limited cross-resistance with most common antibacterial agents
causes injection site reactions
is active against most uropathogens
is effective as a single-dose agent
Which statement is false concerning the dipstick method for detecting hematuria?
depends on the ability of hemoglobin to oxidize a chromogen indicator
negative results need to be confirmed by microscopic examination
has a sensitivity of 95% and a specificity of 75%
the presence of many epithelial cells suggests skin or vaginal contamination
Which part of the prostate is traversed by the ejaculatory duct:
central zone
peripheral zone
transitional zone
fibromuscular stroma
Which agent is most likely to cause hemorrhagic cystitis?
cisplatin
ifosfamide
phosphomycin
amphotericin B
What is the prime effect of antidiuretic hormone on kidneys?
increase collecting duct permeability
increase medullary blood flow
decrease cortical blood flow
decrease potassium secretion
The epithelial component of the prostate consists of all of the following, EXCEPT:
basal cells
intermediate cells
tubulo-columnar cells
neuroendocrine cells
Where is Santorini plexus located?
at either side of the prostate
in the pubo-prostatic space
anterior to the seminal vesicles
posterior to the vaso-epididymal junction
Regarding renal ectopia, usually, the adrenals:
are cross ectopic
are at their normal position
travel with the kidneys
undergo ischemic atrophy
Which antibiotic is the best to treat soft tissue infection with methicillin-resistant Staphylococcus aureus (MRSA) in hospitalized patients?
vancomycin
cefotaxime
penicillin G
tobramycin
What is false concerning the collecting system structures of a typical kidney?
the renal pelvis could be intra or extra renal
the renal pelvis divides into 2 or 3 major calyces
major calyces divide into 2 or 3 minor calyces
unlike lateral calyces, polar calyces are often paired
Which statement is true about the female urethra?
harder to catheterize when compared to the male urethra
4 inch long
opens into the vestibule below the clitoris
gets wider at the post-menopausal age
Hematuria of glomerular origin is associated with:
significant proteinuria, dysmorphic RBCs, RBC casts
glycosuria, eumorphic RBCs, WBC casts
hypercalciuria, eumorphic RBCs, granular casts
proteinuria, dysmorphic RBCs, hyaline casts
By which of the following structures, do the fused lower poles of hoarseshoe kidneys get trapped during embryologic ascent?
inferior mesenteric artery
superior mesenteric artery
celiac artery
common iliac artery
Which of the following is NOT a cause of hypocitraturia?
high protein diet
hypokalaemia
proximal renal tubular acidosis
idiopathic
Which lab results indicate poor prognosis of male infertility?
azoospermia; normal FSH; increase LH
azoospermia; decrease FSH; normal LH
oligospermia; increase FSH; normal LH
oligospermia; normal FSH; decrease LH
At what month of intra-uterine life do testes descend into the scrotum with the aid of the intra-abdominal pressure and the gubernacula?
sixth
seventh
eighth
ninth
Which of the following explains infertility in liver cirrhosis male patients?
decrease plasma estradiol levels
increase plasma testosterone-estradiol-binding globulin levels
suppression of suprarenal androgens
exaggerated pituitary response to feedback hormones
Which of the prostate medications could result in significant hypotension?
finasteride
prazosin
silodosin
vardenafil
What causes ureteral dilation during pregnancy is:
mechanical compression by the gravid uterus
physiological increase urine flow during pregnancy
elevated levels of progesterone
reflex inhibition of ureteral contractions
Which of the following process(es) is (are) reversible?
5α-reductase enzyme reduces testosterone to DHT
aromatase enzyme reduces testosterone to estrogen
PSA molecule binds to α1-antichymotrypsin and α2-macroglobulin
none of the above
On tracing the IVU dye down, in a dilated ureter, the dilation stops at a level then continues as a normal calibre ureter. What could the pathology be?
lower ureteral stricture
ureteral valve
modified Lich-Gregoire ureteral reimplantation
residual dilation of hydroureter